Performance of Plasma Coproporphyrin I and III as OATP1B1 Biomarkers in Humans

por Neuvonen, Mikko, Tornio, Aleksi, Hirvensalo, Päivi, Backman, Janne T., Niemi, Mikko
Publicado 2021

Pharmacogenomics of celiprolol – evidence for a role of P‐glycoprotein and organic anion transporting polypeptide 1A2 in celiprolol pharmacokinetics

por Hirvensalo, Päivi, Tornio, Aleksi, Tapaninen, Tuija, Paile‐Hyvärinen, Maria, Neuvonen, Mikko, Backman, Janne T., Niemi, Mikko
Publicado 2021

CYP2D6 intermediate metabolizer status could slow down Plasmodium falciparum gametocyte clearance after single-dose primaquine

por Pett, Helmi, Drakeley, Chris, Eziefula, Chi, Neuvonen, Mikko, Lanke, Kjerstin, Sauerwein, Robert, Niemi, Mikko, Bousema, Teun
Publicado 2014

Rifampin Reduces the Plasma Concentrations of Oral and Intravenous Hydromorphone in Healthy Volunteers

por Lohela, Terhi J., Poikola, Satu, Neuvonen, Mikko, Niemi, Mikko, Backman, Janne T., Olkkola, Klaus T., Lilius, Tuomas O.
Publicado 2020

Clopidogrel but Not Prasugrel Significantly Inhibits the CYP2C8‐Mediated Metabolism of Montelukast in Humans

por Itkonen, Matti K., Tornio, Aleksi, Filppula, Anne M., Neuvonen, Mikko, Neuvonen, Pertti J., Niemi, Mikko, Backman, Janne T.
Publicado 2017

Clopidogrel Increases Dasabuvir Exposure With or Without Ritonavir, and Ritonavir Inhibits the Bioactivation of Clopidogrel

por Itkonen, Matti K., Tornio, Aleksi, Lapatto‐Reiniluoto, Outi, Neuvonen, Mikko, Neuvonen, Pertti J., Niemi, Mikko, Backman, Janne T.
Publicado 2018

Itraconazole Increases Ibrutinib Exposure 10‐Fold and Reduces Interindividual Variation—A Potentially Beneficial Drug‐Drug Interaction

por Tapaninen, Tuija, Olkkola, Aleksi M., Tornio, Aleksi, Neuvonen, Mikko, Elonen, Erkki, Neuvonen, Pertti J., Niemi, Mikko, Backman, Janne T.
Publicado 2019

Enantiospecific Pharmacogenomics of Fluvastatin

por Hirvensalo, Päivi, Tornio, Aleksi, Neuvonen, Mikko, Kiander, Wilma, Kidron, Heidi, Paile‐Hyvärinen, Maria, Tapaninen, Tuija, Backman, Janne T., Niemi, Mikko
Publicado 2019

Comprehensive Pharmacogenomic Study Reveals an Important Role of UGT1A3 in Montelukast Pharmacokinetics

por Hirvensalo, Päivi, Tornio, Aleksi, Neuvonen, Mikko, Tapaninen, Tuija, Paile‐Hyvärinen, Maria, Kärjä, Vesa, Männistö, Ville T., Pihlajamäki, Jussi, Backman, Janne T., Niemi, Mikko
Publicado 2017

Febuxostat, But Not Allopurinol, Markedly Raises the Plasma Concentrations of the Breast Cancer Resistance Protein Substrate Rosuvastatin

por Lehtisalo, Minna, Keskitalo, Jenni E., Tornio, Aleksi, Lapatto‐Reiniluoto, Outi, Deng, Feng, Jaatinen, Taina, Viinamäki, Jenni, Neuvonen, Mikko, Backman, Janne T., Niemi, Mikko
Publicado 2020

Protein Phosphatase 1 Regulatory Subunit 3B Genotype at rs4240624 Has a Major Effect on Gallbladder Bile Composition

por Männistö, Ville, Kaminska, Dorota, Käkelä, Pirjo, Neuvonen, Mikko, Niemi, Mikko, Alvarez, Marcus, Pajukanta, Päivi, Romeo, Stefano, Nieuwdorp, Max, Groen, Albert.K., Pihlajamäki, Jussi
Publicado 2020

Circulating oxylipin and bile acid profiles of dexmedetomidine, propofol, sevoflurane, and S-ketamine: a randomised controlled trial using tandem mass spectrometry

por Nummela, Aleksi, Laaksonen, Lauri, Scheinin, Annalotta, Kaisti, Kaike, Vahlberg, Tero, Neuvonen, Mikko, Valli, Katja, Revonsuo, Antti, Perola, Markus, Niemi, Mikko, Scheinin, Harry, Laitio, Timo
Publicado 2022

Genomewide Association Study of Simvastatin Pharmacokinetics

por Mykkänen, Anssi J. H., Taskinen, Suvi, Neuvonen, Mikko, Paile‐Hyvärinen, Maria, Tarkiainen, E. Katriina, Lilius, Tuomas, Tapaninen, Tuija, Backman, Janne T., Tornio, Aleksi, Niemi, Mikko
Publicado 2022

A comprehensive pharmacogenomic study indicates roles for SLCO1B1, ABCG2 and SLCO2B1 in rosuvastatin pharmacokinetics

por Lehtisalo, Minna, Taskinen, Suvi, Tarkiainen, E. Katriina, Neuvonen, Mikko, Viinamäki, Jenni, Paile‐Hyvärinen, Maria, Lilius, Tuomas O., Tapaninen, Tuija, Backman, Janne T., Tornio, Aleksi, Niemi, Mikko
Publicado 2022

Extraesophageal reflux and reflux aspiration in dogs with respiratory diseases and in healthy dogs

por Kouki, Sirkku, Viitanen, Sanna J., Koho, Ninna, Laurila, Henna P., Lilja‐Maula, Liisa, Holopainen, Saila, Neuvonen, Mikko, Niemi, Mikko, Fastrès, Aline, Clercx, Cécile, Rajamäki, Minna M.
Publicado 2023

The effect of hydroxychloroquine on cholesterol metabolism in statin treated patients after myocardial infarction

por Ulander, Lotta, Simonen, Piia, Tolppanen, Heli, Hartman, Otto, Rissanen, Tuomas T., Eklund, Kari K., Kalaoja, Marita, Kurkela, Mika, Neuvonen, Mikko, Niemi, Mikko, Backman, Janne T., Gylling, Helena, Sinisalo, Juha
Publicado 2023

Identification of Glycochenodeoxycholate 3‐O‐Glucuronide and Glycodeoxycholate 3‐O‐Glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers

por Neuvonen, Mikko, Hirvensalo, Päivi, Tornio, Aleksi, Rago, Brian, West, Mark, Lazzaro, Sarah, Mathialagan, Sumathy, Varma, Manthena, Cerny, Matthew A., Costales, Chester, Ramanathan, Ragu, Rodrigues, A. David, Niemi, Mikko
Publicado 2020

Reflux aspiration in lungs of dogs with respiratory disease and in healthy West Highland White Terriers

por Määttä, O. L. Merita, Laurila, Henna P., Holopainen, Saila, Lilja‐Maula, Liisa, Melamies, Marika, Viitanen, Sanna J., Johnson, L. R., Koho, Ninna, Neuvonen, Mikko, Niemi, Mikko, Rajamäki, Minna M.
Publicado 2018

CYP2D6 Polymorphisms and the Safety and Gametocytocidal Activity of Single-Dose Primaquine for Plasmodium falciparum

por Pett, Helmi, Bradley, John, Okebe, Joseph, Dicko, Alassane, Tiono, Alfred B., Gonçalves, Bronner P., Stone, Will, Chen, Ingrid, Lanke, Kjerstin, Neuvonen, Mikko, Mustaniemi, Anna-Liina, Eziefula, Alice C., Gosling, Roly, D’Alessandro, Umberto, Drakeley, Chris, Niemi, Mikko, Bousema, Teun
Publicado 2019