Determining the Molecular Pathways Underlying the Protective Effect of Non-Steroidal Anti-Inflammatory Drugs for Alzheimer's Disease: A Bioinformatics Approach

por Nevado-Holgado, Alejo J, Lovestone, Simon
Publicado 2016

Effective connectivity of the subthalamic nucleus–globus pallidus network during Parkinsonian oscillations

por Nevado-Holgado, Alejo J, Mallet, Nicolas, Magill, Peter J, Bogacz, Rafal
Publicado 2014

Red blood cell indices and anaemia as causative factors for cognitive function deficits and for Alzheimer’s disease

por Winchester, Laura M., Powell, John, Lovestone, Simon, Nevado-Holgado, Alejo J.
Publicado 2018

Commonly prescribed drugs associate with cognitive function: a cross-sectional study in UK Biobank

por Nevado-Holgado, Alejo J, Kim, Chi-Hun, Winchester, Laura, Gallacher, John, Lovestone, Simon
Publicado 2016

Mental disorders and intimate partner violence perpetrated by men towards women: A Swedish population-based longitudinal study

por Yu, Rongqin, Nevado-Holgado, Alejo J., Molero, Yasmina, D’Onofrio, Brian M., Larsson, Henrik, Howard, Louise M., Fazel, Seena
Publicado 2019

Associations Between Brain Volumes and Cognitive Tests with Hypertensive Burden in UK Biobank

por Newby, Danielle, Winchester, Laura, Sproviero, William, Fernandes, Marco, Wang, Dai, Kormilitzin, Andrey, Launer, Lenore J., Nevado-Holgado, Alejo J.
Publicado 2021

The relationship between isolated hypertension with brain volumes in UK Biobank

por Newby, Danielle, Winchester, Laura, Sproviero, William, Fernandes, Marco, Ghose, Upamanyu, Lyall, Donald, Launer, Lenore J., Nevado‐Holgado, Alejo J.
Publicado 2022

Genetic and Real-World Clinical Data, Combined with Empirical Validation, Nominate Jak-Stat Signaling as a Target for Alzheimer’s Disease Therapeutic Development

por Nevado-Holgado, Alejo J., Ribe, Elena, Thei, Laura, Furlong, Laura, Mayer, Miguel-Angel, Quan, Jie, Richardson, Jill C., Cavanagh, Jonathan, Lovestone, Simon
Publicado 2019

Validation of UK Biobank data for mental health outcomes: A pilot study using secondary care electronic health records

por Li, Zhenpeng, Kormilitzin, Andrey, Fernandes, Marco, Vaci, Nemanja, Liu, Qiang, Newby, Danielle, Goodday, Sarah, Smith, Tanya, Nevado-Holgado, Alejo J, Winchester, Laura
Publicado 2022

Cross-sectional and longitudinal analyses of outdoor air pollution exposure and cognitive function in UK Biobank

por Cullen, Breda, Newby, Danielle, Lee, Duncan, Lyall, Donald M., Nevado-Holgado, Alejo J., Evans, Jonathan J., Pell, Jill P., Lovestone, Simon, Cavanagh, Jonathan
Publicado 2018

NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology

por Rojo, Ana I., Pajares, Marta, Rada, Patricia, Nuñez, Angel, Nevado-Holgado, Alejo J., Killik, Richard, Van Leuven, Fred, Ribe, Elena, Lovestone, Simon, Yamamoto, Masayuki, Cuadrado, Antonio
Publicado 2017

Comparative effect of metformin versus sulfonylureas with dementia and Parkinson’s disease risk in US patients over 50 with type 2 diabetes mellitus

por Newby, Danielle, Linden, Andrew Brent, Fernandes, Marco, Molero, Yasmina, Winchester, Laura, Sproviero, William, Ghose, Upamanyu, Li, Qingqin S, Launer, Lenore J, van Duijn, Cornelia M, Nevado-Holgado, Alejo J
Publicado 2022

Oscillatory Activity in the Medial Prefrontal Cortex and Nucleus Accumbens Correlates with Impulsivity and Reward Outcome

por Donnelly, Nicholas A., Holtzman, Tahl, Rich, P. Dylan, Nevado-Holgado, Alejo J., Fernando, Anushka B. P., Van Dijck, Gert, Holzhammer, Tobias, Paul, Oliver, Ruther, Patrick, Paulsen, Ole, Robbins, Trevor W., Dalley, Jeffrey W.
Publicado 2014

The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer’s pathology

por Westwood, Sarah, Liu, Benjamine, Baird, Alison L., Anand, Sneha, Nevado-Holgado, Alejo J., Newby, Danielle, Pikkarainen, Maria, Hallikainen, Merja, Kuusisto, Johanna, Streffer, Johannes R., Novak, Gerald, Blennow, Kaj, Andreasson, Ulf, Zetterberg, Henrik, Smith, Ulf, Laakso, Markku, Soininen, Hilkka, Lovestone, Simon
Publicado 2017

Plasma Proteomic Biomarkers Relating to Alzheimer’s Disease: A Meta-Analysis Based on Our Own Studies

por Shi, Liu, Buckley, Noel J., Bos, Isabelle, Engelborghs, Sebastiaan, Sleegers, Kristel, Frisoni, Giovanni B., Wallin, Anders, Lléo, Alberto, Popp, Julius, Martinez-Lage, Pablo, Legido-Quigley, Cristina, Barkhof, Frederik, Zetterberg, Henrik, Visser, Pieter Jelle, Bertram, Lars, Lovestone, Simon, Nevado-Holgado, Alejo J.
Publicado 2021

Methotrexate and relative risk of dementia amongst patients with rheumatoid arthritis: a multi-national multi-database case-control study

por Newby, Danielle, Prieto-Alhambra, Daniel, Duarte-Salles, Talita, Ansell, David, Pedersen, Lars, van der Lei, Johan, Mosseveld, Mees, Rijnbeek, Peter, James, Glen, Alexander, Myriam, Egger, Peter, Podhorna, Jana, Stewart, Robert, Perera, Gayan, Avillach, Paul, Grosdidier, Solène, Lovestone, Simon, Nevado-Holgado, Alejo J.
Publicado 2020

Predicting AT(N) pathologies in Alzheimer’s disease from blood-based proteomic data using neural networks

por Zhang, Yuting, Ghose, Upamanyu, Buckley, Noel J., Engelborghs, Sebastiaan, Sleegers, Kristel, Frisoni, Giovanni B., Wallin, Anders, Lleó, Alberto, Popp, Julius, Martinez-Lage, Pablo, Legido-Quigley, Cristina, Barkhof, Frederik, Zetterberg, Henrik, Visser, Pieter Jelle, Bertram, Lars, Lovestone, Simon, Nevado-Holgado, Alejo J., Shi, Liu
Publicado 2022

Genome‐ and epigenome‐wide studies of plasma protein biomarkers for Alzheimer's disease implicate TBCA and TREM2 in disease risk

por Hillary, Robert F., Gadd, Danni A., McCartney, Daniel L., Shi, Liu, Campbell, Archie, Walker, Rosie M., Ritchie, Craig W., Deary, Ian J., Evans, Kathryn L., Nevado‐Holgado, Alejo J., Hayward, Caroline, Porteous, David J., McIntosh, Andrew M., Lovestone, Simon, Robinson, Matthew R., Marioni, Riccardo E.
Publicado 2022

Identification of plasma proteins relating to brain neurodegeneration and vascular pathology in cognitively normal individuals

por Shi, Liu, Buchanan, Colin R., Cox, Simon R., Hillary, Robert F., Marioni, Riccardo E., Campbell, Archie, Hayward, Caroline, Stolicyn, Aleks, Whalley, Heather C., Harris, Mathew A., Waymont, Jennifer, Waiter, Gordon, Backhouse, Ellen, Wardlaw, Joanna M., Steele, Douglas, Mcintosh, Andrew, Lovestone, Simon, Buckley, Noel J., Nevado‐Holgado, Alejo J.
Publicado 2021

A plasma protein classifier for predicting amyloid burden for preclinical Alzheimer’s disease

por Ashton, Nicholas J., Nevado-Holgado, Alejo J., Barber, Imelda S., Lynham, Steven, Gupta, Veer, Chatterjee, Pratishtha, Goozee, Kathryn, Hone, Eugene, Pedrini, Steve, Blennow, Kaj, Schöll, Michael, Zetterberg, Henrik, Ellis, Kathryn A., Bush, Ashley I., Rowe, Christopher C., Villemagne, Victor L., Ames, David, Masters, Colin L., Aarsland, Dag, Powell, John, Lovestone, Simon, Martins, Ralph, Hye, Abdul
Publicado 2019