Statistical methods for cis‐Mendelian randomization with two‐sample summary‐level data

por Gkatzionis, Apostolos, Burgess, Stephen, Newcombe, Paul J.
Publicado 2022

JAM: A Scalable Bayesian Framework for Joint Analysis of Marginal SNP Effects

por Newcombe, Paul J., Conti, David V., Richardson, Sylvia
Publicado 2016

Fine mapping chromatin contacts in capture Hi-C data

por Eijsbouts, Christiaan Q, Burren, Oliver S, Newcombe, Paul J, Wallace, Chris
Publicado 2019

Two-stage penalized regression screening to detect biomarker-treatment interactions in randomized clinical trials

por Wang, Jixiong, Patel, Ashish, Wason, James M.S., Newcombe, Paul J.
Publicado 2022

Bayesian variable selection with a pleiotropic loss function in Mendelian randomization

por Gkatzionis, Apostolos, Burgess, Stephen, Conti, David V., Newcombe, Paul J.
Publicado 2021

A flexible and parallelizable approach to genome‐wide polygenic risk scores

por Newcombe, Paul J., Nelson, Christopher P., Samani, Nilesh J., Dudbridge, Frank
Publicado 2019

Tailored Bayes: a risk modeling framework under unequal misclassification costs

por Karapanagiotis, Solon, Benedetto, Umberto, Mukherjee, Sach, Kirk, Paul D W, Newcombe, Paul J
Publicado 2021

Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease

por Peters, James E., Lyons, Paul A., Lee, James C., Richard, Arianne C., Fortune, Mary D., Newcombe, Paul J., Richardson, Sylvia, Smith, Kenneth G. C.
Publicado 2016

Homozygous p.Ser267Phe in SLC10A1 is associated with a new type of hypercholanemia and implications for personalized medicine

por Liu, Ruihong, Chen, Chuming, Xia, Xuefeng, Liao, Qijun, Wang, Qiong, Newcombe, Paul J., Xu, Shuhua, Chen, Minghui, Ding, Yue, Li, Xiaoying, Liao, Zhihong, Li, Fucheng, Du, Minlian, Huang, Huaiqiu, Dong, Ruimin, Deng, Weiping, Wang, Ye, Zeng, Binghui, Pan, Qihao, Jiang, Danhua, Zeng, Hao, Sham, Pak, Cao, Yingnan, Maxwell, Patrick H., Gao, Zhi-liang, Peng, Liang, Wang, Yiming
Publicado 2017

GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm

por Bottolo, Leonardo, Chadeau-Hyam, Marc, Hastie, David I., Zeller, Tanja, Liquet, Benoit, Newcombe, Paul, Yengo, Loic, Wild, Philipp S., Schillert, Arne, Ziegler, Andreas, Nielsen, Sune F., Butterworth, Adam S., Ho, Weang Kee, Castagné, Raphaële, Munzel, Thomas, Tregouet, David, Falchi, Mario, Cambien, François, Nordestgaard, Børge G., Fumeron, Fredéric, Tybjærg-Hansen, Anne, Froguel, Philippe, Danesh, John, Petretto, Enrico, Blankenberg, Stefan, Tiret, Laurence, Richardson, Sylvia
Publicado 2013

Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials

por Holmes, Michael V, Newcombe, Paul, Hubacek, Jaroslav A, Sofat, Reecha, Ricketts, Sally L, Cooper, Jackie, Breteler, Monique MB, Bautista, Leonelo E, Sharma, Pankaj, Whittaker, John C, Smeeth, Liam, Fowkes, F Gerald R, Algra, Ale, Shmeleva, Veronika, Szolnoki, Zoltan, Roest, Mark, Linnebank, Michael, Zacho, Jeppe, Nalls, Michael A, Singleton, Andrew B, Ferrucci, Luigi, Hardy, John, Worrall, Bradford B, Rich, Stephen S, Matarin, Mar, Norman, Paul E, Flicker, Leon, Almeida, Osvaldo P, van Bockxmeer, Frank M, Shimokata, Hiroshi, Khaw, Kay-Tee, Wareham, Nicholas J, Bobak, Martin, Sterne, Jonathan AC, Smith, George Davey, Talmud, Philippa J, van Duijn, Cornelia, Humphries, Steve E, Price, Jackie F, Ebrahim, Shah, Lawlor, Debbie A, Hankey, Graeme J, Meschia, James F, Sandhu, Manjinder S, Hingorani, Aroon D, Casas, Juan P
Publicado 2011

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants

por Dadaev, Tokhir, Saunders, Edward J., Newcombe, Paul J., Anokian, Ezequiel, Leongamornlert, Daniel A., Brook, Mark N., Cieza-Borrella, Clara, Mijuskovic, Martina, Wakerell, Sarah, Olama, Ali Amin Al, Schumacher, Fredrick R., Berndt, Sonja I., Benlloch, Sara, Ahmed, Mahbubl, Goh, Chee, Sheng, Xin, Zhang, Zhuo, Muir, Kenneth, Govindasami, Koveela, Lophatananon, Artitaya, Stevens, Victoria L., Gapstur, Susan M., Carter, Brian D., Tangen, Catherine M., Goodman, Phyllis, Thompson, Ian M., Batra, Jyotsna, Chambers, Suzanne, Moya, Leire, Clements, Judith, Horvath, Lisa, Tilley, Wayne, Risbridger, Gail, Gronberg, Henrik, Aly, Markus, Nordström, Tobias, Pharoah, Paul, Pashayan, Nora, Schleutker, Johanna, Tammela, Teuvo L. J., Sipeky, Csilla, Auvinen, Anssi, Albanes, Demetrius, Weinstein, Stephanie, Wolk, Alicja, Hakansson, Niclas, West, Catharine, Dunning, Alison M., Burnet, Neil, Mucci, Lorelei, Giovannucci, Edward, Andriole, Gerald, Cussenot, Olivier, Cancel-Tassin, Géraldine, Koutros, Stella, Freeman, Laura E. Beane, Sorensen, Karina Dalsgaard, Orntoft, Torben Falck, Borre, Michael, Maehle, Lovise, Grindedal, Eli Marie, Neal, David E., Donovan, Jenny L., Hamdy, Freddie C., Martin, Richard M., Travis, Ruth C., Key, Tim J., Hamilton, Robert J., Fleshner, Neil E., Finelli, Antonio, Ingles, Sue Ann, Stern, Mariana C., Rosenstein, Barry, Kerns, Sarah, Ostrer, Harry, Lu, Yong-Jie, Zhang, Hong-Wei, Feng, Ninghan, Mao, Xueying, Guo, Xin, Wang, Guomin, Sun, Zan, Giles, Graham G., Southey, Melissa C., MacInnis, Robert J., FitzGerald, Liesel M., Kibel, Adam S., Drake, Bettina F., Vega, Ana, Gómez-Caamaño, Antonio, Fachal, Laura, Szulkin, Robert, Eklund, Martin, Kogevinas, Manolis, Llorca, Javier, Castaño-Vinyals, Gemma, Penney, Kathryn L., Stampfer, Meir, Park, Jong Y., Sellers, Thomas A., Lin, Hui-Yi, Stanford, Janet L., Cybulski, Cezary, Wokolorczyk, Dominika, Lubinski, Jan, Ostrander, Elaine A., Geybels, Milan S., Nordestgaard, Børge G., Nielsen, Sune F., Weisher, Maren, Bisbjerg, Rasmus, Røder, Martin Andreas, Iversen, Peter, Brenner, Hermann, Cuk, Katarina, Holleczek, Bernd, Maier, Christiane, Luedeke, Manuel, Schnoeller, Thomas, Kim, Jeri, Logothetis, Christopher J., John, Esther M., Teixeira, Manuel R., Paulo, Paula, Cardoso, Marta, Neuhausen, Susan L., Steele, Linda, Ding, Yuan Chun, De Ruyck, Kim, De Meerleer, Gert, Ost, Piet, Razack, Azad, Lim, Jasmine, Teo, Soo-Hwang, Lin, Daniel W., Newcomb, Lisa F., Lessel, Davor, Gamulin, Marija, Kulis, Tomislav, Kaneva, Radka, Usmani, Nawaid, Slavov, Chavdar, Mitev, Vanio, Parliament, Matthew, Singhal, Sandeep, Claessens, Frank, Joniau, Steven, Van den Broeck, Thomas, Larkin, Samantha, Townsend, Paul A., Aukim-Hastie, Claire, Gago-Dominguez, Manuela, Castelao, Jose Esteban, Martinez, Maria Elena, Roobol, Monique J., Jenster, Guido, van Schaik, Ron H. N., Menegaux, Florence, Truong, Thérèse, Koudou, Yves Akoli, Xu, Jianfeng, Khaw, Kay-Tee, Cannon-Albright, Lisa, Pandha, Hardev, Michael, Agnieszka, Kierzek, Andrzej, Thibodeau, Stephen N., McDonnell, Shannon K., Schaid, Daniel J., Lindstrom, Sara, Turman, Constance, Ma, Jing, Hunter, David J., Riboli, Elio, Siddiq, Afshan, Canzian, Federico, Kolonel, Laurence N., Le Marchand, Loic, Hoover, Robert N., Machiela, Mitchell J., Kraft, Peter, Freedman, Matthew, Wiklund, Fredrik, Chanock, Stephen, Henderson, Brian E., Easton, Douglas F., Haiman, Christopher A., Eeles, Rosalind A., Conti, David V., Kote-Jarai, Zsofia
Publicado 2018