Finding mechanisms from metabolic signatures of disease

por Newgard, Christopher B
Publicado 2012

Recent Progress in Metabolic Signaling Pathways Regulating Aging and Life Span

por Newgard, Christopher B., Pessin, Jeffrey E.
Publicado 2014

Remodeling of the Acetylproteome by SIRT3 Manipulation Fails to Affect Insulin Secretion or β Cell Metabolism in the Absence of Overnutrition

por Peterson, Brett S., Campbell, Jonathan E., Ilkayeva, Olga, Grimsrud, Paul A., Hirschey, Matthew D., Newgard, Christopher B.
Publicado 2018

Metabolomics Applied to Diabetes Research: Moving From Information to Knowledge

por Bain, James R., Stevens, Robert D., Wenner, Brett R., Ilkayeva, Olga, Muoio, Deborah M., Newgard, Christopher B.
Publicado 2009

BMI, RQ, Diabetes, and Sex Affect the Relationships Between Amino Acids and Clamp Measures of Insulin Action in Humans

por Thalacker-Mercer, Anna E., Ingram, Katherine H., Guo, Fangjian, Ilkayeva, Olga, Newgard, Christopher B., Garvey, W. Timothy
Publicado 2014

Plasma acylcarnitine profiling indicates increased fatty acid oxidation relative to tricarboxylic acid cycle capacity in young, healthy low birth weight men

por Ribel‐Madsen, Amalie, Ribel‐Madsen, Rasmus, Brøns, Charlotte, Newgard, Christopher B., Vaag, Allan A., Hellgren, Lars I.
Publicado 2016

Plasma amino acid levels are elevated in young, healthy low birth weight men exposed to short‐term high‐fat overfeeding

por Ribel‐Madsen, Amalie, Hellgren, Lars I., Brøns, Charlotte, Ribel‐Madsen, Rasmus, Newgard, Christopher B., Vaag, Allan A.
Publicado 2016

Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival

por Hayes, Heather L., Peterson, Brett S., Haldeman, Jonathan M., Newgard, Christopher B., Hohmeier, Hans E., Stephens, Samuel B.
Publicado 2017

Plasma acylcarnitines are associated with pulmonary hypertension

por Luo, Nancy, Craig, Damian, Ilkayeva, Olga, Muehlbauer, Michael, Kraus, William E., Newgard, Christopher B., Shah, Svati H., Rajagopal, Sudarshan
Publicado 2017

Identification of a small molecule that stimulates human β-cell proliferation and insulin secretion, and protects against cytotoxic stress in rat insulinoma cells

por Hohmeier, Hans E., Zhang, Lu, Taylor, Brandon, Stephens, Samuel, Lu, Danhong, McNamara, Peter, Laffitte, Bryan, Newgard, Christopher B.
Publicado 2020

Insulin action, type 2 diabetes, and branched-chain amino acids: A two-way street

por White, Phillip J., McGarrah, Robert W., Herman, Mark A., Bain, James R., Shah, Svati H., Newgard, Christopher B.
Publicado 2021

Dissecting the in Vivo Metabolic Potential of Two Human Gut Acetogens

por Rey, Federico E., Faith, Jeremiah J., Bain, James, Muehlbauer, Michael J., Stevens, Robert D., Newgard, Christopher B., Gordon, Jeffrey I.
Publicado 2010

Effect of Roux-en-Y Gastric Bypass and Laparoscopic Adjustable Gastric Banding on Branched-Chain Amino Acid Metabolism

por Magkos, Faidon, Bradley, David, Schweitzer, George G., Finck, Brian N., Eagon, J. Christopher, Ilkayeva, Olga, Newgard, Christopher B., Klein, Samuel
Publicado 2013

Effect of Progressive Weight Loss on Lactate Metabolism: a Randomized Controlled Trial

por Chondronikola, Maria, Magkos, Faidon, Yoshino, Jun, Okunade, Adewole L., Patterson, Bruce W., Muehlbauer, Michael J., Newgard, Christopher B., Klein, Samuel
Publicado 2018

Restoration of Hepatic Glucokinase Expression Corrects Hepatic Glucose Flux and Normalizes Plasma Glucose in Zucker Diabetic Fatty Rats

por Torres, Tracy P., Catlin, ReEtta L., Chan, Robert, Fujimoto, Yuka, Sasaki, Noriyasu, Printz, Richard L., Newgard, Christopher B., Shiota, Masakazu
Publicado 2009

Recommendations for Improving Identification and Quantification in Non-Targeted, GC-MS-Based Metabolomic Profiling of Human Plasma

por Wang, Hanghang, Muehlbauer, Michael J., O’Neal, Sara K., Newgard, Christopher B., Hauser, Elizabeth R., Bain, James R., Shah, Svati H.
Publicado 2017

Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing

por Haldeman, Jonathan M, Conway, Amanda E, Arlotto, Michelle E, Slentz, Dorothy H, Muoio, Deborah M, Becker, Thomas C, Newgard, Christopher B
Publicado 2019

Cafeteria Diet Is a Robust Model of Human Metabolic Syndrome With Liver and Adipose Inflammation: Comparison to High-Fat Diet

por Sampey, Brante P., Vanhoose, Amanda M., Winfield, Helena M., Freemerman, Alex J., Muehlbauer, Michael J., Fueger, Patrick T., Newgard, Christopher B., Makowski, Liza
Publicado 2011

Cardiomyocyte glucagon receptor signaling modulates outcomes in mice with experimental myocardial infarction

por Ali, Safina, Ussher, John R., Baggio, Laurie L., Kabir, M. Golam, Charron, Maureen J., Ilkayeva, Olga, Newgard, Christopher B., Drucker, Daniel J.
Publicado 2014

Type-2-Diabetes Alters CSF but Not Plasma Metabolomic and AD Risk Profiles in Vervet Monkeys

por Kavanagh, Kylie, Day, Stephen M., Pait, Morgan C., Mortiz, William R., Newgard, Christopher B., Ilkayeva, Olga, Mcclain, Donald A., Macauley, Shannon L.
Publicado 2019