Neuronal Apolipoprotein E4 Expression Results in Proteome-Wide Alterations and Compromises Bioenergetic Capacity by Disrupting Mitochondrial Function

por Orr, Adam L., Kim, Chaeyoung, Jimenez-Morales, David, Newton, Billy W., Johnson, Jeffrey R., Krogan, Nevan J., Swaney, Danielle L., Mahley, Robert W.
Publicado 2019

The Yeast DNA Damage Checkpoint Kinase Rad53 Targets the Exoribonuclease, Xrn1

por Lao, Jessica P., Ulrich, Katie M., Johnson, Jeffrey R., Newton, Billy W., Vashisht, Ajay A., Wohlschlegel, James A., Krogan, Nevan J., Toczyski, David P.
Publicado 2018

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation

por Faust, Tyler B, Li, Yang, Bacon, Curtis W, Jang, Gwendolyn M, Weiss, Amit, Jayaraman, Bhargavi, Newton, Billy W, Krogan, Nevan J, D'Orso, Iván, Frankel, Alan D
Publicado 2018

Endosomal cAMP production broadly impacts the cellular phosphoproteome

por Tsvetanova, Nikoleta G., Trester-Zedlitz, Michelle, Newton, Billy W., Peng, Grace E., Johnson, Jeffrey R., Jimenez-Morales, David, Kurland, Andrew P., Krogan, Nevan J., von Zastrow, Mark
Publicado 2021

Identification of Antiviral Roles for the Exon-Junction Complex and Nonsense-Mediated Decay in Flaviviral Infection

por Li, Minghua, Johnson, Jeffrey R., Truong, Billy, Kim, Grace, Weinbren, Nathan, Dittmar, Mark, Shah, Priya S., Von Dollen, John, Newton, Billy W., Jang, Gwendolyn M., Krogan, Nevan J., Cherry, Sara, Ramage, Holly
Publicado 2019

Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response

por Sidrauski, Carmela, Tsai, Jordan C, Kampmann, Martin, Hearn, Brian R, Vedantham, Punitha, Jaishankar, Priyadarshini, Sokabe, Masaaki, Mendez, Aaron S, Newton, Billy W, Tang, Edward L, Verschueren, Erik, Johnson, Jeffrey R, Krogan, Nevan J, Fraser, Christopher S, Weissman, Jonathan S, Renslo, Adam R, Walter, Peter
Publicado 2015

Quantitative Proteomic Analysis Reveals apoE4-Dependent Phosphorylation of the Actin-Regulating Protein VASP

por Cakir, Zeynep, Lord, Samuel J., Zhou, Yuan, Jang, Gwendolyn M., Polacco, Benjamin J., Eckhardt, Manon, Jimenez-Morales, David, Newton, Billy W., Orr, Adam L., Johnson, Jeffrey R., da Cruz, Alexandre, Mullins, R. Dyche, Krogan, Nevan J., Mahley, Robert W., Swaney, Danielle L.
Publicado 2023

Global post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling

por Johnson, Jeffrey R., Crosby, David C., Hultquist, Judd F., Kurland, Andrew P., Adhikary, Prithy, Li, Donna, Marlett, John, Swann, Justine, Hüttenhain, Ruth, Verschueren, Erik, Johnson, Tasha L., Newton, Billy W., Shales, Michael, Simon, Viviana A., Beltrao, Pedro, Frankel, Alan D., Marson, Alexander, Cox, Jeffery S., Fregoso, Oliver I., Young, John A.T., Krogan, Nevan J.
Publicado 2022

Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets

por Haas, Kelsey M., McGregor, Michael J., Bouhaddou, Mehdi, Polacco, Benjamin J., Kim, Eun-Young, Nguyen, Thong T., Newton, Billy W., Urbanowski, Matthew, Kim, Heejin, Williams, Michael A. P., Rezelj, Veronica V., Hardy, Alexandra, Fossati, Andrea, Stevenson, Erica J., Sukerman, Ellie, Kim, Tiffany, Penugonda, Sudhir, Moreno, Elena, Braberg, Hannes, Zhou, Yuan, Metreveli, Giorgi, Harjai, Bhavya, Tummino, Tia A., Melnyk, James E., Soucheray, Margaret, Batra, Jyoti, Pache, Lars, Martin-Sancho, Laura, Carlson-Stevermer, Jared, Jureka, Alexander S., Basler, Christopher F., Shokat, Kevan M., Shoichet, Brian K., Shriver, Leah P., Johnson, Jeffrey R., Shaw, Megan L., Chanda, Sumit K., Roden, Dan M., Carter, Tonia C., Kottyan, Leah C., Chisholm, Rex L., Pacheco, Jennifer A., Smith, Maureen E., Schrodi, Steven J., Albrecht, Randy A., Vignuzzi, Marco, Zuliani-Alvarez, Lorena, Swaney, Danielle L., Eckhardt, Manon, Wolinsky, Steven M., White, Kris M., Hultquist, Judd F., Kaake, Robyn M., García-Sastre, Adolfo, Krogan, Nevan J.
Publicado 2023