High-content imaging as a tool to quantify and characterize malaria parasites

por Rosenthal, Melissa R., Ng, Caroline L.
Publicado 2023

No Evidence of Decreased Artemisinin Efficacy in a High-Transmission Malaria Setting in Mali

por Ng, Caroline L., Fidock, David A.
Publicado 2012

Repurposing Quinoline and Artemisinin Antimalarials as Therapeutics for SARS-CoV-2: Rationale and Implications

por Firestone, Tessa M., Oyewole, Opeoluwa O., Reid, St Patrick, Ng, Caroline L.
Publicado 2021

Immuno-epidemiology and pathophysiology of coronavirus disease 2019 (COVID-19)

por Olwenyi, Omalla A., Dyavar, Shetty Ravi, Acharya, Arpan, Podany, Anthony T., Fletcher, Courtney V., Ng, Caroline L., Reid, St Patrick, Byrareddy, Siddappa N.
Publicado 2020

Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents

por Stokes, Barbara H., Yoo, Euna, Murithi, James M., Luth, Madeline R., Afanasyev, Pavel, da Fonseca, Paula C. A., Winzeler, Elizabeth A., Ng, Caroline L., Bogyo, Matthew, Fidock, David A.
Publicado 2019

Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study

por McCarthy, James S, Lotharius, Julie, Rückle, Thomas, Chalon, Stephan, Phillips, Margaret A, Elliott, Suzanne, Sekuloski, Silvana, Griffin, Paul, Ng, Caroline L, Fidock, David A, Marquart, Louise, Williams, Noelle S, Gobeau, Nathalie, Bebrevska, Lidiya, Rosario, Maria, Marsh, Kennan, Möhrle, Jörg J
Publicado 2017

A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue

por Sonoiki, Ebere, Ng, Caroline L., Lee, Marcus C. S., Guo, Denghui, Zhang, Yong-Kang, Zhou, Yasheen, Alley, M. R. K., Ahyong, Vida, Sanz, Laura M., Lafuente-Monasterio, Maria Jose, Dong, Chen, Schupp, Patrick G., Gut, Jiri, Legac, Jenny, Cooper, Roland A., Gamo, Francisco-Javier, DeRisi, Joseph, Freund, Yvonne R., Fidock, David A., Rosenthal, Philip J.
Publicado 2017

Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax mal...

por Llanos-Cuentas, Alejandro, Casapia, Martin, Chuquiyauri, Raúl, Hinojosa, Juan-Carlos, Kerr, Nicola, Rosario, Maria, Toovey, Stephen, Arch, Robert H, Phillips, Margaret A, Rozenberg, Felix D, Bath, Jade, Ng, Caroline L, Cowell, Annie N, Winzeler, Elizabeth A, Fidock, David A, Baker, Mark, Möhrle, Jörg J, Hooft van Huijsduijnen, Rob, Gobeau, Nathalie, Araeipour, Nada, Andenmatten, Nicole, Rückle, Thomas, Duparc, Stephan
Publicado 2018

Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome

por Deni, Ioanna, Stokes, Barbara H., Ward, Kurt E., Fairhurst, Kate J., Pasaje, Charisse Flerida A., Yeo, Tomas, Akbar, Shirin, Park, Heekuk, Muir, Ryan, Bick, Daniella S., Zhan, Wenhu, Zhang, Hao, Liu, Yi Jing, Ng, Caroline L., Kirkman, Laura A., Almaliti, Jehad, Gould, Alexandra E., Duffey, Maëlle, O'Donoghue, Anthony J., Uhlemann, Anne-Catrin, Niles, Jacquin C., da Fonseca, Paula C.A., Gerwick, William H., Lin, Gang, Bogyo, Matthew, Fidock, David A.
Publicado 2023

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling

por Le Bihan, Amélie, de Kanter, Ruben, Angulo-Barturen, Iñigo, Binkert, Christoph, Boss, Christoph, Brun, Reto, Brunner, Ralf, Buchmann, Stephan, Burrows, Jeremy, Dechering, Koen J., Delves, Michael, Ewerling, Sonja, Ferrer, Santiago, Fischli, Christoph, Gamo–Benito, Francisco Javier, Gnädig, Nina F., Heidmann, Bibia, Jiménez-Díaz, María Belén, Leroy, Didier, Martínez, Maria Santos, Meyer, Solange, Moehrle, Joerg J., Ng, Caroline L., Noviyanti, Rintis, Ruecker, Andrea, Sanz, Laura María, Sauerwein, Robert W., Scheurer, Christian, Schleiferboeck, Sarah, Sinden, Robert, Snyder, Christopher, Straimer, Judith, Wirjanata, Grennady, Marfurt, Jutta, Price, Ric N., Weller, Thomas, Fischli, Walter, Fidock, David A., Clozel, Martine, Wittlin, Sergio
Publicado 2016