Circulating Tumor DNA Mutations in Progressive Gastrointestinal Stromal Tumors Identify Biomarkers of Treatment Resistance and Uncover Potential Therapeutic Strategies

por Ko, Tun Kiat, Lee, Elizabeth, Ng, Cedric Chuan-Young, Yang, Valerie Shiwen, Farid, Mohamad, Teh, Bin Tean, Chan, Jason Yongsheng, Somasundaram, Nagavalli
Publicado 2022

The Multi-Dimensional Biomarker Landscape in Cancer Immunotherapy

por Lee, Jing Yi, Kannan, Bavani, Lim, Boon Yee, Li, Zhimei, Lim, Abner Herbert, Loh, Jui Wan, Ko, Tun Kiat, Ng, Cedric Chuan-Young, Chan, Jason Yongsheng
Publicado 2022

Bizarre giant cells in human angiosarcoma exhibit chemoresistance and contribute to poor survival outcomes

por Tan, Grace Fangmin, Goh, Shane, Lim, Abner Herbert, Liu, Wei, Lee, Jing Yi, Rajasegaran, Vikneswari, Sam, Xin Xiu, Tay, Timothy Kwang Yong, Selvarajan, Sathiyamoorthy, Ng, Cedric Chuan‐Young, Teh, Bin Tean, Chan, Jason Yongsheng
Publicado 2020

Multiregion sequencing of sarcomatoid renal cell carcinoma arising from autosomal dominant polycystic kidney disease

por Lee, Elizabeth, Guan, Peiyong, Lim, Abner Herbert, Loh, Jui Wan, Tan, Grace Fangmin, Loh, Tracy, Ng, Dave Yong Xiang, Lee, Jing Yi, Goh, Shane, Liu, Wei, Ng, Cedric Chuan‐Young, Teh, Bin Tean, Chan, Jason Yongsheng
Publicado 2022

Genome assembly and chemogenomic profiling of National Flower of Singapore Papilionanthe Miss Joaquim ‘Agnes’ reveals metabolic pathways regulating floral traits

por Lim, Abner Herbert, Low, Zhen Jie, Shingate, Prashant Narendra, Hong, Jing Han, Chong, Shu Chen, Ng, Cedric Chuan Young, Liu, Wei, Vaser, Robert, Šikić, Mile, Sung, Wing-Kin Ken, Nagarajan, Niranjan, Tan, Patrick, Teh, Bin Tean
Publicado 2022

Rare Occurrence of Aristolochic Acid Mutational Signatures in Oro-Gastrointestinal Tract Cancers

por Lim, Abner Herbert, Chan, Jason Yongsheng, Yu, Ming-Chin, Wu, Tsung-Han, Hong, Jing Han, Ng, Cedric Chuan Young, Low, Zhen Jie, Liu, Wei, Vikneswari, Rajasegaran, Sung, Pin-Cheng, Fan, Wen-Lang, Teh, Bin Tean, Hsieh, Sen-Yung
Publicado 2022

Clinical implications of systemic and local immune responses in human angiosarcoma

por Chan, Jason Yongsheng, Tan, Grace Fangmin, Yeong, Joe, Ong, Chee Wee, Ng, Dave Yong Xiang, Lee, Elizabeth, Koh, Joanna, Ng, Cedric Chuan-Young, Lee, Jing Yi, Liu, Wei, Wong, Ru Xin, Ong, Chin-Ann Johnny, Farid, Mohamad, Teh, Bin Tean, Soo, Khee Chee
Publicado 2021

Lack of Targetable FGFR2 Fusions in Endemic Fluke-Associated Cholangiocarcinoma

por Kongpetch, Sarinya, Jusakul, Apinya, Lim, Jing Quan, Ng, Cedric Chuan Young, Chan, Jason Yongsheng, Rajasegaran, Vikneswari, Lim, Tse Hui, Lim, Kiat Hon, Choo, Su Pin, Dima, Simona, Popescu, Irinel, Duda, Dan G., Kukongviriyapan, Veerapol, Khuntikeo, Narong, Pairojkul, Chawalit, Rozen, Steven G., Tan, Patrick, Teh, Bin Tean
Publicado 2020

Spatial transcriptomics reveal topological immune landscapes of Asian head and neck angiosarcoma

por Loh, Jui Wan, Lee, Jing Yi, Lim, Abner Herbert, Guan, Peiyong, Lim, Boon Yee, Kannan, Bavani, Lee, Elizabeth Chun Yong, Gu, Ning Xin, Ko, Tun Kiat, Ng, Cedric Chuan-Young, Lim, Jeffrey Chun Tatt, Yeong, Joe, Lim, Jing Quan, Ong, Choon Kiat, Teh, Bin Tean, Chan, Jason Yongsheng
Publicado 2023

A comprehensive next generation sequencing tissue assay for Asian-prevalent cancers—Analytical validation and performance evaluation with clinical samples

por Ng, Cedric Chuan-Young, Lim, Sandy, Lim, Abner Herbert, Md Nasir, Nur Diyana, Zhang, Jingxian, Rajasegaran, Vikneswari, Lee, Jing Yi, Kok, Jessica Sook Ting, Thike, Aye Aye, Lim, Johnathan Xiande, Weng, Ruifen, Yee, Sidney, Choudhury, Yukti, Chan, Jason Yongsheng, Tan, Puay Hoon, Tan, Min-Han, Teh, Bin Tean
Publicado 2022

Whole‐exome sequencing of breast cancer, malignant peripheral nerve sheath tumor and neurofibroma from a patient with neurofibromatosis type 1

por McPherson, John Richard, Ong, Choon‐Kiat, Ng, Cedric Chuan‐Young, Rajasegaran, Vikneswari, Heng, Hong‐Lee, Yu, Willie Shun‐Shing, Tan, Benita Kiat‐Tee, Madhukumar, Preetha, Teo, Melissa Ching‐Ching, Ngeow, Joanne, Thike, Aye‐Aye, Rozen, Steven George, Tan, Puay‐Hoon, Lee, Ann Siew‐Gek, Teh, Bin‐Tean, Yap, Yoon‐Sim
Publicado 2015

Machine-learning model derived gene signature predictive of paclitaxel survival benefit in gastric cancer: results from the randomised phase III SAMIT trial

por Sundar, Raghav, Barr Kumarakulasinghe, Nesaretnam, Huak Chan, Yiong, Yoshida, Kazuhiro, Yoshikawa, Takaki, Miyagi, Yohei, Rino, Yasushi, Masuda, Munetaka, Guan, Jia, Sakamoto, Junichi, Tanaka, Shiro, Tan, Angie Lay-Keng, Hoppe, Michal Marek, Jeyasekharan, Anand D., Ng, Cedric Chuan Young, De Simone, Mark, Grabsch, Heike I., Lee, Jeeyun, Oshima, Takashi, Tsuburaya, Akira, Tan, Patrick
Publicado 2022

A novel genomic panel as an adjunctive diagnostic tool for the characterization and profiling of breast Fibroepithelial lesions

por Sim, Yirong, Ng, Gwendolene Xin Pei, Ng, Cedric Chuan Young, Rajasegaran, Vikneswari, Wong, Suet Far, Liu, Wei, Guan, Peiyong, Nagarajan, Sanjanaa, Ng, Wai Yee, Thike, Aye Aye, Lim, Jeffrey Chun Tatt, Nasir, Nur Diyana Binte Md, Tan, Veronique Kiak Mien, Madhukumar, Preetha, Yong, Wei Sean, Wong, Chow Yin, Tan, Benita Kiat Tee, Ong, Kong Wee, Teh, Bin Tean, Tan, Puay Hoon
Publicado 2019

Therapeutic and immunomodulatory potential of pazopanib in malignant phyllodes tumor

por Ng, Dave Yong Xiang, Li, Zhimei, Lee, Elizabeth, Kok, Jessica Sook Ting, Lee, Jing Yi, Koh, Joanna, Ng, Cedric Chuan-Young, Lim, Abner Herbert, Liu, Wei, Ng, Sheng Rong, Lim, Kah Suan, Huang, Xi Xiao, Hong, Jing Han, Guan, Peiyong, Sim, Yirong, Thike, Aye Aye, Nasir, Nur Diyana Md, Li, Shang, Tan, Puay Hoon, Teh, Bin Tean, Chan, Jason Yongsheng
Publicado 2022

Case report: Understanding the impact of persistent tissue-localization of SARS-CoV-2 on immune response activity via spatial transcriptomic analysis of two cancer patients with CO...

por Lau, Mai Chan, Yi, Yang, Goh, Denise, Cheung, Chun Chau Lawrence, Tan, Benedict, Lim, Jeffrey Chun Tatt, Joseph, Craig Ryan, Wee, Felicia, Lee, Justina Nadia, Lim, Xinru, Lim, Chun Jye, Leow, Wei Qiang, Lee, Jing Yi, Ng, Cedric Chuan Young, Bashiri, Hamed, Cheow, Peng Chung, Chan, Chun Yip, Koh, Ye Xin, Tan, Thuan Tong, Kalimuddin, Shirin, Tai, Wai Meng David, Ng, Jia Lin, Low, Jenny Guek-Hong, Lim, Tony Kiat Hon, Liu, Jin, Yeong, Joe Poh Sheng
Publicado 2022

Epigenetic promoter alterations in GI tumour immune-editing and resistance to immune checkpoint inhibition

por Sundar, Raghav, Huang, Kie-Kyon, Kumar, Vikrant, Ramnarayanan, Kalpana, Demircioglu, Deniz, Her, Zhisheng, Ong, Xuewen, Bin Adam Isa, Zul Fazreen, Xing, Manjie, Tan, Angie Lay-Keng, Tai, David Wai Meng, Choo, Su Pin, Zhai, Weiwei, Lim, Jia Qi, Das Thakur, Meghna, Molinero, Luciana, Cha, Edward, Fasso, Marcella, Niger, Monica, Pietrantonio, Filippo, Lee, Jeeyun, Jeyasekharan, Anand D, Qamra, Aditi, Patnala, Radhika, Fabritius, Arne, De Simone, Mark, Yeong, Joe, Ng, Cedric Chuan Young, Rha, Sun Young, Narita, Yukiya, Muro, Kei, Guo, Yu Amanda, Skanderup, Anders Jacobsen, So, Jimmy Bok Yan, Yong, Wei Peng, Chen, Qingfeng, Göke, Jonathan, Tan, Patrick
Publicado 2022

Whole-genome sequencing identifies responders to Pembrolizumab in relapse/refractory natural-killer/T cell lymphoma

por Lim, Jing Quan, Huang, Dachuan, Tang, Tiffany, Tan, Daryl, Laurensia, Yurike, Peng, Rou-Jun, Wong, Esther Kam Yin, Cheah, Daryl Ming Zhe, Chia, Burton Kuan Hui, Iqbal, Jabed, Grigoropoulos, Nicholas Francis, Nairismägi, Maarja-Liisa, Ng, Cedric Chuan Young, Rajasegaran, Vikneswari, Hong, Huangming, Kim, Seok Jin, Cho, Junhun, Tse, Eric, Mow, Benjamin, Cai, Qi-Chun, Poon, Li-Mei, Cai, Qing-qing, Tan, Jing, Chan, Jason Yongsheng, Lim, Johnathan Xiande, Goh, Yeow Tee, Phipps, Colin, Rötzschke, Olaf, Cheng, Chee Leong, Ha, Jeslin Chian Hung, Khoo, Lay Poh, Loh, Yvonne Su Ming, Au-Yeung, Rex, Chan, Thomas Sau-Yan, Kwong, Yok-Lam, Hwang, William, Kim, Won Seog, Bei, Jin-Xin, Lin, Tongyu, Ong, Choon Kiat, Lim, Soon Thye
Publicado 2020