Binding and structural asymmetry governs ligand sensitivity in a cyclic nucleotide–gated ion channel

por Ng, Leo C.T., Zhuang, Meiying, Van Petegem, Filip, Li, Yue Xian, Accili, Eric A.
Publicado 2019

Molecular dysregulation of ciliary polycystin-2 channels caused by variants in the TOP domain

por Vien, Thuy N., Wang, Jinliang, Ng, Leo C. T., Cao, Erhu, DeCaen, Paul G.
Publicado 2020

A tamoxifen receptor within a voltage-gated sodium channel

por Sula, Altin, Hollingworth, David, Ng, Leo C.T., Larmore, Megan, DeCaen, Paul G., Wallace, B.A.
Publicado 2021

The complete structure of an activated open sodium channel

por Sula, Altin, Booker, Jennifer, Ng, Leo C. T., Naylor, Claire E., DeCaen, Paul G., Wallace, B. A.
Publicado 2017

Disrupting polycystin-2 EF hand Ca(2+) affinity does not alter channel function or contribute to polycystic kidney disease

por Vien, Thuy N., Ng, Leo C. T., Smith, Jessica M., Dong, Ke, Krappitz, Matteus, Gainullin, Vladimir G., Fedeles, Sorin, Harris, Peter C., Somlo, Stefan, DeCaen, Paul G.
Publicado 2020