Fungal Endophytes: A Promising Frontier for Discovery of Novel Bioactive Compounds

por Gakuubi, Martin Muthee, Munusamy, Madhaiyan, Liang, Zhao-Xun, Ng, Siew Bee
Publicado 2021

Diversity and Biosynthetic Potential of Fungi Isolated from St. John’s Island, Singapore

por Munusamy, Madhaiyan, Tan, Kenneth, Nge, Choy Eng, Gakuubi, Martin Muthee, Crasta, Sharon, Kanagasundaram, Yoganathan, Ng, Siew Bee
Publicado 2023

Enhancing the Discovery of Bioactive Secondary Metabolites From Fungal Endophytes Using Chemical Elicitation and Variation of Fermentation Media

por Gakuubi, Martin Muthee, Ching, Kuan Chieh, Munusamy, Madhaiyan, Wibowo, Mario, Liang, Zhao-Xun, Kanagasundaram, Yoganathan, Ng, Siew Bee
Publicado 2022

Enhancing armeniaspirols production through multi-level engineering of a native Streptomyces producer

por Heng, Elena, Lim, Yi Wee, Leong, Chung Yan, Ng, Veronica W. P., Ng, Siew Bee, Lim, Yee Hwee, Wong, Fong Tian
Publicado 2023

Isolation and Identification of an Anthracimycin Analogue from Nocardiopsis kunsanensis, a Halophile from a Saltern, by Genomic Mining Strategy

por Sirota, Fernanda L., Goh, Falicia, Low, Kia-Ngee, Yang, Lay-Kien, Crasta, Sharon C., Eisenhaber, Birgit, Eisenhaber, Frank, Kanagasundaram, Yoganathan, Ng, Siew Bee
Publicado 2018

In-Silico Identified New Natural Sortase A Inhibitors Disrupt S. aureus Biofilm Formation

por Thappeta, Kishore Reddy Venkata, Zhao, Li Na, Nge, Choy Eng, Crasta, Sharon, Leong, Chung Yan, Ng, Veronica, Kanagasundaram, Yoganathan, Fan, Hao, Ng, Siew Bee
Publicado 2020

CRISPR/Cas9 RNP-assisted validation of palmarumycin biosynthetic gene cluster in Lophiotrema sp. F6932

por Gakuubi, Martin Muthee, Ching, Kuan Chieh, Munusamy, Madhaiyan, Wibowo, Mario, Lim, Chun Teck, Ma, Guang-Lei, Liang, Zhao-Xun, Kanagasundaram, Yoganathan, Ng, Siew Bee
Publicado 2022

Chemical elicitation as an avenue for discovery of bioactive compounds from fungal endophytes

por Munusamy, Madhaiyan, Ching, Kuan Chieh, Yang, Lay Kien, Crasta, Sharon, Gakuubi, Martin Muthee, Chee, Zhao Yan, Wibowo, Mario, Leong, Chung Yan, Kanagasundaram, Yoganathan, Ng, Siew Bee
Publicado 2022

Antibacterial Spirotetronate Polyketides from an Actinomadura sp. Strain A30804

por Ching, Kuan-Chieh, Chin, Elaine J., Wibowo, Mario, Tan, Zann Y., Yang, Lay-Kien, Seow, Deborah C., Leong, Chung-Yan, Ng, Veronica W., Ng, Siew-Bee, Kanagasundaram, Yoganathan
Publicado 2022

Antibacterial Thiopeptide GE2270-Congeners from Nonomuraea jiangxiensis

por Ching, Kuan-Chieh, Chin, Elaine J., Wibowo, Mario, Tan, Zann Y., Yang, Lay-Kien, Seow, Deborah C., Leong, Chung-Yan, Ng, Veronica W., Ng, Siew-Bee, Kanagasundaram, Yoganathan
Publicado 2022

Natural Products from Singapore Soil-Derived Streptomycetaceae Family and Evaluation of Their Biological Activities

por Chin, Elaine-Jinfeng, Ching, Kuan-Chieh, Tan, Zann Y., Wibowo, Mario, Leong, Chung-Yan, Yang, Lay-Kien, Ng, Veronica W. P., Seow, Deborah C. S., Kanagasundaram, Yoganathan, Ng, Siew-Bee
Publicado 2023

Hypoculoside, a sphingoid base-like compound from Acremonium disrupts the membrane integrity of yeast cells

por Alfatah, Mohammad, Wong, Jin Huei, Nge, Choy Eng, Kong, Kiat Whye, Low, Kia Ngee, Leong, Chung Yan, Crasta, Sharon, Munusamy, Madhaiyan, Chang, Amanda Mun Leng, Hoon, Shawn, Ng, Siew Bee, Kanagasundaram, Yoganathan, Arumugam, Prakash
Publicado 2019

Genomics-driven discovery of a biosynthetic gene cluster required for the synthesis of BII-Rafflesfungin from the fungus Phoma sp. F3723

por Sinha, Swati, Nge, Choy-Eng, Leong, Chung Yan, Ng, Veronica, Crasta, Sharon, Alfatah, Mohammad, Goh, Falicia, Low, Kia-Ngee, Zhang, Huibin, Arumugam, Prakash, Lezhava, Alexander, Chen, Swaine L., Kanagasundaram, Yoganathan, Ng, Siew Bee, Eisenhaber, Frank, Eisenhaber, Birgit
Publicado 2019

Identification and engineering of 32 membered antifungal macrolactone notonesomycins

por Goh, Falicia, Zhang, Mingzi M., Lim, Tian Ru, Low, Kia Ngee, Nge, Choy Eng, Heng, Elena, Yeo, Wan Lin, Sirota, Fernanda L., Crasta, Sharon, Tan, Zann, Ng, Veronica, Leong, Chung Yan, Zhang, Huibin, Lezhava, Alexander, Chen, Swaine L., Hoon, Shawn S., Eisenhaber, Frank, Eisenhaber, Birgit, Kanagasundaram, Yoganathan, Wong, Fong T., Ng, Siew Bee
Publicado 2020