Membrane constriction and thinning by sequential ESCRT-III polymerization

por Nguyen, Henry C., Talledge, Nathaniel, McCullough, John, Sharma, Abhimanyu, Moss, Frank R., Iwasa, Janet H., Vershinin, Michael D., Sundquist, Wesley I., Frost, Adam
Publicado 2020

Crystal structure of monkeypox H1 phosphatase, an antiviral drug target

por Cui, Wen, Huang, Haojun, Duan, Yinkai, Luo, Zhi, Wang, Haofeng, Zhang, Tenan, Nguyen, Henry C, Shen, Wei, Su, Dan, Li, Xi, Ji, Xiaoyun, Yang, Haitao, Wang, Wei
Publicado 2022

Shared functions of plant and mammalian StAR-related lipid transfer (START) domains in modulating transcription factor activity

por Schrick, Kathrin, Bruno, Michael, Khosla, Aashima, Cox, Paige N, Marlatt, Sara A, Roque, Remigio A, Nguyen, Henry C, He, Cuiwen, Snyder, Michael P, Singh, Daljit, Yadav, Gitanjali
Publicado 2014

FBXO32, encoding a member of the SCF complex, is mutated in dilated cardiomyopathy

por Al-Yacoub, Nadya, Shaheen, Ranad, Awad, Salma Mahmoud, Kunhi, Muhammad, Dzimiri, Nduna, Nguyen, Henry C., Xiong, Yong, Al-Buraiki, Jehad, Al-Habeeb, Waleed, Alkuraya, Fowzan S., Poizat, Coralie
Publicado 2016

Structural basis of antagonism of human APOBEC3F by HIV-1 Vif

por Hu, Yingxia, Desimmie, Belete A., Nguyen, Henry C., Ziegler, Samantha J., Cheng, Tat Cheung, Chen, John, Wang, Jia, Wang, Hongwei, Zhang, Kai, Pathak, Vinay K., Xiong, Yong
Publicado 2019

Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants

por Guo, Hangtian, Yang, Yixuan, Zhao, Tiantian, Lu, Yuchi, Gao, Yan, Li, Tinghan, Xiao, Hang, Chu, Xiaoyu, Zheng, Le, Li, Wanting, Cheng, Hao, Huang, Haibin, Liu, Yang, Lou, Yang, Nguyen, Henry C., Wu, Chao, Chen, Yuxin, Yang, Haitao, Ji, Xiaoyun
Publicado 2023

Structures of Omicron spike complexes and implications for neutralizing antibody development

por Guo, Hangtian, Gao, Yan, Li, Tinghan, Li, Tingting, Lu, Yuchi, Zheng, Le, Liu, Yue, Yang, Tingting, Luo, Feiyang, Song, Shuyi, Wang, Wei, Yang, Xiuna, Nguyen, Henry C., Zhang, Hongkai, Huang, Ailong, Jin, Aishun, Yang, Haitao, Rao, Zihe, Ji, Xiaoyun
Publicado 2022

An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation

por Schoof, Michael, Faust, Bryan, Saunders, Reuben A., Sangwan, Smriti, Rezelj, Veronica, Hoppe, Nick, Boone, Morgane, Billesbølle, Christian B., Puchades, Cristina, Azumaya, Caleigh M., Kratochvil, Huong T., Zimanyi, Marcell, Deshpande, Ishan, Liang, Jiahao, Dickinson, Sasha, Nguyen, Henry C., Chio, Cynthia M., Merz, Gregory E., Thompson, Michael C., Diwanji, Devan, Schaefer, Kaitlin, Anand, Aditya A., Dobzinski, Niv, Zha, Beth Shoshana, Simoneau, Camille R., Leon, Kristoffer, White, Kris M., Chio, Un Seng, Gupta, Meghna, Jin, Mingliang, Li, Fei, Liu, Yanxin, Zhang, Kaihua, Bulkley, David, Sun, Ming, Smith, Amber M., Rizo, Alexandrea N., Moss, Frank, Brilot, Axel F., Pourmal, Sergei, Trenker, Raphael, Pospiech, Thomas, Gupta, Sayan, Barsi-Rhyne, Benjamin, Belyy, Vladislav, Barile-Hill, Andrew W., Nock, Silke, Liu, Yuwei, Krogan, Nevan J., Ralston, Corie Y., Swaney, Danielle L., García-Sastre, Adolfo, Ott, Melanie, Vignuzzi, Marco, Walter, Peter, Manglik, Aashish
Publicado 2020

An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike

por Schoof, Michael, Faust, Bryan, Saunders, Reuben A., Sangwan, Smriti, Rezelj, Veronica, Hoppe, Nick, Boone, Morgane, Billesbølle, Christian B., Puchades, Cristina, Azumaya, Caleigh M., Kratochvil, Huong T., Zimanyi, Marcell, Deshpande, Ishan, Liang, Jiahao, Dickinson, Sasha, Nguyen, Henry C., Chio, Cynthia M., Merz, Gregory E., Thompson, Michael C., Diwanji, Devan, Schaefer, Kaitlin, Anand, Aditya A., Dobzinski, Niv, Zha, Beth Shoshana, Simoneau, Camille R., Leon, Kristoffer, White, Kris M., Chio, Un Seng, Gupta, Meghna, Jin, Mingliang, Li, Fei, Liu, Yanxin, Zhang, Kaihua, Bulkley, David, Sun, Ming, Smith, Amber M., Rizo, Alexandrea N., Moss, Frank, Brilot, Axel F., Pourmal, Sergei, Trenker, Raphael, Pospiech, Thomas, Gupta, Sayan, Barsi-Rhyne, Benjamin, Belyy, Vladislav, Barile-Hill, Andrew W., Nock, Silke, Liu, Yuwei, Krogan, Nevan J., Ralston, Corie Y., Swaney, Danielle L., García-Sastre, Adolfo, Ott, Melanie, Vignuzzi, Marco, Walter, Peter, Manglik, Aashish
Publicado 2020

CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

por Gupta, Meghna, Azumaya, Caleigh M., Moritz, Michelle, Pourmal, Sergei, Diallo, Amy, Merz, Gregory E., Jang, Gwendolyn, Bouhaddou, Mehdi, Fossati, Andrea, Brilot, Axel F., Diwanji, Devan, Hernandez, Evelyn, Herrera, Nadia, Kratochvil, Huong T., Lam, Victor L., Li, Fei, Li, Yang, Nguyen, Henry C., Nowotny, Carlos, Owens, Tristan W., Peters, Jessica K., Rizo, Alexandrea N., Schulze-Gahmen, Ursula, Smith, Amber M., Young, Iris D., Yu, Zanlin, Asarnow, Daniel, Billesbølle, Christian, Campbell, Melody G., Chen, Jen, Chen, Kuei-Ho, Chio, Un Seng, Dickinson, Miles Sasha, Doan, Loan, Jin, Mingliang, Kim, Kate, Li, Junrui, Li, Yen-Li, Linossi, Edmond, Liu, Yanxin, Lo, Megan, Lopez, Jocelyne, Lopez, Kyle E., Mancino, Adamo, Moss, Frank R., Paul, Michael D., Pawar, Komal Ishwar, Pelin, Adrian, Pospiech, Thomas H., Puchades, Cristina, Remesh, Soumya Govinda, Safari, Maliheh, Schaefer, Kaitlin, Sun, Ming, Tabios, Mariano C, Thwin, Aye C., Titus, Erron W., Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Zhang, Kaihua, Zhang, Yang, Zhao, Jianhua, Zhou, Fengbo, Zhou, Yuan, Zuliani-Alvarez, Lorena, Agard, David A, Cheng, Yifan, Fraser, James S, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R., Stroud, Robert M, Swaney, Danielle L, Krogan, Nevan J, Frost, Adam, Rosenberg, Oren S, Verba, Kliment A
Publicado 2021

CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

por Gupta, Meghna, Azumaya, Caleigh M., Moritz, Michelle, Pourmal, Sergei, Diallo, Amy, Merz, Gregory E., Jang, Gwendolyn, Bouhaddou, Mehdi, Fossati, Andrea, Brilot, Axel F., Diwanji, Devan, Hernandez, Evelyn, Herrera, Nadia, Kratochvil, Huong T., Lam, Victor L., Li, Fei, Li, Yang, Nguyen, Henry C., Nowotny, Carlos, Owens, Tristan W., Peters, Jessica K., Rizo, Alexandrea N., Schulze-Gahmen, Ursula, Smith, Amber M., Young, Iris D., Yu, Zanlin, Asarnow, Daniel, Billesbølle, Christian, Campbell, Melody G., Chen, Jen, Chen, Kuei-Ho, Chio, Un Seng, Dickinson, Miles Sasha, Doan, Loan, Jin, Mingliang, Kim, Kate, Li, Junrui, Li, Yen-Li, Linossi, Edmond, Liu, Yanxin, Lo, Megan, Lopez, Jocelyne, Lopez, Kyle E., Mancino, Adamo, Moss, Frank R., Paul, Michael D., Pawar, Komal Ishwar, Pelin, Adrian, Pospiech, Thomas H., Puchades, Cristina, Remesh, Soumya Govinda, Safari, Maliheh, Schaefer, Kaitlin, Sun, Ming, Tabios, Mariano C, Thwin, Aye C., Titus, Erron W., Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Zhang, Kaihua, Zhang, Yang, Zhao, Jianhua, Zhou, Fengbo, Zhou, Yuan, Zuliani-Alvarez, Lorena, Agard, David A, Cheng, Yifan, Fraser, James S, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R., Stroud, Robert M, Swaney, Danielle L, Krogan, Nevan J, Frost, Adam, Rosenberg, Oren S, Verba, Kliment A
Publicado 2021

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

por Gordon, David E., Hiatt, Joseph, Bouhaddou, Mehdi, Rezelj, Veronica V., Ulferts, Svenja, Braberg, Hannes, Jureka, Alexander S., Obernier, Kirsten, Guo, Jeffrey Z., Batra, Jyoti, Kaake, Robyn M., Weckstein, Andrew R., Owens, Tristan W., Gupta, Meghna, Pourmal, Sergei, Titus, Erron W., Cakir, Merve, Soucheray, Margaret, McGregor, Michael, Cakir, Zeynep, Jang, Gwendolyn, O’Meara, Matthew J., Tummino, Tia A., Zhang, Ziyang, Foussard, Helene, Rojc, Ajda, Zhou, Yuan, Kuchenov, Dmitry, Hüttenhain, Ruth, Xu, Jiewei, Eckhardt, Manon, Swaney, Danielle L., Fabius, Jacqueline M., Ummadi, Manisha, Tutuncuoglu, Beril, Rathore, Ujjwal, Modak, Maya, Haas, Paige, Haas, Kelsey M., Naing, Zun Zar Chi, Pulido, Ernst H., Shi, Ying, Barrio-Hernandez, Inigo, Memon, Danish, Petsalaki, Eirini, Dunham, Alistair, Marrero, Miguel Correa, Burke, David, Koh, Cassandra, Vallet, Thomas, Silvas, Jesus A., Azumaya, Caleigh M., Billesbølle, Christian, Brilot, Axel F., Campbell, Melody G., Diallo, Amy, Dickinson, Miles Sasha, Diwanji, Devan, Herrera, Nadia, Hoppe, Nick, Kratochvil, Huong T., Liu, Yanxin, Merz, Gregory E., Moritz, Michelle, Nguyen, Henry C., Nowotny, Carlos, Puchades, Cristina, Rizo, Alexandrea N., Schulze-Gahmen, Ursula, Smith, Amber M., Sun, Ming, Young, Iris D., Zhao, Jianhua, Asarnow, Daniel, Biel, Justin, Bowen, Alisa, Braxton, Julian R., Chen, Jen, Chio, Cynthia M., Chio, Un Seng, Deshpande, Ishan, Doan, Loan, Faust, Bryan, Flores, Sebastian, Jin, Mingliang, Kim, Kate, Lam, Victor L., Li, Fei, Li, Junrui, Li, Yen-Li, Li, Yang, Liu, Xi, Lo, Megan, Lopez, Kyle E., Melo, Arthur A., Moss, Frank R., Nguyen, Phuong, Paulino, Joana, Pawar, Komal Ishwar, Peters, Jessica K., Pospiech, Thomas H., Safari, Maliheh, Sangwan, Smriti, Schaefer, Kaitlin, Thomas, Paul V., Thwin, Aye C., Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Whitis, Natalie, Yu, Zanlin, Zhang, Kaihua, Zhang, Yang, Zhou, Fengbo, Saltzberg, Daniel, Hodder, Anthony J., Shun-Shion, Amber S., Williams, Daniel M., White, Kris M., Rosales, Romel, Kehrer, Thomas, Miorin, Lisa, Moreno, Elena, Patel, Arvind H., Rihn, Suzannah, Khalid, Mir M., Vallejo-Gracia, Albert, Fozouni, Parinaz, Simoneau, Camille R., Roth, Theodore L., Wu, David, Karim, Mohd Anisul, Ghoussaini, Maya, Dunham, Ian, Berardi, Francesco, Weigang, Sebastian, Chazal, Maxime, Park, Jisoo, Logue, James, McGrath, Marisa, Weston, Stuart, Haupt, Robert, Hastie, C. James, Elliott, Matthew, Brown, Fiona, Burness, Kerry A., Reid, Elaine, Dorward, Mark, Johnson, Clare, Wilkinson, Stuart G., Geyer, Anna, Giesel, Daniel M., Baillie, Carla, Raggett, Samantha, Leech, Hannah, Toth, Rachel, Goodman, Nicola, Keough, Kathleen C., Lind, Abigail L., Klesh, Reyna J., Hemphill, Kafi R., Carlson-Stevermer, Jared, Oki, Jennifer, Holden, Kevin, Maures, Travis, Pollard, Katherine S., Sali, Andrej, Agard, David A., Cheng, Yifan, Fraser, James S., Frost, Adam, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R., Stroud, Robert M., Alessi, Dario R., Davies, Paul, Frieman, Matthew B., Ideker, Trey, Abate, Carmen, Jouvenet, Nolwenn, Kochs, Georg, Shoichet, Brian, Ott, Melanie, Palmarini, Massimo, Shokat, Kevan M., García-Sastre, Adolfo, Rassen, Jeremy A., Grosse, Robert, Rosenberg, Oren S., Verba, Kliment A., Basler, Christopher F., Vignuzzi, Marco, Peden, Andrew A., Beltrao, Pedro, Krogan, Nevan J.
Publicado 2020