DICER Inactivation Identifies Pancreatic β-Cell “Disallowed” Genes Targeted by MicroRNAs

por Martinez-Sanchez, Aida, Nguyen-Tu, Marie-Sophie, Rutter, Guy A.
Publicado 2015

Transcription factor-7–like 2 (TCF7L2) gene acts downstream of the Lkb1/Stk11 kinase to control mTOR signaling, β cell growth, and insulin secretion

por Nguyen-Tu, Marie-Sophie, da Silva Xavier, Gabriela, Leclerc, Isabelle, Rutter, Guy A.
Publicado 2018

Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice

por Nguyen-Tu, Marie-Sophie, Martinez-Sanchez, Aida, Leclerc, Isabelle, Rutter, Guy A., da Silva Xavier, Gabriela
Publicado 2020

Inflammation-linked adaptations in dermal microvascular reactivity accompany the development of obesity and type 2 diabetes

por Nguyen-Tu, Marie-Sophie, Nivoit, Pierre, Oréa, Valérie, Lemoine, Sandrine, Acquaviva, Cécile, Pagnon-Minot, Aurélie, Fromy, Bérengère, Sethi, Jaswinder K., Sigaudo-Roussel, Dominique
Publicado 2018

The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca(2+) dynamics in adult mice

por Mitchell, Ryan K., Nguyen-Tu, Marie-Sophie, Chabosseau, Pauline, Callingham, Rebecca M., Pullen, Timothy J., Cheung, Rebecca, Leclerc, Isabelle, Hodson, David J., Rutter, Guy A.
Publicado 2017

Remote control of glucose homeostasis in vivo using photopharmacology

por Mehta, Zenobia B., Johnston, Natalie R., Nguyen-Tu, Marie-Sophie, Broichhagen, Johannes, Schultz, Peter, Larner, Dean P., Leclerc, Isabelle, Trauner, Dirk, Rutter, Guy A., Hodson, David J.
Publicado 2017

Hypothalamic arcuate nucleus glucokinase regulates insulin secretion and glucose homeostasis

por Ma, Yue, Ratnasabapathy, Risheka, Izzi‐Engbeaya, Chioma, Nguyen‐Tu, Marie‐Sophie, Richardson, Errol, Hussain, Sufyan, De Backer, Ivan, Holton, Christopher, Norton, Mariana, Carrat, Gaelle, Schwappach, Blanche, Rutter, Guy A., Dhillo, Waljit S., Gardiner, James
Publicado 2018

In vivo and in vitro characterization of GL0034, a novel long‐acting glucagon‐like peptide‐1 receptor agonist

por Jones, Ben, Burade, Vinod, Akalestou, Elina, Manchanda, Yusman, Ramchunder, Zenouska, Carrat, Gaëlle, Nguyen‐Tu, Marie‐Sophie, Marchetti, Piero, Piemonti, Lorenzo, Leclerc, Isabelle, Thennati, Rajamannar, Vilsboll, Tina, Thorens, Bernard, Tomas, Alejandra, Rutter, Guy A.
Publicado 2022

Glucose in the hypothalamic paraventricular nucleus regulates GLP-1 release

por Ma, Yue, Ratnasabapathy, Risheka, De Backer, Ivan, Izzi-Engbeaya, Chioma, Nguyen-Tu, Marie-Sophie, Cuenco, Joyceline, Jones, Ben, John, Christopher D., Lam, Brian Y.H., Rutter, Guy A., Yeo, Giles S.H., Dhillo, Waljit S., Gardiner, James
Publicado 2020

Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase

por Nguyen-Tu, Marie-Sophie, Harris, Joseph, Martinez-Sanchez, Aida, Chabosseau, Pauline, Hu, Ming, Georgiadou, Eleni, Pollard, Alice, Otero, Pablo, Lopez-Noriega, Livia, Leclerc, Isabelle, Sakamoto, Kei, Schmoll, Dieter, Smith, David M., Carling, David, Rutter, Guy A.
Publicado 2022

MiR-184 expression is regulated by AMPK in pancreatic islets

por Martinez-Sanchez, Aida, Nguyen-Tu, Marie-Sophie, Cebola, Ines, Yavari, Arash, Marchetti, Piero, Piemonti, Lorenzo, de Koning, Eelco, Shapiro, A. M. James, Johnson, Paul, Sakamoto, Kei, Smith, David M., Leclerc, Isabelle, Ashrafian, Houman, Ferrer, Jorge, Rutter, Guy A.
Publicado 2018

LKB1 and AMPK differentially regulate pancreatic β-cell identity

por Kone, Marina, Pullen, Timothy J., Sun, Gao, Ibberson, Mark, Martinez-Sanchez, Aida, Sayers, Sophie, Nguyen-Tu, Marie-Sophie, Kantor, Chase, Swisa, Avital, Dor, Yuval, Gorman, Tracy, Ferrer, Jorge, Thorens, Bernard, Reimann, Frank, Gribble, Fiona, McGinty, James A., Chen, Lingling, French, Paul M., Birzele, Fabian, Hildebrandt, Tobias, Uphues, Ingo, Rutter, Guy A.
Publicado 2014

Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice

por Carrat, Gaelle R., Hu, Ming, Nguyen-Tu, Marie-Sophie, Chabosseau, Pauline, Gaulton, Kyle J., van de Bunt, Martijn, Siddiq, Afshan, Falchi, Mario, Thurner, Matthias, Canouil, Mickaël, Pattou, Francois, Leclerc, Isabelle, Pullen, Timothy J., Cane, Matthew C., Prabhala, Priyanka, Greenwald, William, Schulte, Anke, Marchetti, Piero, Ibberson, Mark, MacDonald, Patrick E., Manning Fox, Jocelyn E., Gloyn, Anna L., Froguel, Philippe, Solimena, Michele, McCarthy, Mark I., Rutter, Guy A.
Publicado 2017

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function

por Yavari, Arash, Stocker, Claire J., Ghaffari, Sahar, Wargent, Edward T., Steeples, Violetta, Czibik, Gabor, Pinter, Katalin, Bellahcene, Mohamed, Woods, Angela, Martínez de Morentin, Pablo B., Cansell, Céline, Lam, Brian Y.H., Chuster, André, Petkevicius, Kasparas, Nguyen-Tu, Marie-Sophie, Martinez-Sanchez, Aida, Pullen, Timothy J., Oliver, Peter L., Stockenhuber, Alexander, Nguyen, Chinh, Lazdam, Merzaka, O’Dowd, Jacqueline F., Harikumar, Parvathy, Tóth, Mónika, Beall, Craig, Kyriakou, Theodosios, Parnis, Julia, Sarma, Dhruv, Katritsis, George, Wortmann, Diana D.J., Harper, Andrew R., Brown, Laurence A., Willows, Robin, Gandra, Silvia, Poncio, Victor, de Oliveira Figueiredo, Márcio J., Qi, Nathan R., Peirson, Stuart N., McCrimmon, Rory J., Gereben, Balázs, Tretter, László, Fekete, Csaba, Redwood, Charles, Yeo, Giles S.H., Heisler, Lora K., Rutter, Guy A., Smith, Mark A., Withers, Dominic J., Carling, David, Sternick, Eduardo B., Arch, Jonathan R.S., Cawthorne, Michael A., Watkins, Hugh, Ashrafian, Houman
Publicado 2016