GIANI – open-source software for automated analysis of 3D microscopy images

por Barry, David J., Gerri, Claudia, Bell, Donald M., D'Antuono, Rocco, Niakan, Kathy K.
Publicado 2022

Pairing of Homologous Regions in the Mouse Genome Is Associated with Transcription but Not Imprinting Status

por Krueger, Christel, King, Michelle R., Krueger, Felix, Branco, Miguel R., Osborne, Cameron S., Niakan, Kathy K., Higgins, Michael J., Reik, Wolf
Publicado 2012

Activation of the Aryl Hydrocarbon Receptor Interferes with Early Embryonic Development

por Gialitakis, Manolis, Tolaini, Mauro, Li, Ying, Pardo, Mercedes, Yu, Lu, Toribio, Ana, Choudhary, Jyoti S., Niakan, Kathy, Papayannopoulos, Venizelos, Stockinger, Brigitta
Publicado 2017

MICA: a multi-omics method to predict gene regulatory networks in early human embryos

por Alanis-Lobato, Gregorio, Bartlett, Thomas E, Huang, Qiulin, Simon, Claire S, McCarthy, Afshan, Elder, Kay, Snell, Phil, Christie, Leila, Niakan, Kathy K
Publicado 2023

Human embryo research, stem cell-derived embryo models and in vitro gametogenesis: Considerations leading to the revised ISSCR guidelines

por Clark, Amander T., Brivanlou, Ali, Fu, Jianping, Kato, Kazuto, Mathews, Debra, Niakan, Kathy K., Rivron, Nicolas, Saitou, Mitinori, Surani, Azim, Tang, Fuchou, Rossant, Janet
Publicado 2021

KLF17 promotes human naïve pluripotency but is not required for its establishment

por Lea, Rebecca A., McCarthy, Afshan, Boeing, Stefan, Fallesen, Todd, Elder, Kay, Snell, Phil, Christie, Leila, Adkins, Sarah, Shaikly, Valerie, Taranissi, Mohamed, Niakan, Kathy K.
Publicado 2021

Gata6 potently initiates reprograming of pluripotent and differentiated cells to extraembryonic endoderm stem cells

por Wamaitha, Sissy E., del Valle, Ignacio, Cho, Lily T.Y., Wei, Yingying, Fogarty, Norah M.E., Blakeley, Paul, Sherwood, Richard I., Ji, Hongkai, Niakan, Kathy K.
Publicado 2015

Defining the three cell lineages of the human blastocyst by single-cell RNA-seq

por Blakeley, Paul, Fogarty, Norah M. E., del Valle, Ignacio, Wamaitha, Sissy E., Hu, Tim Xiaoming, Elder, Kay, Snell, Philip, Christie, Leila, Robson, Paul, Niakan, Kathy K.
Publicado 2015

The BCL-2 pathway preserves mammalian genome integrity by eliminating recombination-defective oocytes

por ElInati, Elias, Zielinska, Agata P., McCarthy, Afshan, Kubikova, Nada, Maciulyte, Valdone, Mahadevaiah, Shantha, Sangrithi, Mahesh N., Ojarikre, Obah, Wells, Dagan, Niakan, Kathy K., Schuh, Melina, Turner, James M. A.
Publicado 2020

BRACHYURY and CDX2 Mediate BMP-Induced Differentiation of Human and Mouse Pluripotent Stem Cells into Embryonic and Extraembryonic Lineages

por Bernardo, Andreia S., Faial, Tiago, Gardner, Lucy, Niakan, Kathy K., Ortmann, Daniel, Senner, Claire E., Callery, Elizabeth M., Trotter, Matthew W., Hemberger, Myriam, Smith, James C., Bardwell, Lee, Moffett, Ashley, Pedersen, Roger A.
Publicado 2011

SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice

por Hirota, Takayuki, Blakeley, Paul, Sangrithi, Mahesh N., Mahadevaiah, Shantha K., Encheva, Vesela, Snijders, Ambrosius P., ElInati, Elias, Ojarikre, Obah A., de Rooij, Dirk G., Niakan, Kathy K., Turner, James M.A.
Publicado 2018

Self-organisation of the human embryo in the absence of maternal tissues

por Shahbazi, Marta N., Jedrusik, Agnieszka, Vuoristo, Sanna, Recher, Gaelle, Hupalowska, Anna, Bolton, Virginia, Fogarty, Norah N. M., Campbell, Alison, Devito, Liani, Ilic, Dusko, Khalaf, Yakoub, Niakan, Kathy K., Fishel, Simon, Zernicka-Goetz, Magdalena
Publicado 2016

TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells

por Osnato, Anna, Brown, Stephanie, Krueger, Christel, Andrews, Simon, Collier, Amanda J, Nakanoh, Shota, Quiroga Londoño, Mariana, Wesley, Brandon T, Muraro, Daniele, Brumm, A Sophie, Niakan, Kathy K, Vallier, Ludovic, Ortmann, Daniel, Rugg-Gunn, Peter J
Publicado 2021

Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation

por Tomaz, Rute A., Harman, Jennifer L., Karimlou, Donja, Weavers, Lauren, Fritsch, Lauriane, Bou-Kheir, Tony, Bell, Emma, del Valle Torres, Ignacio, Niakan, Kathy K., Fisher, Cynthia, Joshi, Onkar, Stunnenberg, Hendrik G., Curry, Edward, Ait-Si-Ali, Slimane, Jørgensen, Helle F., Azuara, Véronique
Publicado 2017

IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche

por Wamaitha, Sissy E., Grybel, Katarzyna J., Alanis-Lobato, Gregorio, Gerri, Claudia, Ogushi, Sugako, McCarthy, Afshan, Mahadevaiah, Shantha K., Healy, Lyn, Lea, Rebecca A., Molina-Arcas, Miriam, Devito, Liani G., Elder, Kay, Snell, Phil, Christie, Leila, Downward, Julian, Turner, James M. A., Niakan, Kathy K.
Publicado 2020

Genome editing reveals a role for OCT4 in human embryogenesis

por Fogarty, Norah M. E., McCarthy, Afshan, Snijders, Kirsten E., Powell, Benjamin E., Kubikova, Nada, Blakeley, Paul, Lea, Rebecca, Elder, Kay, Wamaitha, Sissy E., Kim, Daesik, Maciulyte, Valdone, Kleinjung, Jens, Kim, Jin-Soo, Wells, Dagan, Vallier, Ludovic, Bertero, Alessandro, Turner, James M. A., Niakan, Kathy K.
Publicado 2017

Effects of thyroid hormone on mitochondria and metabolism of human preimplantation embryos

por Noli, Laila, Khorsandi, Shirin E., Pyle, Angela, Giritharan, Gnanaratnam, Fogarty, Norah, Capalbo, Antonio, Devito, Liani, Jovanovic, Vladimir M., Khurana, Preeti, Rosa, Hannah, Kolundzic, Nikola, Cvoro, Aleksandra, Niakan, Kathy K., Malik, Afshan, Foulk, Russell, Heaton, Nigel, Ardawi, Mohammad Saleh, Chinnery, Patrick F., Ogilvie, Caroline, Khalaf, Yacoub, Ilic, Dusko
Publicado 2019

Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease

por Hyslop, Louise A., Blakeley, Paul, Craven, Lyndsey, Richardson, Jessica, Fogarty, Norah M.E., Fragouli, Elpida, Lamb, Mahdi, Wamaitha, Sissy E., Prathalingam, Nilendran, Zhang, Qi, O’Keefe, Hannah, Takeda, Yuko, Arizzi, Lucia, Alfarawati, Samer, Tuppen, Helen A., Irving, Laura, Kalleas, Dimitrios, Choudhary, Meenakshi, Wells, Dagan, Murdoch, Alison P, Turnbull, Douglass M., Niakan, Kathy K., Herbert, Mary
Publicado 2016

ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update

por Lovell-Badge, Robin, Anthony, Eric, Barker, Roger A., Bubela, Tania, Brivanlou, Ali H., Carpenter, Melissa, Charo, R. Alta, Clark, Amander, Clayton, Ellen, Cong, Yali, Daley, George Q., Fu, Jianping, Fujita, Misao, Greenfield, Andy, Goldman, Steve A., Hill, Lori, Hyun, Insoo, Isasi, Rosario, Kahn, Jeffrey, Kato, Kazuto, Kim, Jin-Soo, Kimmelman, Jonathan, Knoblich, Jürgen A., Mathews, Debra, Montserrat, Nuria, Mosher, Jack, Munsie, Megan, Nakauchi, Hiromitsu, Naldini, Luigi, Naughton, Gail, Niakan, Kathy, Ogbogu, Ubaka, Pedersen, Roger, Rivron, Nicolas, Rooke, Heather, Rossant, Janet, Round, Jeff, Saitou, Mitinori, Sipp, Douglas, Steffann, Julie, Sugarman, Jeremy, Surani, Azim, Takahashi, Jun, Tang, Fuchou, Turner, Leigh, Zettler, Patricia J., Zhai, Xiaomei
Publicado 2021