The apoptotic response in HCT116(BAX-/- )cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein

por Semaan, Sheila J, Nickells, Robert W
Publicado 2010

A single nucleotide polymorphism in the Bax gene promoter affects transcription and influences retinal ganglion cell death

por Semaan, Sheila J, Li, Yan, Nickells, Robert W
Publicado 2010

Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis

por Pelzel, Heather R, Schlamp, Cassandra L, Nickells, Robert W
Publicado 2010

Accelerated retinal ganglion cell death in mice deficient in the Sigma-1 receptor

por Mavlyutov, Timur A., Nickells, Robert W., Guo, Lian-Wang
Publicado 2011

Live-cell imaging to measure BAX recruitment kinetics to mitochondria during apoptosis

por Maes, Margaret E., Schlamp, Cassandra L., Nickells, Robert W.
Publicado 2017

Meta-analysis of transcriptomic changes in optic nerve injury and neurodegenerative models reveals a fundamental response to injury throughout the central nervous system.

por Donahue, Ryan J., Moller-Trane, Ralph, Nickells, Robert W.
Publicado 2017

Dominant inheritance of retinal ganglion cell resistance to optic nerve crush in mice

por Li, Yan, Semaan, Sheila J, Schlamp, Cassandra L, Nickells, Robert W
Publicado 2007

The effect of glial fibrillary acidic protein expression on neurite outgrowth from retinal explants in a permissive environment

por Toops, Kimberly A, Hagemann, Tracy L, Messing, Albee, Nickells, Robert W
Publicado 2012

Histone deacetylase 3 (HDAC3) plays an important role in retinal ganglion cell death after acute optic nerve injury

por Schmitt, Heather M, Pelzel, Heather R, Schlamp, Cassandra L, Nickells, Robert W
Publicado 2014

AAV2-Mediated Transduction of the Mouse Retina After Optic Nerve Injury

por Nickells, Robert W., Schmitt, Heather M., Maes, Margaret E., Schlamp, Cassandra L.
Publicado 2017

BCLX(L) gene therapy moderates neuropathology in the DBA/2J mouse model of inherited glaucoma

por Donahue, Ryan J., Fehrman, Rachel L., Gustafson, Jenna R., Nickells, Robert W.
Publicado 2021

Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric

por Schlamp, Cassandra L, Li, Yan, Dietz, Joel A, Janssen, Katherine T, Nickells, Robert W
Publicado 2006

The effects of a mitochondrial targeted peptide (elamipretide/SS31) on BAX recruitment and activation during apoptosis

por Grosser, Joshua A., Fehrman, Rachel L., Keefe, Dennis, Redmon, Martin, Nickells, Robert W.
Publicado 2021

Tumor necrosis factor alpha has an early protective effect on retinal ganglion cells after optic nerve crush

por Mac Nair, Caitlin E, Fernandes, Kimberly A, Schlamp, Cassandra L, Libby, Richard T, Nickells, Robert W
Publicado 2014

BclX(L) (Bcl2l1) gene therapy lessens retinal ganglion cell soma loss but not axonal degeneration after acute axonal injury

por Marola, Olivia J., Yablonski, Sarah E. R., Shrager, Peter G., Nickells, Robert W., Libby, Richard T.
Publicado 2022

BAX activation in mouse retinal ganglion cells occurs in two temporally and mechanistically distinct steps

por Maes, Margaret E., Donahue, Ryan J., Schlamp, Cassandra L., Marola, Olivia J., Libby, Richard T., Nickells, Robert
Publicado 2023

Contralateral Astrocyte Response to Acute Optic Nerve Damage Is Mitigated by PANX1 Channel Activity

por Wurl, Jasmine A., Mac Nair, Caitlin E., Dietz, Joel A., Shestopalov, Valery I., Nickells, Robert W.
Publicado 2023

Rgcs1, a dominant QTL that affects retinal ganglion cell death after optic nerve crush in mice

por Dietz, Joel A, Li, Yan, Chung, Lisa M, Yandell, Brian S, Schlamp, Cassandra L, Nickells, Robert W
Publicado 2008

Retinal glial responses to optic nerve crush are attenuated in Bax-deficient mice and modulated by purinergic signaling pathways

por Mac Nair, Caitlin E., Schlamp, Cassandra L., Montgomery, Angela D., Shestopalov, Valery I., Nickells, Robert W.
Publicado 2016

The Influence of Mitochondrial Dynamics and Function on Retinal Ganglion Cell Susceptibility in Optic Nerve Disease

por Muench, Nicole A., Patel, Sonia, Maes, Margaret E., Donahue, Ryan J., Ikeda, Akihiro, Nickells, Robert W.
Publicado 2021