Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression

por Zagare, Alise, Barmpa, Kyriaki, Smajic, Semra, Smits, Lisa M., Grzyb, Kamil, Grünewald, Anne, Skupin, Alexander, Nickels, Sarah L., Schwamborn, Jens C.
Publicado 2022

Omics data integration suggests a potential idiopathic Parkinson’s disease signature

por Zagare, Alise, Preciat, German, Nickels, Sarah. L., Luo, Xi, Monzel, Anna S., Gomez-Giro, Gemma, Robertson, Graham, Jaeger, Christian, Sharif, Jafar, Koseki, Haruhiko, Diederich, Nico J., Glaab, Enrico, Fleming, Ronan M. T., Schwamborn, Jens C.
Publicado 2023

Treating Parkinson’s Disease with Human Bone Marrow Mesenchymal Stem Cell Secretome: A Translational Investigation Using Human Brain Organoids and Different Routes of In Vivo Admin...

por Mendes-Pinheiro, Bárbara, Campos, Jonas, Marote, Ana, Soares-Cunha, Carina, Nickels, Sarah L., Monzel, Anna S., Cibrão, Jorge R., Loureiro-Campos, Eduardo, Serra, Sofia C., Barata-Antunes, Sandra, Duarte-Silva, Sara, Pinto, Luísa, Schwamborn, Jens C., Salgado, António J.
Publicado 2023

3D Cultures of Parkinson's Disease‐Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing

por Bolognin, Silvia, Fossépré, Marie, Qing, Xiaobing, Jarazo, Javier, Ščančar, Janez, Moreno, Edinson Lucumi, Nickels, Sarah L., Wasner, Kobi, Ouzren, Nassima, Walter, Jonas, Grünewald, Anne, Glaab, Enrico, Salamanca, Luis, Fleming, Ronan M. T., Antony, Paul M. A., Schwamborn, Jens C.
Publicado 2018

Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality

por Walter, Jonas, Bolognin, Silvia, Antony, Paul M.A., Nickels, Sarah L., Poovathingal, Suresh K., Salamanca, Luis, Magni, Stefano, Perfeito, Rita, Hoel, Fredrik, Qing, Xiaobing, Jarazo, Javier, Arias-Fuenzalida, Jonathan, Ignac, Tomasz, Monzel, Anna S., Gonzalez-Cano, Laura, Pereira de Almeida, Luis, Skupin, Alexander, Tronstad, Karl J., Schwamborn, Jens C.
Publicado 2019