The role of extracellular histones in COVID‐19

por de Vries, Femke, Huckriede, Joram, Wichapong, Kanin, Reutelingsperger, Chris, Nicolaes, Gerry A. F.
Publicado 2022

Screening Outside the Catalytic Site: Inhibition of Macromolecular Inter-actions Through Structure-Based Virtual Ligand Screening Experiments

por Sperandio, Olivier, Miteva, Maria A, Segers, Kenneth, Nicolaes, Gerry A. F, Villoutreix, Bruno O
Publicado 2008

Understanding the functional difference between growth arrest-specific protein 6 and protein S: an evolutionary approach

por Studer, Romain A., Opperdoes, Fred R., Nicolaes, Gerry A. F., Mulder, André B., Mulder, René
Publicado 2014

Structure-based peptide design targeting intrinsically disordered proteins: Novel histone H4 and H2A peptidic inhibitors

por Wichapong, Kanin, Silvestre-Roig, Carlos, Braster, Quinte, Schumski, Ariane, Soehnlein, Oliver, Nicolaes, Gerry A.F.
Publicado 2021

PAD4 takes charge during neutrophil activation: Impact of PAD4 mediated NET formation on immune‐mediated disease

por Liu, Xiaosong, Arfman, Tom, Wichapong, Kanin, Reutelingsperger, Chris P. M., Voorberg, Jan, Nicolaes, Gerry A. F.
Publicado 2021

Role of Vitamin K-Dependent Factors Protein S and GAS6 and TAM Receptors in SARS-CoV-2 Infection and COVID-19-Associated Immunothrombosis

por Tutusaus, Anna, Marí, Montserrat, Ortiz-Pérez, José T., Nicolaes, Gerry A. F., Morales, Albert, García de Frutos, Pablo
Publicado 2020

ptFVa (Pseudonaja Textilis Venom-Derived Factor Va) Retains Structural Integrity Following Proteolysis by Activated Protein C

por Schreuder, Mark, Liu, Xiaosong, Cheung, Ka Lei, Reitsma, Pieter H., Nicolaes, Gerry A.F., Bos, Mettine H.A.
Publicado 2021

Acetaminophen Overdose as a Potential Risk Factor for Parkinson's Disease

por Bohler, Sacha, Liu, Xiaosong, Krauskopf, Julian, Caiment, Florian, Aubrecht, Jiri, Nicolaes, Gerry A. F., Kleinjans, Jos C. S., Briedé, Jacco J.
Publicado 2019

Conformational plasticity of ADAMTS13 in hemostasis and autoimmunity

por Ercig, Bogac, Arfman, Tom, Hrdinova, Johana, Wichapong, Kanin, Reutelingsperger, Chris P.M., Vanhoorelbeke, Karen, Nicolaes, Gerry A.F., Voorberg, Jan
Publicado 2021

Effects of Exogenous Recombinant APC in Mouse Models of Ischemia Reperfusion Injury and of Atherosclerosis

por Wildhagen, Karin C. A. A., Schrijver, Roy, Beckers, Linda, ten Cate, Hugo, Reutelingsperger, Chris P. M., Lutgens, Esther, Nicolaes, Gerry A. F.
Publicado 2014

Histone H3 Cleavage in Severe COVID-19 ICU Patients

por Huckriede, Joram, de Vries, Femke, Hultström, Michael, Wichapong, Kanin, Reutelingsperger, Chris, Lipcsey, Miklos, Garcia de Frutos, Pablo, Frithiof, Robert, Nicolaes, Gerry A. F.
Publicado 2021

iPPI-DB: an online database of modulators of protein–protein interactions

por Labbé, Céline M., Kuenemann, Mélaine A., Zarzycka, Barbara, Vriend, Gert, Nicolaes, Gerry A.F., Lagorce, David, Miteva, Maria A., Villoutreix, Bruno O., Sperandio, Olivier
Publicado 2016

Inhibition of Neutral Sphingomyelinase 2 by Novel Small Molecule Inhibitors Results in Decreased Release of Extracellular Vesicles by Vascular Smooth Muscle Cells and Attenuated Ca...

por Pavlic, Angelina, Poelman, Hessel, Wasilewski, Grzegorz, Wichapong, Kanin, Lux, Petra, Maassen, Cecile, Lutgens, Esther, Schurgers, Leon J., Reutelingsperger, Chris P., Nicolaes, Gerry A. F.
Publicado 2023

Modifying ADAMTS13 to modulate binding of pathogenic autoantibodies of patients with acquired thrombotic thrombocytopenic purpura

por Graça, Nuno A. G., Ercig, Bogac, Pereira, Leydi Carolina Velásquez, Kangro, Kadri, Kaijen, Paul, Nicolaes, Gerry A. F., Veyradier, Agnès, Coppo, Paul, Vanhoorelbeke, Karen, Männik, Andres, Voorberg, Jan
Publicado 2019

Growth Arrest-Specific Factor 6 (GAS6) Is Increased in COVID-19 Patients and Predicts Clinical Outcome

por Morales, Albert, Rojo Rello, Silvia, Cristóbal, Helena, Fiz-López, Aida, Arribas, Elisa, Marí, Montserrat, Tutusaus, Anna, de la Cal-Sabater, Paloma, Nicolaes, Gerry A.F., Ortiz-Pérez, José T., Bernardo, David, García de Frutos, Pablo
Publicado 2021

Structure‐function of anticoagulant TIX‐5, the inhibitor of factor Xa‐mediated FV activation

por Maag, Anja, Sharma, Priyanka, Schuijt, Tim J., Kopatz, Wil F., Kruijswijk, Daniëlle, Marquart, J. Arnoud, van der Poll, Tom, Hackeng, Tilman M., Nicolaes, Gerry A. F., Meijers, Joost C. M., Bos, Mettine H. A., van ’t Veer, Cornelis
Publicado 2021

Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear

por Hrdinova, Johana, Fernández, Delia I., Ercig, Bogac, Tullemans, Bibian M. E., Suylen, Dennis P. L., Agten, Stijn M., Jurk, Kerstin, Hackeng, Tilman M., Vanhoorelbeke, Karen, Voorberg, Jan, Reutelingsperger, Chris P. M., Wichapong, Kanin, Heemskerk, Johan W. M., Nicolaes, Gerry A. F.
Publicado 2022

Impaired Antibody Response Is Associated with Histone-Release, Organ Dysfunction and Mortality in Critically Ill COVID-19 Patients

por Lagedal, Rickard, Eriksson, Oskar, Sörman, Anna, Huckriede, Joram B., Kristensen, Bjarne, Franzén, Stephanie, Larsson, Anders, Bergqvist, Anders, Alving, Kjell, Forslund, Anders, Persson, Barbro, Ekdahl, Kristina N., Garcia de Frutos, Pablo, Nilsson, Bo, Nicolaes, Gerry A. F., Lipcsey, Miklos, Hultström, Michael, Frithiof, Robert
Publicado 2022

Evolution of NETosis markers and DAMPs have prognostic value in critically ill COVID-19 patients

por Huckriede, Joram, Anderberg, Sara Bülow, Morales, Albert, de Vries, Femke, Hultström, Michael, Bergqvist, Anders, Ortiz-Pérez, José T., Sels, Jan Willem, Wichapong, Kanin, Lipcsey, Miklos, van de Poll, Marcel, Larsson, Anders, Luther, Tomas, Reutelingsperger, Chris, de Frutos, Pablo Garcia, Frithiof, Robert, Nicolaes, Gerry A. F.
Publicado 2021

Extracellular histone release by renal cells after warm and cold ischemic kidney injury: Studies in an ex-vivo porcine kidney perfusion model

por van Smaalen, Tim C., Beurskens, Danielle M. H., Kox, Jasper J. H. F. M., Polonia, Rasheendra, Vos, Rein, Duimel, Hans, van de Wetering, Willine J., López-Iglesias, Carmen, Reutelingsperger, Chris P., Ernest van Heurn, L. W., Peutz-Kootstra, Carine J., Nicolaes, Gerry A. F.
Publicado 2023