Shear-Dependent Platelet Aggregation: Mechanisms and Therapeutic Opportunities

por Rana, Akshita, Westein, Erik, Niego, Be'eri, Hagemeyer, Christoph E.
Publicado 2019

A novel ex vivo approach for measuring plasminogen activation upon established plasma clots

por Palazzolo, Jason S., Medcalf, Robert L., Hagemeyer, Christoph E., Niego, Be'eri
Publicado 2022

Assessment of the epi-pericardial fibrotic substrate by collagen-targeted probes

por Ezeani, Martin, Noor, Asif, Donnelly, Paul S., Niego, Be’eri, Hagemeyer, Christoph E.
Publicado 2022

LDL receptor blockade reduces mortality in a mouse model of ischaemic stroke without improving tissue-type plasminogen activator-induced brain haemorrhage: towards pre-clinical sim...

por Niego, Be’eri, Broughton, Brad R. S., Ho, Heidi, Sobey, Christopher G., Medcalf, Robert L.
Publicado 2017

t-PA Suppresses the Immune Response and Aggravates Neurological Deficit in a Murine Model of Ischemic Stroke

por Draxler, Dominik F., Lee, Felix, Ho, Heidi, Keragala, Charithani B., Medcalf, Robert L., Niego, Be'eri
Publicado 2019

Collagen‐Targeted Peptides for Molecular Imaging of Diffuse Cardiac Fibrosis

por Ezeani, Martin, Noor, Asif, Alt, Karen, Lal, Sean, Donnelly, Paul S., Hagemeyer, Christoph E., Niego, Be’eri
Publicado 2021

Tissue-Type Plasminogen Activator and Tenecteplase-Mediated Increase in Blood Brain Barrier Permeability Involves Cell Intrinsic Complement

por Keragala, Charithani B., Woodruff, Trent M., Liu, Zikou, Niego, Be'eri, Ho, Heidi, McQuilten, Zoe, Medcalf, Robert L.
Publicado 2020

Selective inhibition of brain endothelial Rho-kinase-2 provides optimal protection of an in vitro blood-brain barrier from tissue-type plasminogen activator and plasmin

por Niego, Be’eri, Lee, Natasha, Larsson, Pia, De Silva, T. Michael, Au, Amanda E-Ling, McCutcheon, Fiona, Medcalf, Robert L.
Publicado 2017

Platelet-targeted thrombolysis for treatment of acute ischemic stroke

por Palazzolo, Jason S., Ale, Anukreity, Ho, Heidi, Jagdale, Shweta, Broughton, Brad R. S., Medcalf, Robert L., Wright, David K., Alt, Karen, Hagemeyer, Christoph E., Niego, Be’eri
Publicado 2022

Novel Thrombolytic Drug Based on Thrombin Cleavable Microplasminogen Coupled to a Single‐Chain Antibody Specific for Activated GPIIb/IIIa

por Bonnard, Thomas, Tennant, Zachary, Niego, Be'Eri, Kanojia, Ruchi, Alt, Karen, Jagdale, Shweta, Law, Lok Soon, Rigby, Sheena, Medcalf, Robert Lindsay, Peter, Karlheinz, Hagemeyer, Christoph Eugen
Publicado 2017

The Influence of Differentially Expressed Tissue-Type Plasminogen Activator in Experimental Autoimmune Encephalomyelitis: Implications for Multiple Sclerosis

por Dahl, Lisa CM, Nasa, Zeyad, Chung, JieYu, Niego, Be’eri, Tarlac, Volga, Ho, Heidi, Galle, Adam, Petratos, Steven, Lee, Jae Young, Alderuccio, Frank, Medcalf, Robert L.
Publicado 2016

Targeting shear gradient activated von Willebrand factor by the novel single-chain antibody A1 reduces occlusive thrombus formation in vitro

por Hoefer, Thomas, Rana, Akshita, Niego, Be’eri, Jagdale, Shweta, Albers, Hugo J., Gardiner, Elizabeth E., Andrews, Robert K., van der Meer, Andries D., Hagemeyer, Christoph E., Westein, Erik
Publicado 2020

Plasmin Generation Potential and Recanalization in Acute Ischaemic Stroke; an Observational Cohort Study of Stroke Biobank Samples

por Lillicrap, Thomas, Keragala, Charithani B., Draxler, Dominik F., Chan, Jilly, Ho, Heidi, Harman, Stevi, Niego, Be'eri, Holliday, Elizabeth, Levi, Christopher R., Garcia-Esperon, Carlos, Spratt, Neil, Gyawali, Prajwal, Bivard, Andrew, Parsons, Mark W., Montaner, Joan, Bustamante, Alejandro, Cadenas, Israel Fernandez, Cloud, Geoffrey, Maguire, Jane M., Lincz, Lisa, Kleinig, Timothy, Attia, John, Koblar, Simon, Hamilton-Bruce, Monica Anne, Choi, Philip, Worrall, Bradford B., Medcalf, Robert L.
Publicado 2020