Pharmacokinetics and modeling of immune cell trafficking: quantifying differential influences of target tissues versus lymphocytes in SJL and lipopolysaccharide-treated mice

por Banks, William A, Niehoff, Michael L, Ponzio, Nicholas M, Erickson, Michelle A, Zalcman, Steven S
Publicado 2012

Protective Effect of Topiramate on Hyperglycemia-Induced Cerebral Oxidative Stress, Pericyte Loss and Learning Behavior in Diabetic Mice

por Price, Tulin O., Farr, Susan A., Niehoff, Michael L., Ercal, Nuran, Morley, John E., Shah, Gul N.
Publicado 2015

Serum progranulin levels are associated with frailty in middle-aged individuals

por Nguyen, Andrew D., Malmstrom, Theodore K., Niehoff, Michael L., Aziz, Asef, Miller, Douglas K., Morley, John E.
Publicado 2020

Adenosine A(3) receptor as a novel therapeutic target to reduce secondary events and improve neurocognitive functions following traumatic brain injury

por Farr, Susan A., Cuzzocrea, Salvatore, Esposito, Emanuela, Campolo, Michela, Niehoff, Michael L., Doyle, Timothy M., Salvemini, Daniela
Publicado 2020

Biochemical, biomarker, and behavioral characterization of the Grn(R493X) mouse model of frontotemporal dementia

por Smith, Denise M., Aggarwal, Geetika, Niehoff, Michael L., Jones, Spencer A., Banerjee, Subhashis, Farr, Susan A., Nguyen, Andrew D.
Publicado 2023

Targeting nonsense-mediated RNA decay does not increase progranulin levels in the Grn (R493X) mouse model of frontotemporal dementia

por Smith, Denise M., Niehoff, Michael L., Ling, Karen, Jafar-Nejad, Paymaan, Rigo, Frank, Farr, Susan A., Wilkinson, Miles F., Nguyen, Andrew D.
Publicado 2023

Sphingosine-1-phosphate receptor 1 activation in the central nervous system drives cisplatin-induced cognitive impairment

por Squillace, Silvia, Niehoff, Michael L., Doyle, Timothy M., Green, Michael, Esposito, Emanuela, Cuzzocrea, Salvatore, Arnatt, Christopher K., Spiegel, Sarah, Farr, Susan A., Salvemini, Daniela
Publicado 2022

The GLP-1 Receptor Agonist Liraglutide Improves Memory Function and Increases Hippocampal CA1 Neuronal Numbers in a Senescence-Accelerated Mouse Model of Alzheimer’s Disease

por Hansen, Henrik H., Fabricius, Katrine, Barkholt, Pernille, Niehoff, Michael L., Morley, John E., Jelsing, Jacob, Pyke, Charles, Knudsen, Lotte Bjerre, Farr, Susan A., Vrang, Niels
Publicado 2015

Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer’s disease

por Roby, Deborah A., Ruiz, Fernanda, Kermath, Bailey A., Voorhees, Jaymie R., Niehoff, Michael, Zhang, Jinsong, Morley, John E., Musiek, Erik S., Farr, Susan A., Burris, Thomas P.
Publicado 2019

Adropin correlates with aging-related neuropathology in humans and improves cognitive function in aging mice

por Banerjee, Subhashis, Ghoshal, Sarbani, Girardet, Clemence, DeMars, Kelly M., Yang, Changjun, Niehoff, Michael L., Nguyen, Andrew D., Jayanth, Prerana, Hoelscher, Brittany A., Xu, Fenglian, Banks, William A., Hansen, Kim M., Zhang, Jinsong, Candelario-Jalil, Eduardo, Farr, Susan A., Butler, Andrew A.
Publicado 2021

A DUAL MTOR/NAD+ ACTING GEROTHERAPY

por Li, Jinmei, Kumar, Sandeep, Miachin, Kirill, Bean, Nicholas L., Halawi, Ornella, Lee, Scott, Park, JiWoong, Pierre, Tanya H., Hor, Jin-Hui, Ng, Shi-Yan, Wallace, Kelvin J., Rindtorff, Niklas, Miller, Timothy M., Niehoff, Michael L., Farr, Susan A., Kletzien, Rolf F., Colca, Jerry, Tanis, Steven P., Chen, Yana, Griffett, Kristine, McCommis, Kyle S., Finck, Brian N., Peterson, Tim R.
Publicado 2023