Multigene Panel Testing Yields High Rates of Clinically Actionable Variants Among Patients With Colorectal Cancer

por Coughlin, Sarah E., Heald, Brandie, Clark, Dana Farengo, Nielsen, Sarah M., Hatchell, Kathryn E., Esplin, Edward D., Katona, Bryson W.
Publicado 2022

Underdiagnosis of Hereditary Colorectal Cancers Among Medicare Patients: Genetic Testing Criteria for Lynch Syndrome Miss the Mark

por Muller, Charles, Nielsen, Sarah M., Hatchell, Kathryn E., Yang, Shan, Michalski, Scott T., Hamlington, Barbara, Nussbaum, Robert L., Esplin, Edward D., Kupfer, Sonia S.
Publicado 2021

Ashkenazi Jewish and Other White APC I1307K Carriers Are at Higher Risk for Multiple Cancers

por Forkosh, Esther, Bergel, Michael, Hatchell, Kathryn E., Nielsen, Sarah M., Heald, Brandie, Benson, Ariel A., Friedman, Eitan, Esplin, Edward D., Katz, Lior H.
Publicado 2022

Yield and Utility of Germline Testing Following Tumor Sequencing in Patients With Cancer

por Lincoln, Stephen E., Nussbaum, Robert L., Kurian, Allison W., Nielsen, Sarah M., Das, Kingshuk, Michalski, Scott, Yang, Shan, Ngo, Nhu, Blanco, Amie, Esplin, Edward D.
Publicado 2020

Universal Germline-Genetic Testing for Breast Cancer: Implementation in a Rural Practice and Impact on Shared Decision-Making

por Shelton, Charles, Ruiz, Antonio, Shelton, Lauren, Montgomery, Hannah, Freas, Karen, Ellsworth, Rachel E., Poll, Sarah, Pineda-Alvarez, Daniel, Heald, Brandie, Esplin, Edward D., Nielsen, Sarah M.
Publicado 2023

Universal Germline Genetic Testing for Hereditary Cancer Syndromes in Patients With Solid Tumor Cancer

por Esplin, Edward D., Nielsen, Sarah M., Bristow, Sara L., Garber, Judy E., Hampel, Heather, Rana, Huma Q., Samadder, N. Jewel, Shore, Neal D., Nussbaum, Robert L.
Publicado 2022

Retrospective Cohort Study on the Limitations of Direct-to-Consumer Genetic Screening in Hereditary Breast and Ovarian Cancer

por Desai, Neelam V., Barrows, Elizabeth D., Nielsen, Sarah M., Hatchell, Kathryn E., Anderson, Michael J., Haverfield, Eden V., Herrera, Blanca, Esplin, Edward D., Lucassen, Anneke, Tung, Nadine M., Isaacs, Claudine
Publicado 2023

Tumor genome analysis includes germline genome: Are we ready for surprises?

por Catenacci, Daniel VT, Amico, Andrea L, Nielsen, Sarah M, Geynisman, Daniel M, Rambo, Brittany, Carey, George B, Gulden, Cassandra, Fackenthal, Jim, Marsh, Robert D, Kindler, Hedy L, Olopade, Olufunmilayo I
Publicado 2015

Rate of Pathogenic Germline Variants in Patients With Lung Cancer

por Sorscher, Steven, LoPiccolo, Jaclyn, Heald, Brandie, Chen, Elaine, Bristow, Sara L., Michalski, Scott T., Nielsen, Sarah M., Lacoste, Alix, Keyder, Emil, Lee, Hayan, Nussbaum, Robert L., Martins, Renato, Esplin, Edward D.
Publicado 2023

Comparison of Germline Genetic Testing Before and After a Medical Policy Covering Universal Testing Among Patients With Colorectal Cancer

por Moretz, Chad, Byfield, Stacey DaCosta, Hatchell, Kathryn E., Dalton, Joline, Onglao, Peter Nicholas, Hang, Lillian, Hansen, Pamela, Radford, Cristi, Nielsen, Sarah M., Heald, Brandie, Munro, Sandra B., Nussbaum, Robert L., Esplin, Edward D.
Publicado 2022

Prevalence and clinical implications of germline mutations among Jordanian patients with ovarian cancer. The Jordanian exploratory cancer genetics (Jo‐ECAG) ovarian study

por Abdel‐Razeq, Hikmat, Al‐Azzam, Khansa, Elemian, Shatha, Abu‐Fares, Hala, Abu Sheikha, Areej, Bani Hani, Hira, Bater, Rayan, Sharaf, Baha’, Heald, Brandie, Esplin, Edward D., Nielsen, Sarah M., Alkyam, Mais, Abujamous, Lama, Al‐Attary, Areej
Publicado 2022

CDH1 germline variants are enriched in patients with colorectal cancer, gastric cancer, and breast cancer

por Adib, Elio, El Zarif, Talal, Nassar, Amin H., Akl, Elie W., Abou Alaiwi, Sarah, Mouhieddine, Tarek H., Esplin, Edward D., Hatchell, Kathryn, Nielsen, Sarah M., Rana, Huma Q., Choueiri, Toni K., Kwiatkowski, David J., Sonpavde, Guru
Publicado 2021

Hematologic toxicity in BRCA1 and BRCA2 mutation carriers during chemotherapy: A retrospective matched cohort study

por West, Allison H., Knollman, Hayley, Dugan, James, Hedeker, Donald, Handorf, Elisabeth A., Nielsen, Sarah M., Bealin, Lisa C., Goldblatt, Lindsay G., Willems, Heather, Daly, Mary B., Afghahi, Anosheh, Olopade, Olufunmilayo I., Hulick, Peter J., Shagisultanova, Elena, Huo, Dezheng, Obeid, Elias, Churpek, Jane E.
Publicado 2019

Germline Pathogenic Variant Prevalence Among Latin American and US Hispanic Individuals Undergoing Testing for Hereditary Breast and Ovarian Cancer: A Cross-Sectional Study

por Ossa Gomez, Carlos Andrés, Achatz, Maria Isabel, Hurtado, Mabel, Sanabria-Salas, María Carolina, Sullcahuaman, Yasser, Chávarri-Guerra, Yanin, Dutil, Julie, Nielsen, Sarah M., Esplin, Edward D., Michalski, Scott T., Bristow, Sara L., Hatchell, Kathryn E., Nussbaum, Robert L., Pineda-Alvarez, Daniel E., Ashton-Prolla, Patricia
Publicado 2022

Clinical Impact of Pathogenic Variants in DNA Damage Repair Genes beyond BRCA1 and BRCA2 in Breast and Ovarian Cancer Patients

por Espinel, Whitney, Champine, Marjan, Hampel, Heather, Jeter, Joanne, Sweet, Kevin, Pilarski, Robert, Pearlman, Rachel, Shane, Kate, Brock, Pamela, Westman, Judith A., Kipnis, Lindsay, Sotelo, Jilliane, Chittenden, Anu, Culver, Samantha, Stopfer, Jill E., Schneider, Katherine A., Sacca, Rosalba, Koeller, Diane R., Gaonkar, Shraddha, Vaccari, Erica, Kane, Sarah, Michalski, Scott T., Yang, Shan, Nielsen, Sarah M., Bristow, Sara L., Lincoln, Stephen E., Nussbaum, Robert L., Esplin, Edward D.
Publicado 2022

Clinical Utility of Universal Germline Genetic Testing for Patients With Breast Cancer

por Whitworth, Pat W., Beitsch, Peter D., Patel, Rakesh, Rosen, Barry, Compagnoni, Gia, Baron, Paul L., Simmons, Rache, Brown, Eric A., Gold, Linsey, Holmes, Dennis, Smith, Linda Ann, Kinney, Michael, Grady, Ian, Clark, Patricia, Barbosa, Karen, Lyons, Samuel, Riley, Lee, Coomer, Cynara, Curcio, Lisa, Ruiz, Antonio, Khan, Sadia, MacDonald, Heather, Hughes, Kevin, Hardwick, Mary Kay, Heald, Brandie, Munro, Sandra B., Nielsen, Sarah M., Esplin, Edward D.
Publicado 2022

Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores

por Lecarpentier, Julie, Silvestri, Valentina, Kuchenbaecker, Karoline B., Barrowdale, Daniel, Dennis, Joe, McGuffog, Lesley, Soucy, Penny, Leslie, Goska, Rizzolo, Piera, Navazio, Anna Sara, Valentini, Virginia, Zelli, Veronica, Lee, Andrew, Amin Al Olama, Ali, Tyrer, Jonathan P., Southey, Melissa, John, Esther M., Conner, Thomas A., Goldgar, David E., Buys, Saundra S., Janavicius, Ramunas, Steele, Linda, Ding, Yuan Chun, Neuhausen, Susan L., Hansen, Thomas V.O., Osorio, Ana, Weitzel, Jeffrey N., Toss, Angela, Medici, Veronica, Cortesi, Laura, Zanna, Ines, Palli, Domenico, Radice, Paolo, Manoukian, Siranoush, Peissel, Bernard, Azzollini, Jacopo, Viel, Alessandra, Cini, Giulia, Damante, Giuseppe, Tommasi, Stefania, Peterlongo, Paolo, Fostira, Florentia, Hamann, Ute, Evans, D. Gareth, Henderson, Alex, Brewer, Carole, Eccles, Diana, Cook, Jackie, Ong, Kai-ren, Walker, Lisa, Side, Lucy E., Porteous, Mary E., Davidson, Rosemarie, Hodgson, Shirley, Frost, Debra, Adlard, Julian, Izatt, Louise, Eeles, Ros, Ellis, Steve, Tischkowitz, Marc, Godwin, Andrew K., Meindl, Alfons, Gehrig, Andrea, Dworniczak, Bernd, Sutter, Christian, Engel, Christoph, Niederacher, Dieter, Steinemann, Doris, Hahnen, Eric, Hauke, Jan, Rhiem, Kerstin, Kast, Karin, Arnold, Norbert, Ditsch, Nina, Wang-Gohrke, Shan, Wappenschmidt, Barbara, Wand, Dorothea, Lasset, Christine, Stoppa-Lyonnet, Dominique, Belotti, Muriel, Damiola, Francesca, Barjhoux, Laure, Mazoyer, Sylvie, Van Heetvelde, Mattias, Poppe, Bruce, De Leeneer, Kim, Claes, Kathleen B.M., de la Hoya, Miguel, Garcia-Barberan, Vanesa, Caldes, Trinidad, Perez Segura, Pedro, Kiiski, Johanna I., Aittomäki, Kristiina, Khan, Sofia, Nevanlinna, Heli, van Asperen, Christi J., Vaszko, Tibor, Kasler, Miklos, Olah, Edith, Balmaña, Judith, Gutiérrez-Enríquez, Sara, Diez, Orland, Teulé, Alex, Izquierdo, Angel, Darder, Esther, Brunet, Joan, Del Valle, Jesús, Feliubadalo, Lidia, Pujana, Miquel Angel, Lazaro, Conxi, Arason, Adalgeir, Agnarsson, Bjarni A., Johannsson, Oskar Th., Barkardottir, Rosa B., Alducci, Elisa, Tognazzo, Silvia, Montagna, Marco, Teixeira, Manuel R., Pinto, Pedro, Spurdle, Amanda B., Holland, Helene, Lee, Jong Won, Lee, Min Hyuk, Lee, Jihyoun, Kim, Sung-Won, Kang, Eunyoung, Kim, Zisun, Sharma, Priyanka, Rebbeck, Timothy R., Vijai, Joseph, Robson, Mark, Lincoln, Anne, Musinsky, Jacob, Gaddam, Pragna, Tan, Yen Y., Berger, Andreas, Singer, Christian F., Loud, Jennifer T., Greene, Mark H., Mulligan, Anna Marie, Glendon, Gord, Andrulis, Irene L., Toland, Amanda Ewart, Senter, Leigha, Bojesen, Anders, Nielsen, Henriette Roed, Skytte, Anne-Bine, Sunde, Lone, Jensen, Uffe Birk, Pedersen, Inge Sokilde, Krogh, Lotte, Kruse, Torben A., Caligo, Maria A., Yoon, Sook-Yee, Teo, Soo-Hwang, von Wachenfeldt, Anna, Huo, Dezheng, Nielsen, Sarah M., Olopade, Olufunmilayo I., Nathanson, Katherine L., Domchek, Susan M., Lorenchick, Christa, Jankowitz, Rachel C., Campbell, Ian, James, Paul, Mitchell, Gillian, Orr, Nick, Park, Sue Kyung, Thomassen, Mads, Offit, Kenneth, Couch, Fergus J., Simard, Jacques, Easton, Douglas F., Chenevix-Trench, Georgia, Schmutzler, Rita K., Antoniou, Antonis C., Ottini, Laura
Publicado 2017