Structure of the CaMKIIδ/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation

por Rellos, Peter, Pike, Ashley C. W., Niesen, Frank H., Salah, Eidarus, Lee, Wen Hwa, von Delft, Frank, Knapp, Stefan
Publicado 2010

X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1)

por Manjasetty, Babu A, Niesen, Frank H, Scheich, Christoph, Roske, Yvette, Goetz, Frank, Behlke, Joachim, Sievert, Volker, Heinemann, Udo, Büssow, Konrad
Publicado 2005

A catalog of human cDNA expression clones and its application to structural genomics

por Büssow, Konrad, Quedenau, Claudia, Sievert, Volker, Tischer, Janett, Scheich, Christoph, Seitz, Harald, Hieke, Brigitte, Niesen, Frank H, Götz, Frank, Harttig, Ulrich, Lehrach, Hans
Publicado 2004

Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites

por Pike, Ashley C W, Rellos, Peter, Niesen, Frank H, Turnbull, Andrew, Oliver, Antony W, Parker, Sirlester A, Turk, Benjamin E, Pearl, Laurence H, Knapp, Stefan
Publicado 2008

Structural Basis for Substrate Specificity in Human Monomeric Carbonyl Reductases

por Pilka, Ewa S., Niesen, Frank H., Lee, Wen Hwa, El-Hawari, Yasser, Dunford, James E., Kochan, Grazyna, Wsol, Vladimir, Martin, Hans-Joerg, Maser, Edmund, Oppermann, Udo
Publicado 2009

High-Affinity Inhibitors of Human NAD(+)-Dependent 15-Hydroxyprostaglandin Dehydrogenase: Mechanisms of Inhibition and Structure-Activity Relationships

por Niesen, Frank H., Schultz, Lena, Jadhav, Ajit, Bhatia, Chitra, Guo, Kunde, Maloney, David J., Pilka, Ewa S., Wang, Minghua, Oppermann, Udo, Heightman, Tom D., Simeonov, Anton
Publicado 2010

A prominent β-hairpin structure in the winged-helix domain of RECQ1 is required for DNA unwinding and oligomer formation

por Lucic, Bojana, Zhang, Ying, King, Oliver, Mendoza-Maldonado, Ramiro, Berti, Matteo, Niesen, Frank H., Burgess-Brown, Nicola A., Pike, Ashley C. W., Cooper, Christopher D. O., Gileadi, Opher, Vindigni, Alessandro
Publicado 2011

Kinase Domain Insertions Define Distinct Roles of CLK Kinases in SR Protein Phosphorylation

por Bullock, Alex N., Das, Sanjan, Debreczeni, Judit É., Rellos, Peter, Fedorov, Oleg, Niesen, Frank H., Guo, Kunde, Papagrigoriou, Evangelos, Amos, Ann L., Cho, Suhyung, Turk, Benjamin E., Ghosh, Gourisankar, Knapp, Stefan
Publicado 2009

The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins

por Gileadi, Opher, Knapp, Stefan, Lee, Wen Hwa, Marsden, Brian D., Müller, Susanne, Niesen, Frank H., Kavanagh, Kathryn L., Ball, Linda J., von Delft, Frank, Doyle, Declan A., Oppermann, Udo C. T., Sundström, Michael
Publicado 2007

DNA Damage in Oocytes Induces a Switch of the Quality Control Factor TAp63α from Dimer to Tetramer

por Deutsch, Gregor B., Zielonka, Elisabeth M., Coutandin, Daniel, Weber, Tobias A., Schäfer, Birgit, Hannewald, Jens, Luh, Laura M., Durst, Florian G., Ibrahim, Mohamed, Hoffmann, Jan, Niesen, Frank H., Sentürk, Aycan, Kunkel, Hana, Brutschy, Bernd, Schleiff, Enrico, Knapp, Stefan, Acker-Palmer, Amparo, Grez, Manuel, McKeon, Frank, Dötsch, Volker
Publicado 2011