Continuous Cultivation as a Tool Toward the Rational Bioprocess Development With Pichia Pastoris Cell Factory

por Nieto-Taype, Miguel Angel, Garcia-Ortega, Xavier, Albiol, Joan, Montesinos-Seguí, José Luis, Valero, Francisco
Publicado 2020

Specific growth rate governs AOX1 gene expression, affecting the production kinetics of Pichia pastoris (Komagataella phaffii) P(AOX1)-driven recombinant producer strains with diff...

por Garrigós-Martínez, Javier, Nieto-Taype, Miguel Angel, Gasset-Franch, Arnau, Montesinos-Seguí, José Luis, Garcia-Ortega, Xavier, Valero, Francisco
Publicado 2019

Rationale‐based selection of optimal operating strategies and gene dosage impact on recombinant protein production in Komagataella phaffii (Pichia pastoris)

por Nieto‐Taype, Miguel Angel, Garrigós‐Martínez, Javier, Sánchez‐Farrando, Marc, Valero, Francisco, Garcia‐Ortega, Xavier, Montesinos‐Seguí, José Luis
Publicado 2019

Enabling growth-decoupled Komagataella phaffii recombinant protein production based on the methanol-free P(DH) promoter

por Bernat-Camps, Núria, Ebner, Katharina, Schusterbauer, Veronika, Fischer, Jasmin Elgin, Nieto-Taype, Miguel Angel, Valero, Francisco, Glieder, Anton, Garcia-Ortega, Xavier
Publicado 2023

Bioprocess performance analysis of novel methanol-independent promoters for recombinant protein production with Pichia pastoris

por Garrigós-Martínez, Javier, Vuoristo, Kiira, Nieto-Taype, Miguel Angel, Tähtiharju, Juha, Uusitalo, Jaana, Tukiainen, Pauliina, Schmid, Christian, Tolstorukov, Ilya, Madden, Knut, Penttilä, Merja, Montesinos-Seguí, José Luis, Valero, Francisco, Glieder, Anton, Garcia-Ortega, Xavier
Publicado 2021