Controlled-Deactivation CB1 Receptor Ligands as a Novel Strategy to Lower Intraocular Pressure

por Miller, Sally, Kulkarni, Shashank, Ciesielski, Alex, Nikas, Spyros P., Mackie, Ken, Makriyannis, Alexandros, Straiker, Alex
Publicado 2018

Chain Substituted Cannabilactones with Selectivity for the CB2 Cannabinoid Receptor

por Alapafuja, Shakiru O., Nikas, Spyros P., Ho, Thanh C., Tong, Fei, Benchama, Othman, Makriyannis, Alexandros
Publicado 2019

Blockade of CB1 or Activation of CB2 Cannabinoid Receptors Is Differentially Efficacious in the Treatment of the Early Pathological Events in Streptozotocin-Induced Diabetic Rats

por Spyridakos, Dimitris, Mastrodimou, Niki, Vemuri, Kiran, Ho, Thanh C., Nikas, Spyros P., Makriyannis, Alexandros, Thermos, Kyriaki
Publicado 2022

Targeting the Endocannabinoid System for Neuroprotection: A (19)F-NMR Study of a Selective FAAH Inhibitor Binding with an Anandamide Carrier Protein, HSA

por Zhuang, Jianqin, Yang, De-Ping, Tian, Xiaoyu, Nikas, Spyros P., Sharma, Rishi, Guo, Jason Jianxin, Makriyannis, Alexandros
Publicado 2013

Synthesis of Functionalized Cannabilactones

por Liu, Yingpeng, Ho, Thanh C., Baradwan, Mohammed, Pascual Lopez-Alberca, Maria, Iliopoulos-Tsoutsouvas, Christos, Nikas, Spyros P., Makriyannis, Alexandros
Publicado 2020

Effects of cannabinoid exposure on short-term memory and medial orbitofrontal cortex function and chemistry in adolescent female rhesus macaques

por Kohut, Stephen J., Cao, Lei, Mintzopolous, Dionyssios, Jiang, Shan, Nikas, Spyros P., Makriyannis, Alexandros, Zou, Chun S., Jensen, J. Eric, Frederick, Blaise B., Bergman, Jack, Kangas, Brian D.
Publicado 2022

Endocannabinoid Metabolome Characterization of Milk from Guatemalan Women Living in the Western Highlands

por Gaitán, Adriana V, Wood, JodiAnne T, Solomons, Noel W, Donohue, Juliana A, Ji, Lipin, Liu, Yingpeng, Nikas, Spyros P, Zhang, Fan, Allen, Lindsay H, Makriyannis, Alexandros, Lammi-Keefe, Carol J
Publicado 2019

Structural basis for activation of CB1 by an endocannabinoid analog

por Krishna Kumar, Kaavya, Robertson, Michael J., Thadhani, Elina, Wang, Haoqing, Suomivuori, Carl-Mikael, Powers, Alexander S., Ji, Lipin, Nikas, Spyros P., Dror, Ron O., Inoue, Asuka, Makriyannis, Alexandros, Skiniotis, Georgios, Kobilka, Brian
Publicado 2023

Probing the Carboxyester Side Chain in Controlled Deactivation (−)-Δ(8)-Tetrahydrocannabinols

por Nikas, Spyros P., Sharma, Rishi, Paronis, Carol A., Kulkarni, Shashank, Thakur, Ganesh A., Hurst, Dow, Wood, JodiAnne T., Gifford, Roger S., Rajarshi, Girija, Liu, Yingpeng, Raghav, Jimit Girish, Guo, Jason Jianxin, Järbe, Torbjörn U.C., Reggio, Patricia H., Bergman, Jack, Makriyannis, Alexandros
Publicado 2014