Discovery and optimization of cardenolides inhibiting HSF1 activation in human colon HCT-116 cancer cells

por Nikotina, Alina D., Koludarova, Lidia, Komarova, Elena Y., Mikhaylova, Elena R., Aksenov, Nikolay D., Suezov, Roman, Kartzev, Viktor G., Margulis, Boris A., Guzhova, Irina V.
Publicado 2018

Extracellular Hsp70 Reduces the Pro-Tumor Capacity of Monocytes/Macrophages Co-Cultivated with Cancer Cells

por Komarova, Elena Y., Marchenko, Larisa V., Zhakhov, Alexander V., Nikotina, Alina D., Aksenov, Nikolay D., Suezov, Roman V., Ischenko, Alexander M., Margulis, Boris A., Guzhova, Irina V.
Publicado 2019

Prevention of High Glucose-Mediated EMT by Inhibition of Hsp70 Chaperone

por Nikotina, Alina D., Vladimirova, Snezhana A., Komarova, Elena Y., Alexeev, Dmitry, Efremov, Sergey, Leonova, Elizaveta, Pavlov, Rostislav, Kartsev, Viktor G., Polonik, Sergey G., Margulis, Boris A., Guzhova, Irina V.
Publicado 2021

Combined Cytotoxic Effect of Inhibitors of Proteostasis on Human Colon Cancer Cells

por Nikotina, Alina D., Vladimirova, Snezhana A., Kokoreva, Nadezhda E., Komarova, Elena Y., Aksenov, Nikolay D., Efremov, Sergey, Leonova, Elizaveta, Pavlov, Rostislav, Kartsev, Viktor G., Zhang, Zhichao, Margulis, Boris A., Guzhova, Irina V.
Publicado 2022

Sensitizing tumor cells to conventional drugs: HSP70 chaperone inhibitors, their selection and application in cancer models

por Lazarev, Vladimir F., Sverchinsky, Dmitry V., Mikhaylova, Elena R., Semenyuk, Pavel I., Komarova, Elena Y., Niskanen, Sergey A., Nikotina, Alina D., Burakov, Anton V., Kartsev, Viktor G., Guzhova, Irina V., Margulis, Boris A.
Publicado 2018

Autocrine regulation of tumor cell repopulation by Hsp70-HMGB1 alarmin complex

por Sverchinsky, Dmitry V., Alhasan, Bashar A., Mikeladze, Marina A., Lazarev, Vladimir F., Kuznetcova, Liubov S., Morshneva, Alisa V., Nikotina, Alina D., Ziewanah, Amr, Koludarova, Lidia V., Starkova, Tatiana Y., Margulis, Boris A., Guzhova, Irina V.
Publicado 2023

Etoposide-Induced Apoptosis in Cancer Cells Can Be Reinforced by an Uncoupled Link between Hsp70 and Caspase-3

por Sverchinsky, Dmitry V., Nikotina, Alina D., Komarova, Elena Y., Mikhaylova, Elena R., Aksenov, Nikolay D., Lazarev, Vladimir F., Mitkevich, Vladimir A., Suezov, Roman, Druzhilovskiy, Dmitry S., Poroikov, Vladimir V., Margulis, Boris A., Guzhova, Irina V.
Publicado 2018

Properties of substances inhibiting aggregation of oxidized GAPDH: Data on the interaction with the enzyme and the impact on its intracellular content

por Lazarev, Vladimir F., Nikotina, Alina D., Semenyuk, Pavel I., Evstafyeva, Diana B., Mikhaylova, Elena R., Muronetz, Vladimir I., Shevtsov, Maxim A., Tolkacheva, Anastasia V., Dobrodumov, Anatoly V., Shavarda, Alexey L., Guzhova, Irina V., Margulis, Boris A.
Publicado 2016

Hsp70-containing extracellular vesicles are capable of activating of adaptive immunity in models of mouse melanoma and colon carcinoma

por Komarova, Elena Y., Suezov, Roman V., Nikotina, Alina D., Aksenov, Nikolay D., Garaeva, Luiza A., Shtam, Tatiana A., Zhakhov, Alexander V., Martynova, Marina G., Bystrova, Olga A., Istomina, Maria S., Ischenko, Alexander M., Margulis, Boris A., Guzhova, Irina V.
Publicado 2021

Extracellular GAPDH Promotes Alzheimer Disease Progression by Enhancing Amyloid-β Aggregation and Cytotoxicity

por Lazarev, Vladimir F, Tsolaki, Magda, Mikhaylova, Elena R, Benken, Konstantin A, Shevtsov, Maxim A, Nikotina, Alina D, Lechpammer, Mirna, Mitkevich, Vladimir A, Makarov, Alexander A, Moskalev, Alexey A, Kozin, Sergey A, Margulis, Boris A, Guzhova, Irina V, Nudler, Evgeny
Publicado 2021