Direct sialic acid 4-OAc substitution by nitrogen, sulfur and carbon nucleophiles with retention of stereochemistry

por Bozzola, Tiago, Nilsson, Ulf J., Ellervik, Ulf
Publicado 2022

Efficient O‐Functionalization of Carbohydrates with Electrophilic Reagents

por Tolnai, Gergely L., Nilsson, Ulf J., Olofsson, Berit
Publicado 2016

Ligand Induced Galectin-3 Protein Self-association

por Lepur, Adriana, Salomonsson, Emma, Nilsson, Ulf J., Leffler, Hakon
Publicado 2012

Sialic Acid 4‐N‐Piperazine and Piperidine Derivatives Bind with High Affinity to the P. mirabilis Sialic Acid Sodium Solute Symporter

por Bozzola, Tiago, Johnsson, Richard E., Nilsson, Ulf J., Ellervik, Ulf
Publicado 2022

Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3′-sulfo-lactose, and 2′-fucosyllactose

por Bum-Erdene, Khuchtumur, Leffler, Hakon, Nilsson, Ulf J., Blanchard, Helen
Publicado 2016

Aminopyrimidine–galactose hybrids are highly selective galectin-3 inhibitors

por Dahlqvist, Alexander, Zetterberg, Fredrik R., Leffler, Hakon, Nilsson, Ulf J.
Publicado 2019

A Galactoside-Binding Protein Tricked into Binding Unnatural Pyranose Derivatives: 3-Deoxy-3-Methyl-Gulosides Selectively Inhibit Galectin-1

por Pal, Kumar Bhaskar, Mahanti, Mukul, Leffler, Hakon, Nilsson, Ulf J.
Publicado 2019

Stereo- and regioselective hydroboration of 1-exo-methylene pyranoses: discovery of aryltriazolylmethyl C-galactopyranosides as selective galectin-1 inhibitors

por Dahlqvist, Alexander, Furevi, Axel, Warlin, Niklas, Leffler, Hakon, Nilsson, Ulf J
Publicado 2019

Mapping the energy landscape of protein–ligand binding via linear free energy relationships determined by protein NMR relaxation dispersion

por Stenström, Olof, Diehl, Carl, Modig, Kristofer, Nilsson, Ulf J., Akke, Mikael
Publicado 2020

Galectin-3 Inhibition by a Small-Molecule Inhibitor Reduces Both Pathological Corneal Neovascularization and Fibrosis

por Chen*, Wei-Sheng, Cao, Zhiyi, Leffler, Hakon, Nilsson, Ulf J., Panjwani, Noorjahan
Publicado 2017

The Anti-angiogenic Peptide Anginex Greatly Enhances Galectin-1 Binding Affinity for Glycoproteins

por Salomonsson, Emma, Thijssen, Victor L., Griffioen, Arjan W., Nilsson, Ulf J., Leffler, Hakon
Publicado 2011

Synthesis of tricyclic carbohydrate–benzene hybrids as selective inhibitors of galectin-1 and galectin-8 N-terminal domains

por Wu, Chunxia, Yong, Can, Zhong, Qiuju, Wang, Zhouyu, Nilsson, Ulf J., Zhang, Yuanyuan
Publicado 2020

Inhibition mechanism of human galectin-7 by a novel galactose-benzylphosphate inhibitor

por Masuyer, Geoffrey, Jabeen, Talat, Öberg, Christopher T, Leffler, Hakon, Nilsson, Ulf J, Acharya, K Ravi
Publicado 2012

Bacterial Adhesion of Streptococcus suis to Host Cells and Its Inhibition by Carbohydrate Ligands

por Kouki, Annika, Pieters, Roland J., Nilsson, Ulf J., Loimaranta, Vuokko, Finne, Jukka, Haataja, Sauli
Publicado 2013

Local delivery of minocycline-loaded PLGA nanoparticles from gelatin-coated neural implants attenuates acute brain tissue responses in mice

por Holmkvist, Alexander Dontsios, Agorelius, Johan, Forni, Matilde, Nilsson, Ulf J., Linsmeier, Cecilia Eriksson, Schouenborg, Jens
Publicado 2020

Ligand Sulfur Oxidation State Progressively Alters Galectin-3-Ligand Complex Conformations To Induce Affinity-Influencing Hydrogen Bonds

por Mahanti, Mukul, Pal, Kumar Bhaskar, Kumar, Rohit, Schulze, Markus, Leffler, Hakon, Logan, Derek T., Nilsson, Ulf J.
Publicado 2023

Design and synthesis of novel 3-triazolyl-1-thiogalactosides as galectin-1, -3 and -8 inhibitors

por van Klaveren, Sjors, Dernovšek, Jaka, Jakopin, Žiga, Anderluh, Marko, Leffler, Hakon, Nilsson, Ulf J., Tomašič, Tihomir
Publicado 2022

Structure and Energetics of Ligand–Fluorine Interactions with Galectin‐3 Backbone and Side‐Chain Amides: Insight into Solvation Effects and Multipolar Interactions

por Kumar, Rohit, Ignjatović, Majda Misini, Peterson, Kristoffer, Olsson, Martin, Leffler, Hakon, Ryde, Ulf, Nilsson, Ulf J., Logan, Derek T.
Publicado 2019

3-Substituted 1-Naphthamidomethyl-C-galactosyls Interact with Two Unique Sub-Sites for High-Affinity and High-Selectivity Inhibition of Galectin-3

por Dahlqvist, Alexander, Mandal, Santanu, Peterson, Kristoffer, Håkansson, Maria, Logan, Derek T., Zetterberg, Fredrik R., Leffler, Hakon, Nilsson, Ulf J.
Publicado 2019

Protein Flexibility and Conformational Entropy in Ligand Design Targeting the Carbohydrate Recognition Domain of Galectin-3

por Diehl, Carl, Engström, Olof, Delaine, Tamara, Håkansson, Maria, Genheden, Samuel, Modig, Kristofer, Leffler, Hakon, Ryde, Ulf, Nilsson, Ulf J., Akke, Mikael
Publicado 2010