Altered Co-Translational Processing Plays a Role in Huntington's Pathogenesis—A Hypothesis

por Nissley, Daniel A., O'Brien, Edward P.
Publicado 2016

Current structure predictors are not learning the physics of protein folding

por Outeiral, Carlos, Nissley, Daniel A, Deane, Charlotte M
Publicado 2022

Ribosome occupancy profiles are conserved between structurally and evolutionarily related yeast domains

por Nissley, Daniel A, Carbery, Anna, Chonofsky, Mark, Deane, Charlotte M
Publicado 2021

Computationally profiling peptide:MHC recognition by T-cell receptors and T-cell receptor-mimetic antibodies

por Raybould, Matthew I. J., Nissley, Daniel A., Kumar, Sandeep, Deane, Charlotte M.
Publicado 2023

Is Posttranslational Folding More Efficient Than Refolding from a Denatured State: A Computational Study

por Vu, Quyen V., Nissley, Daniel A., Jiang, Yang, O’Brien, Edward P., Li, Mai Suan
Publicado 2023

Electrostatic Interactions Explain the Higher Binding Affinity of the CR3022 Antibody for SARS-CoV-2 than the 4A8 Antibody

por Nguyen, Hung, Lan, Pham Dang, Nissley, Daniel A., O’Brien, Edward P., Li, Mai Suan
Publicado 2021

Cocktail of REGN Antibodies Binds More Strongly to SARS-CoV-2 Than Its Components, but the Omicron Variant Reduces Its Neutralizing Ability

por Nguyen, Hung, Lan, Pham Dang, Nissley, Daniel A., O’Brien, Edward P., Li, Mai Suan
Publicado 2022

Accurate prediction of cellular co-translational folding indicates proteins can switch from post- to co-translational folding

por Nissley, Daniel A., Sharma, Ajeet K., Ahmed, Nabeel, Friedrich, Ulrike A., Kramer, Günter, Bukau, Bernd, O'Brien, Edward P.
Publicado 2016

Does SARS-CoV-2 Bind to Human ACE2 More Strongly Than Does SARS-CoV?

por Nguyen, Hoang Linh, Lan, Pham Dang, Thai, Nguyen Quoc, Nissley, Daniel A., O’Brien, Edward P., Li, Mai Suan
Publicado 2020

Universal protein misfolding intermediates can bypass the proteostasis network and remain soluble and less functional

por Nissley, Daniel A., Jiang, Yang, Trovato, Fabio, Sitarik, Ian, Narayan, Karthik B., To, Philip, Xia, Yingzi, Fried, Stephen D., O’Brien, Edward P.
Publicado 2022

How soluble misfolded proteins bypass chaperones at the molecular level

por Halder, Ritaban, Nissley, Daniel A., Sitarik, Ian, Jiang, Yang, Rao, Yiyun, Vu, Quyen V., Li, Mai Suan, Pritchard, Justin, O’Brien, Edward P.
Publicado 2023