Tdp2: A Means to Fixing the Ends

por Nitiss, John L., Nitiss, Karin C.
Publicado 2013

Editorial: The repair of DNA–protein crosslinks

por Sun, Yilun, Nitiss, John L., Pommier, Yves
Publicado 2023

SUMO: A Swiss Army Knife for Eukaryotic Topoisomerases

por Sun, Yilun, Nitiss, John L., Pommier, Yves
Publicado 2022

End-processing during non-homologous end-joining: a role for exonuclease 1

por Bahmed, Karim, Seth, Aman, Nitiss, Karin C., Nitiss, John L.
Publicado 2011

Modeling Allosteric Mechanisms of Eukaryotic Type II Topoisomerases

por Evoli, Stefania, Kariyawasam, Nilusha L., Nitiss, Karin C., Nitiss, John L., Wereszczynski, Jeff
Publicado 2023

Requirements for MRN endonuclease processing of topoisomerase II-mediated DNA damage in mammalian cells

por Sun, Yilun, Soans, Eroica, Mishina, Margarita, Petricci, Elena, Pommier, Yves, Nitiss, Karin C., Nitiss, John L.
Publicado 2022

A complex suite of loci and elements in eukaryotic type II topoisomerases determine selective sensitivity to distinct poisoning agents

por Blower, Tim R, Bandak, Afif, Lee, Amy S Y, Austin, Caroline A, Nitiss, John L, Berger, James M
Publicado 2019

A conserved SUMO pathway repairs topoisomerase DNA-protein cross-links by engaging ubiquitin-mediated proteasomal degradation

por Sun, Yilun, Miller Jenkins, Lisa M., Su, Yijun P., Nitiss, Karin C., Nitiss, John L., Pommier, Yves
Publicado 2020

Kinetic Study of DNA Topoisomerases by Supercoiling-Dependent Fluorescence Quenching

por Wang, Yunke, Rakela, Samantha, Chambers, Jeremy W., Hua, Zi-Chun, Muller, Mark T., Nitiss, John L., Tse-Dinh, Yuk-Ching, Leng, Fenfei
Publicado 2019

Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human cancers

por Boot, Arnoud, Liu, Mo, Stantial, Nicole, Shah, Viraj, Yu, Willie, Nitiss, Karin C., Nitiss, John L., Jinks-Robertson, Sue, Rozen, Steven G.
Publicado 2022

Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity

por Menendez, Daniel, Anand, Jay R., Murphy, Carri C., Bell, Whitney J., Fu, Jiaqi, Slepushkina, Nadia, Buehler, Eugen, Martin, Scott E., Lal-Nag, Madhu, Nitiss, John L., Resnick, Michael A.
Publicado 2022

Aberrant Topoisomerase-1-DNA Lesions are Pathogenic in Neurodegenerative Genome Instability Syndromes

por Katyal, Sachin, Lee, Youngsoo, Nitiss, Karin C., Downing, Susanna M., Li, Yang, Shimada, Mikio, Zhao, Jingfeng, Russell, Helen R., Petrini, John H. J., Nitiss, John L., McKinnon, Peter J.
Publicado 2014

Effects of an unusual poison identify a lifespan role for Topoisomerase 2 in Saccharomyces cerevisiae

por Tombline, Gregory, Millen, Jonathan I., Polevoda, Bogdan, Rapaport, Matan, Baxter, Bonnie, Van Meter, Michael, Gilbertson, Matthew, Madrey, Joe, Piazza, Gary A., Rasmussen, Lynn, Wennerberg, Krister, White, E. Lucile, Nitiss, John L., Goldfarb, David S.
Publicado 2017