The secreted APP ectodomain sAPPα, but not sAPPβ, protects neurons against Aβ oligomer-induced dendritic spine loss and increased tau phosphorylation

por Tackenberg, Christian, Nitsch, Roger M.
Publicado 2019

Recent Developments in Positron Emission Tomography Tracers for Proteinopathies Imaging in Dementia

por Ni, Ruiqing, Nitsch, Roger M.
Publicado 2022

Tau pathology-dependent remodelling of cerebral arteries precedes Alzheimer’s disease-related microvascular cerebral amyloid angiopathy

por Merlini, Mario, Wanner, Debora, Nitsch, Roger M.
Publicado 2016

Familial Alzheimer’s disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vi...

por Tackenberg, Christian, Kulic, Luka, Nitsch, Roger M.
Publicado 2020

Chronic Intranasal Treatment with an Anti-Aβ(30-42) scFv Antibody Ameliorates Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease

por Cattepoel, Susann, Hanenberg, Michael, Kulic, Luka, Nitsch, Roger M.
Publicado 2011

Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice

por Merlini, Mario, Meyer, Eric P., Ulmann-Schuler, Alexandra, Nitsch, Roger M.
Publicado 2011

Oligomeric Forms of Human Amyloid-Beta(1–42) Inhibit Antigen Presentation

por Gericke, Christoph, Mallone, Anna, Engelhardt, Britta, Nitsch, Roger M., Ferretti, Maria Teresa
Publicado 2020

Turnover of Amyloid Precursor Protein Family Members Determines Their Nuclear Signaling Capability

por Gersbacher, Manuel T., Goodger, Zoë V., Trutzel, Annette, Bundschuh, Diana, Nitsch, Roger M., Konietzko, Uwe
Publicado 2013

Visualization and Quantification of APP Intracellular Domain-Mediated Nuclear Signaling by Bimolecular Fluorescence Complementation

por Riese, Florian, Grinschgl, Sonja, Gersbacher, Manuel T., Russi, Natalie, Hock, Christoph, Nitsch, Roger M., Konietzko, Uwe
Publicado 2013

Intraindividual variability across cognitive tasks as a potential marker for prodromal Alzheimer’s disease

por Kälin, Andrea M., Pflüger, Marlon, Gietl, Anton F., Riese, Florian, Jäncke, Lutz, Nitsch, Roger M., Hock, Christoph
Publicado 2014

Reciprocal modulation of Aβ42 aggregation by copper and homocysteine

por Keskitalo, Salla, Farkas, Melinda, Hanenberg, Michael, Szodorai, Anita, Kulic, Luka, Semmler, Alexander, Weller, Michael, Nitsch, Roger M., Linnebank, Michael
Publicado 2014

The amyloid-β degradation intermediate Aβ34 is pericyte-associated and reduced in brain capillaries of patients with Alzheimer’s disease

por Kirabali, Tunahan, Rigotti, Serena, Siccoli, Alessandro, Liebsch, Filip, Shobo, Adeola, Hock, Christoph, Nitsch, Roger M., Multhaup, Gerhard, Kulic, Luka
Publicado 2019

Automatic analysis of skull thickness, scalp-to-cortex distance and association with age and sex in cognitively normal elderly

por Zhang, Junhao, Treyer, Valerie, Sun, Junfeng, Zhang, Chencheng, Gietl, Anton, Hock, Christoph, Razansky, Daniel, Nitsch, Roger M., Ni, Ruiqing
Publicado 2023

Quantification of subcortical gray-matter vascularization using 7 Tesla time-of-flight angiography

por Laurig, Mathias, Liu, Xinyang, Wyss, Michael, Gietl, Anton, Jellestad, Lena, Nitsch, Roger M, Prüssmann, Klaas, Hock, Christoph, Unschuld, Paul G
Publicado 2013

Reduced β-amyloid pathology in an APP transgenic mouse model of Alzheimer’s disease lacking functional B and T cells

por Späni, Claudia, Suter, Tobias, Derungs, Rebecca, Ferretti, Maria Teresa, Welt, Tobias, Wirth, Fabian, Gericke, Christoph, Nitsch, Roger M., Kulic, Luka
Publicado 2015

SWI and phase imaging reveal intracranial calcifications in the P301L mouse model of human tauopathy

por Ni, Ruiqing, Zarb, Yvette, Kuhn, Gisela A., Müller, Ralph, Yundung, Yankey, Nitsch, Roger M., Kulic, Luka, Keller, Annika, Klohs, Jan
Publicado 2020

Age-, sex-, and pathology-related variability in brain structure and cognition

por Bachmann, Dario, Buchmann, Andreas, Studer, Sandro, Saake, Antje, Rauen, Katrin, Zuber, Isabelle, Gruber, Esmeralda, Nitsch, Roger M., Hock, Christoph, Gietl, Anton, Treyer, Valerie
Publicado 2023

APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes

por de Leeuw, Sherida M., Kirschner, Aron W.T., Lindner, Karina, Rust, Ruslan, Budny, Vanessa, Wolski, Witold E., Gavin, Anne-Claude, Nitsch, Roger M., Tackenberg, Christian
Publicado 2021

APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes

por de Leeuw, Sherida M., Kirschner, Aron W.T., Lindner, Karina, Rust, Ruslan, Budny, Vanessa, Wolski, Witold E., Gavin, Anne-Claude, Nitsch, Roger M., Tackenberg, Christian
Publicado 2022

A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells

por Michalon, Aubin, Hagenbuch, Andreas, Huy, Christian, Varela, Evita, Combaluzier, Benoit, Damy, Thibaud, Suhr, Ole B., Saraiva, Maria J., Hock, Christoph, Nitsch, Roger M., Jan Grimm
Publicado 2021