Antimalarial pharmacology and therapeutics of atovaquone

por Nixon, Gemma L., Moss, Darren M., Shone, Alison E., Lalloo, David G., Fisher, Nicholas, O'Neill, Paul M., Ward, Stephen A., Biagini, Giancarlo A.
Publicado 2013

Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library

por Johnston, Kelly L., Cook, Darren A. N., Berry, Neil G., David Hong, W., Clare, Rachel H., Goddard, Megan, Ford, Louise, Nixon, Gemma L., O’Neill, Paul M., Ward, Stephen A., Taylor, Mark J.
Publicado 2017

Repurposing and Reformulation of the Antiparasitic Agent Flubendazole for Treatment of Cryptococcal Meningoencephalitis, a Neglected Fungal Disease

por Nixon, Gemma L., McEntee, Laura, Johnson, Adam, Farrington, Nicola, Whalley, Sarah, Livermore, Joanne, Natal, Cristien, Washbourn, Gina, Bibby, Jaclyn, Berry, Neil, Lestner, Jodi, Truong, Megan, Owen, Andrew, Lalloo, David, Charles, Ian, Hope, William
Publicado 2018

Development of Pyrazolopyrimidine Anti-Wolbachia Agents for the Treatment of Filariasis

por McGillan, Paul, Berry, Neil G., Nixon, Gemma L., Leung, Suet C., Webborn, Peter J. H., Wenlock, Mark C., Kavanagh, Stefan, Cassidy, Andrew, Clare, Rachel H., Cook, Darren A., Johnston, Kelly L., Ford, Louise, Ward, Stephen A., Taylor, Mark J., Hong, W. David, O’Neill, Paul M.
Publicado 2021

Identification, Design and Biological Evaluation of Bisaryl Quinolones Targeting Plasmodium falciparum Type II NADH:Quinone Oxidoreductase (PfNDH2)

por Pidathala, Chandrakala, Amewu, Richard, Pacorel, Bénédicte, Nixon, Gemma L., Gibbons, Peter, Hong, W. David, Leung, Suet C., Berry, Neil G., Sharma, Raman, Stocks, Paul A., Srivastava, Abhishek, Shone, Alison E., Charoensutthivarakul, Sitthivut, Taylor, Lee, Berger, Olivier, Mbekeani, Alison, Hill, Alasdair, Fisher, Nicholas E., Warman, Ashley J., Biagini, Giancarlo A., Ward, Stephen A., O’Neill, Paul M.
Publicado 2012

Identification of Novel Antimalarial Chemotypes via Chemoinformatic Compound Selection Methods for a High-Throughput Screening Program against the Novel Malarial Target, PfNDH2: In...

por Sharma, Raman, Lawrenson, Alexandre S., Fisher, Nicholas E., Warman, Ashley J., Shone, Alison E., Hill, Alasdair, Mbekeani, Alison, Pidathala, Chandrakala, Amewu, Richard K., Leung, Suet, Gibbons, Peter, Hong, David W., Stocks, Paul, Nixon, Gemma L., Chadwick, James, Shearer, Joanne, Gowers, Ian, Cronk, David, Parel, Serge P., O'Neill, Paul M., Ward, Stephen A., Biagini, Giancarlo A., Berry, Neil G.
Publicado 2012

Identification, Design and Biological Evaluation of Heterocyclic Quinolones Targeting Plasmodium falciparum Type II NADH:Quinone Oxidoreductase (PfNDH2)

por Leung, Suet C., Gibbons, Peter, Amewu, Richard, Nixon, Gemma L., Pidathala, Chandrakala, Hong, W. David, Pacorel, Bénédicte, Berry, Neil G., Sharma, Raman, Stocks, Paul A., Srivastava, Abhishek, Shone, Alison E., Charoensutthivarakul, Sitthivut, Taylor, Lee, Berger, Olivier, Mbekeani, Alison, Hill, Alasdair, Fisher, Nicholas E., Warman, Ashley J., Biagini, Giancarlo A., Ward, Stephen A., O’Neill, Paul M.
Publicado 2012

Identification of 2-Aryl-Quinolone Inhibitors of Cytochrome bd and Chemical Validation of Combination Strategies for Respiratory Inhibitors against Mycobacterium tuberculosis

por Jeffreys, Laura N., Ardrey, Alison, Hafiz, Taghreed A., Dyer, Lauri-Anne, Warman, Ashley J., Mosallam, Nada, Nixon, Gemma L., Fisher, Nicholas E., Hong, W. David, Leung, Suet C., Aljayyoussi, Ghaith, Bibby, Jaclyn, Almeida, Deepak V., Converse, Paul J., Fotouhi, Nader, Berry, Neil G., Nuermberger, Eric L., Upton, Anna M., O’Neill, Paul M., Ward, Stephen A., Biagini, Giancarlo A.
Publicado 2023

Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides

por Clare, Rachel H., Bardelle, Catherine, Harper, Paul, Hong, W. David, Börjesson, Ulf, Johnston, Kelly L., Collier, Matthew, Myhill, Laura, Cassidy, Andrew, Plant, Darren, Plant, Helen, Clark, Roger, Cook, Darren A. N., Steven, Andrew, Archer, John, McGillan, Paul, Charoensutthivarakul, Sitthivut, Bibby, Jaclyn, Sharma, Raman, Nixon, Gemma L., Slatko, Barton E., Cantin, Lindsey, Wu, Bo, Turner, Joseph, Ford, Louise, Rich, Kirsty, Wigglesworth, Mark, Berry, Neil G., O’Neill, Paul M., Taylor, Mark J., Ward, Stephen A.
Publicado 2019

AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis

por Hong, W. David, Benayoud, Farid, Nixon, Gemma L., Ford, Louise, Johnston, Kelly L., Clare, Rachel H., Cassidy, Andrew, Cook, Darren A. N., Siu, Amy, Shiotani, Motohiro, Webborn, Peter J. H., Kavanagh, Stefan, Aljayyoussi, Ghaith, Murphy, Emma, Steven, Andrew, Archer, John, Struever, Dominique, Frohberger, Stefan J., Ehrens, Alexandra, Hübner, Marc P., Hoerauf, Achim, Roberts, Adam P., Hubbard, Alasdair T. M., Tate, Edward W., Serwa, Remigiusz A., Leung, Suet C., Qie, Li, Berry, Neil G., Gusovsky, Fabian, Hemingway, Janet, Turner, Joseph D., Taylor, Mark J., Ward, Stephen A., O’Neill, Paul M.
Publicado 2019

A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance

por O'Neill, Paul M., Amewu, Richard K., Charman, Susan A., Sabbani, Sunil, Gnädig, Nina F., Straimer, Judith, Fidock, David A., Shore, Emma R., Roberts, Natalie L., Wong, Michael H.-L., Hong, W. David, Pidathala, Chandrakala, Riley, Chris, Murphy, Ben, Aljayyoussi, Ghaith, Gamo, Francisco Javier, Sanz, Laura, Rodrigues, Janneth, Cortes, Carolina Gonzalez, Herreros, Esperanza, Angulo-Barturén, Iñigo, Jiménez-Díaz, María Belén, Bazaga, Santiago Ferrer, Martínez-Martínez, María Santos, Campo, Brice, Sharma, Raman, Ryan, Eileen, Shackleford, David M., Campbell, Simon, Smith, Dennis A., Wirjanata, Grennady, Noviyanti, Rintis, Price, Ric N., Marfurt, Jutta, Palmer, Michael J., Copple, Ian M., Mercer, Amy E., Ruecker, Andrea, Delves, Michael J., Sinden, Robert E., Siegl, Peter, Davies, Jill, Rochford, Rosemary, Kocken, Clemens H. M., Zeeman, Anne-Marie, Nixon, Gemma L., Biagini, Giancarlo A., Ward, Stephen A.
Publicado 2017