Protective LRRK2 R1398H Variant Enhances GTPase and Wnt Signaling Activity

por Nixon-Abell, Jonathon, Berwick, Daniel C., Grannó, Simone, Spain, Victoria A., Blackstone, Craig, Harvey, Kirsten
Publicado 2016

Multiplex Gene Tagging with CRISPR-Cas9 for Live-Cell Microscopy and Application to Study the Role of SARS-CoV-2 Proteins in Autophagy, Mitochondrial Dynamics, and Cell Growth

por Perez-Leal, Oscar, Nixon-Abell, Jonathon, Barrero, Carlos A., Gordon, John C., Oesterling, James, Rico, Mario C.
Publicado 2021

Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling

por Berwick, Daniel C., Javaheri, Behzad, Wetzel, Andrea, Hopkinson, Mark, Nixon-Abell, Jonathon, Grannò, Simone, Pitsillides, Andrew A., Harvey, Kirsten
Publicado 2017

ER proteins decipher the tubulin code to regulate organelle distribution

por Zheng, Pengli, Obara, Christopher J., Szczesna, Ewa, Nixon-Abell, Jonathon, Mahalingan, Kishore K., Roll-Mecak, Antonina, Lippincott-Schwartz, Jennifer, Blackstone, Craig
Publicado 2021

Publisher Correction: ER proteins decipher the tubulin code to regulate organelle distribution

por Zheng, Pengli, Obara, Christopher J., Szczesna, Ewa, Nixon-Abell, Jonathon, Mahalingan, Kishore K., Roll-Mecak, Antonina, Lippincott-Schwartz, Jennifer, Blackstone, Craig
Publicado 2022

Regulation of membrane fluidity by RNF145‐triggered degradation of the lipid hydrolase ADIPOR2

por Volkmar, Norbert, Gawden‐Bone, Christian M, Williamson, James C, Nixon‐Abell, Jonathon, West, James A, St George‐Hyslop, Peter H, Kaser, Arthur, Lehner, Paul J
Publicado 2022

Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis

por Heaton, George R., Landeck, Natalie, Mamais, Adamantios, Nalls, Mike A., Nixon-Abell, Jonathon, Kumaran, Ravindran, Beilina, Alexandra, Pellegrini, Laura, Li, Yan, Harvey, Kirsten, Cookson, Mark R.
Publicado 2020

Spatially non-uniform condensates emerge from dynamically arrested phase separation

por Erkamp, Nadia A., Sneideris, Tomas, Ausserwöger, Hannes, Qian, Daoyuan, Qamar, Seema, Nixon-Abell, Jonathon, St George-Hyslop, Peter, Schmit, Jeremy D., Weitz, David A., Knowles, Tuomas P. J.
Publicado 2023

Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice

por Pellegrini, Laura, Hauser, David N, Li, Yan, Mamais, Adamantios, Beilina, Alexandra, Kumaran, Ravindran, Wetzel, Andrea, Nixon-Abell, Jonathon, Heaton, George, Rudenko, Iakov, Alkaslasi, Mor, Ivanina, Natalie, Melrose, Heather L, Cookson, Mark R, Harvey, Kirsten
Publicado 2018

Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus

por Granno, Simone, Nixon-Abell, Jonathon, Berwick, Daniel C., Tosh, Justin, Heaton, George, Almudimeegh, Sultan, Nagda, Zenisha, Rain, Jean-Christophe, Zanda, Manuela, Plagnol, Vincent, Tybulewicz, Victor L. J., Cleverley, Karen, Wiseman, Frances K., Fisher, Elizabeth M. C., Harvey, Kirsten
Publicado 2019

Z-α(1)-antitrypsin polymers impose molecular filtration in the endoplasmic reticulum after undergoing phase transition to a solid state

por Chambers, Joseph E., Zubkov, Nikita, Kubánková, Markéta, Nixon-Abell, Jonathon, Mela, Ioanna, Abreu, Susana, Schwiening, Max, Lavarda, Giulia, López-Duarte, Ismael, Dickens, Jennifer A., Torres, Tomás, Kaminski, Clemens F., Holt, Liam J., Avezov, Edward, Huntington, James A., George-Hyslop, Peter St, Kuimova, Marina K., Marciniak, Stefan J.
Publicado 2022

RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether

por Liao, Ya-Cheng, Fernandopulle, Michael S., Wang, Guozhen, Choi, Heejun, Hao, Ling, Drerup, Catherine M., Patel, Rajan, Qamar, Seema, Nixon-Abell, Jonathon, Shen, Yi, Meadows, William, Vendruscolo, Michele, Knowles, Tuomas P.J., Nelson, Matthew, Czekalska, Magdalena A., Musteikyte, Greta, Gachechiladze, Mariam A., Stephens, Christina A., Pasolli, H. Amalia, Forrest, Lucy R., St George-Hyslop, Peter, Lippincott-Schwartz, Jennifer, Ward, Michael E.
Publicado 2019

The importance of naturally attenuated SARS‐CoV‐2in the fight against COVID‐19

por Armengaud, Jean, Delaunay‐Moisan, Agnès, Thuret, Jean‐Yves, van Anken, Eelco, Acosta‐Alvear, Diego, Aragón, Tomás, Arias, Carolina, Blondel, Marc, Braakman, Ineke, Collet, Jean‐François, Courcol, René, Danchin, Antoine, Deleuze, Jean‐François, Lavigne, Jean‐Philippe, Lucas, Sophie, Michiels, Thomas, Moore, Edward R. B., Nixon‐Abell, Jonathon, Rossello‐Mora, Ramon, Shi, Zheng‐Li, Siccardi, Antonio G., Sitia, Roberto, Tillett, Daniel, Timmis, Kenneth N., Toledano, Michel B., van der Sluijs, Peter, Vicenzi, Elisa
Publicado 2020