Privileged Scaffolds for Potent and Specific Inhibitors of Mono-ADP-Ribosylating PARPs

por Nizi, Maria Giulia, Sarnari, Chiara, Tabarrini, Oriana
Publicado 2023

Medicinal Chemistry Perspective on Targeting Mono-ADP-Ribosylating PARPs with Small Molecules

por Nizi, Maria Giulia, Maksimainen, Mirko M., Lehtiö, Lari, Tabarrini, Oriana
Publicado 2022

Inhibition of Influenza Virus Polymerase by Interfering with Its Protein–Protein Interactions

por Massari, Serena, Desantis, Jenny, Nizi, Maria Giulia, Cecchetti, Violetta, Tabarrini, Oriana
Publicado 2020

Synthesis and characterization of 1,2,4-triazolo[1,5-a]pyrimidine-2-carboxamide-based compounds targeting the PA-PB1 interface of influenza A virus polymerase

por Massari, Serena, Bertagnin, Chiara, Pismataro, Maria Chiara, Donnadio, Anna, Nannetti, Giulio, Felicetti, Tommaso, Di Bona, Stefano, Nizi, Maria Giulia, Tensi, Leonardo, Manfroni, Giuseppe, Loza, Maria Isabel, Sabatini, Stefano, Cecchetti, Violetta, Brea, Jose, Goracci, Laura, Loregian, Arianna, Tabarrini, Oriana
Publicado 2021

[1,2,4]Triazolo[3,4-b]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes

por Murthy, Sudarshan, Nizi, Maria Giulia, Maksimainen, Mirko M., Massari, Serena, Alaviuhkola, Juho, Lippok, Barbara E., Vagaggini, Chiara, Sowa, Sven T., Galera-Prat, Albert, Ashok, Yashwanth, Venkannagari, Harikanth, Prunskaite-Hyyryläinen, Renata, Dreassi, Elena, Lüscher, Bernhard, Korn, Patricia, Tabarrini, Oriana, Lehtiö, Lari
Publicado 2023

Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity

por Nizi, Maria Giulia, Persoons, Leentje, Corona, Angela, Felicetti, Tommaso, Cernicchi, Giada, Massari, Serena, Manfroni, Giuseppe, Vangeel, Laura, Barreca, Maria Letizia, Esposito, Francesca, Jochmans, Dirk, Milia, Jessica, Cecchetti, Violetta, Schols, Dominique, Neyts, Johan, Tramontano, Enzo, Sabatini, Stefano, De Jonghe, Steven, Tabarrini, Oriana
Publicado 2022