Binding of ATP at the active site of human pancreatic glucokinase – nucleotide-induced conformational changes with possible implications for its kinetic cooperativity

por Molnes, Janne, Teigen, Knut, Aukrust, Ingvild, Bjørkhaug, Lise, Søvik, Oddmund, Flatmark, Torgeir, Njølstad, Pål Rasmus
Publicado 2011

Structural properties of the HNF-1A transactivation domain

por Kind, Laura, Driver, Mark, Raasakka, Arne, Onck, Patrick R., Njølstad, Pål Rasmus, Arnesen, Thomas, Kursula, Petri
Publicado 2023

The Composite Autonomic Symptom Score 31 Questionnaire: A Sensitive Test to Detect Risk for Autonomic Neuropathy

por Meling, Sondre, Tjora, Erling, Eichele, Heike, Ejskjaer, Niels, Carlsen, Siri, Njølstad, Pål Rasmus, Brock, Christina, Søfteland, Eirik
Publicado 2023

Structural and biophysical characterization of transcription factor HNF-1A as a tool to study MODY3 diabetes variants

por Kind, Laura, Raasakka, Arne, Molnes, Janne, Aukrust, Ingvild, Bjørkhaug, Lise, Njølstad, Pål Rasmus, Kursula, Petri, Arnesen, Thomas
Publicado 2022

Extending protein interaction networks using proteoforms and small molecules

por Hernández Sánchez, Luis Francisco, Burger, Bram, Castro Campos, Rodrigo Alexander, Johansson, Stefan, Njølstad, Pål Rasmus, Barsnes, Harald, Vaudel, Marc
Publicado 2023

PathwayMatcher: proteoform-centric network construction enables fine-granularity multiomics pathway mapping

por Sánchez, Luis Francisco Hernández, Burger, Bram, Horro, Carlos, Fabregat, Antonio, Johansson, Stefan, Njølstad, Pål Rasmus, Barsnes, Harald, Hermjakob, Henning, Vaudel, Marc
Publicado 2019

Maternal and offspring genetic risk score analyses of fetal alcohol exposure and attention‐deficit hyperactivity disorder risk in offspring

por Haan, Elis, Sallis, Hannah M., Ystrom, Eivind, Njølstad, Pål Rasmus, Andreassen, Ole A., Reichborn‐Kjennerud, Ted, Munafò, Marcus R., Havdahl, Alexandra, Zuccolo, Luisa
Publicado 2021

Functional Investigations of HNF1A Identify Rare Variants as Risk Factors for Type 2 Diabetes in the General Population

por Najmi, Laeya Abdoli, Aukrust, Ingvild, Flannick, Jason, Molnes, Janne, Burtt, Noel, Molven, Anders, Groop, Leif, Altshuler, David, Johansson, Stefan, Bjørkhaug, Lise, Njølstad, Pål Rasmus
Publicado 2017

Assessing the Causal Relationship of Maternal Height on Birth Size and Gestational Age at Birth: A Mendelian Randomization Analysis

por Zhang, Ge, Bacelis, Jonas, Lengyel, Candice, Teramo, Kari, Hallman, Mikko, Helgeland, Øyvind, Johansson, Stefan, Myhre, Ronny, Sengpiel, Verena, Njølstad, Pål Rasmus, Jacobsson, Bo, Muglia, Louis
Publicado 2015

Population prevalence and inheritance pattern of recurrent CNVs associated with neurodevelopmental disorders in 12,252 newborns and their parents

por Smajlagić, Dinka, Lavrichenko, Ksenia, Berland, Siren, Helgeland, Øyvind, Knudsen, Gun Peggy, Vaudel, Marc, Haavik, Jan, Knappskog, Per Morten, Njølstad, Pål Rasmus, Houge, Gunnar, Johansson, Stefan
Publicado 2020

Sonographic pancreas echogenicity in cystic fibrosis compared to exocrine pancreatic function and pancreas fat content at Dixon-MRI

por Engjom, Trond, Kavaliauskiene, Giedre, Tjora, Erling, Erchinger, Friedemann, Wathle, Gaute, Lærum, Birger Norderud, Njølstad, Pål Rasmus, Frøkjær, Jens Brøndum, Gilja, Odd Helge, Dimcevski, Georg, Haldorsen, Ingfrid Salvesen
Publicado 2018

Intrauterine Growth and Offspring Neurodevelopmental Traits: A Mendelian Randomization Analysis of the Norwegian Mother, Father and Child Cohort Study (MoBa)

por D’Urso, Shannon, Moen, Gunn-Helen, Hwang, Liang-Dar, Hannigan, Laurie J., Corfield, Elizabeth C., Ask, Helga, Johannson, Stefan, Njølstad, Pål Rasmus, Beaumont, Robin N., Freathy, Rachel M., Evans, David M., Havdahl, Alexandra
Publicado 2023

Subtype-Specific Surface Proteins on Adipose Tissue Macrophages and Their Association to Obesity-Induced Insulin Resistance

por Strand, Kristina, Stiglund, Natalie, Haugstøyl, Martha Eimstad, Kamyab, Zahra, Langhelle, Victoria, Lawrence-Archer, Laurence, Busch, Christian, Cornillet, Martin, Hjellestad, Iren Drange, Nielsen, Hans Jørgen, Njølstad, Pål Rasmus, Mellgren, Gunnar, Björkström, Niklas K., Fernø, Johan
Publicado 2022

Developmental milestones in early childhood and genetic liability to neurodevelopmental disorders

por Hannigan, Laurie J., Askeland, Ragna Bugge, Ask, Helga, Tesli, Martin, Corfield, Elizabeth, Ayorech, Ziada, Magnus, Per, Njølstad, Pål Rasmus, Øyen, Anne-Siri, Stoltenberg, Camilla, Andreassen, Ole A., Ronald, Angelica, Smith, George Davey, Reichborn-Kjennerud, Ted, Havdahl, Alexandra
Publicado 2023

Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth

por Helgeland, Øyvind, Vaudel, Marc, Juliusson, Petur B., Lingaas Holmen, Oddgeir, Juodakis, Julius, Bacelis, Jonas, Jacobsson, Bo, Lindekleiv, Haakon, Hveem, Kristian, Lie, Rolv Terje, Knudsen, Gun Peggy, Stoltenberg, Camilla, Magnus, Per, Sagen, Jørn V., Molven, Anders, Johansson, Stefan, Njølstad, Pål Rasmus
Publicado 2019

Unsupervised Clustering of Missense Variants in HNF1A Using Multidimensional Functional Data Aids Clinical Interpretation

por Althari, Sara, Najmi, Laeya A., Bennett, Amanda J., Aukrust, Ingvild, Rundle, Jana K., Colclough, Kevin, Molnes, Janne, Kaci, Alba, Nawaz, Sameena, van der Lugt, Timme, Hassanali, Neelam, Mahajan, Anubha, Molven, Anders, Ellard, Sian, McCarthy, Mark I., Bjørkhaug, Lise, Njølstad, Pål Rasmus, Gloyn, Anna L.
Publicado 2020

Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis

por Fjeld, Karianne, Beer, Sebastian, Johnstone, Marianne, Zimmer, Constantin, Mössner, Joachim, Ruffert, Claudia, Krehan, Mario, Zapf, Christian, Njølstad, Pål Rasmus, Johansson, Stefan, Bugert, Peter, Miyajima, Fabio, Liloglou, Triantafillos, Brown, Laura J., Winn, Simon A., Davies, Kelly, Latawiec, Diane, Gunson, Bridget K., Criddle, David N., Pirmohamed, Munir, Grützmann, Robert, Michl, Patrick, Greenhalf, William, Molven, Anders, Sutton, Robert, Rosendahl, Jonas
Publicado 2016

A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland

por Thuesen, Anne Cathrine Baun, Stæger, Frederik Filip, Kaci, Alba, Solheim, Marie Holm, Aukrust, Ingvild, Jørsboe, Emil, Santander, Cindy G., Andersen, Mette K., Li, Zilong, Gilly, Arthur, Stinson, Sara Elizabeth, Gjesing, Anette Prior, Bjerregaard, Peter, Pedersen, Michael Lynge, Larsen, Christina Viskum Lytken, Grarup, Niels, Jørgensen, Marit E., Zeggini, Eleftheria, Bjørkhaug, Lise, Njølstad, Pål Rasmus, Albrechtsen, Anders, Moltke, Ida, Hansen, Torben
Publicado 2022

Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects

por Howe, Laurence J., Nivard, Michel G., Morris, Tim T., Hansen, Ailin F., Rasheed, Humaira, Cho, Yoonsu, Chittoor, Geetha, Ahlskog, Rafael, Lind, Penelope A., Palviainen, Teemu, van der Zee, Matthijs D., Cheesman, Rosa, Mangino, Massimo, Wang, Yunzhang, Li, Shuai, Klaric, Lucija, Ratliff, Scott M., Bielak, Lawrence F., Nygaard, Marianne, Giannelis, Alexandros, Willoughby, Emily A., Reynolds, Chandra A., Balbona, Jared V., Andreassen, Ole A., Ask, Helga, Baras, Aris, Bauer, Christopher R., Boomsma, Dorret I., Campbell, Archie, Campbell, Harry, Chen, Zhengming, Christofidou, Paraskevi, Corfield, Elizabeth, Dahm, Christina C., Dokuru, Deepika R., Evans, Luke M., de Geus, Eco J. C., Giddaluru, Sudheer, Gordon, Scott D., Harden, K. Paige, Hill, W. David, Hughes, Amanda, Kerr, Shona M., Kim, Yongkang, Kweon, Hyeokmoon, Latvala, Antti, Lawlor, Deborah A., Li, Liming, Lin, Kuang, Magnus, Per, Magnusson, Patrik K. E., Mallard, Travis T., Martikainen, Pekka, Mills, Melinda C., Njølstad, Pål Rasmus, Overton, John D., Pedersen, Nancy L., Porteous, David J., Reid, Jeffrey, Silventoinen, Karri, Southey, Melissa C., Stoltenberg, Camilla, Tucker-Drob, Elliot M., Wright, Margaret J., Hewitt, John K., Keller, Matthew C., Stallings, Michael C., Lee, James J., Christensen, Kaare, Kardia, Sharon L. R., Peyser, Patricia A., Smith, Jennifer A., Wilson, James F., Hopper, John L., Hägg, Sara, Spector, Tim D., Pingault, Jean-Baptiste, Plomin, Robert, Havdahl, Alexandra, Bartels, Meike, Martin, Nicholas G., Oskarsson, Sven, Justice, Anne E., Millwood, Iona Y., Hveem, Kristian, Naess, Øyvind, Willer, Cristen J., Åsvold, Bjørn Olav, Koellinger, Philipp D., Kaprio, Jaakko, Medland, Sarah E., Walters, Robin G., Benjamin, Daniel J., Turley, Patrick, Evans, David M., Davey Smith, George, Hayward, Caroline, Brumpton, Ben, Hemani, Gibran, Davies, Neil M.
Publicado 2022

Genetic association study of childhood aggression across raters, instruments, and age

por Ip, Hill F., van der Laan, Camiel M., Krapohl, Eva M. L., Brikell, Isabell, Sánchez-Mora, Cristina, Nolte, Ilja M., St Pourcain, Beate, Bolhuis, Koen, Palviainen, Teemu, Zafarmand, Hadi, Colodro-Conde, Lucía, Gordon, Scott, Zayats, Tetyana, Aliev, Fazil, Jiang, Chang, Wang, Carol A., Saunders, Gretchen, Karhunen, Ville, Hammerschlag, Anke R., Adkins, Daniel E., Border, Richard, Peterson, Roseann E., Prinz, Joseph A., Thiering, Elisabeth, Seppälä, Ilkka, Vilor-Tejedor, Natàlia, Ahluwalia, Tarunveer S., Day, Felix R., Hottenga, Jouke-Jan, Allegrini, Andrea G., Rimfeld, Kaili, Chen, Qi, Lu, Yi, Martin, Joanna, Soler Artigas, María, Rovira, Paula, Bosch, Rosa, Español, Gemma, Ramos Quiroga, Josep Antoni, Neumann, Alexander, Ensink, Judith, Grasby, Katrina, Morosoli, José J., Tong, Xiaoran, Marrington, Shelby, Middeldorp, Christel, Scott, James G., Vinkhuyzen, Anna, Shabalin, Andrey A., Corley, Robin, Evans, Luke M., Sugden, Karen, Alemany, Silvia, Sass, Lærke, Vinding, Rebecca, Ruth, Kate, Tyrrell, Jess, Davies, Gareth E., Ehli, Erik A., Hagenbeek, Fiona A., De Zeeuw, Eveline, Van Beijsterveldt, Toos C.E.M., Larsson, Henrik, Snieder, Harold, Verhulst, Frank C., Amin, Najaf, Whipp, Alyce M., Korhonen, Tellervo, Vuoksimaa, Eero, Rose, Richard J., Uitterlinden, André G., Heath, Andrew C., Madden, Pamela, Haavik, Jan, Harris, Jennifer R., Helgeland, Øyvind, Johansson, Stefan, Knudsen, Gun Peggy S., Njolstad, Pal Rasmus, Lu, Qing, Rodriguez, Alina, Henders, Anjali K., Mamun, Abdullah, Najman, Jackob M., Brown, Sandy, Hopfer, Christian, Krauter, Kenneth, Reynolds, Chandra, Smolen, Andrew, Stallings, Michael, Wadsworth, Sally, Wall, Tamara L., Silberg, Judy L., Miller, Allison, Keltikangas-Järvinen, Liisa, Hakulinen, Christian, Pulkki-Råback, Laura, Havdahl, Alexandra, Magnus, Per, Raitakari, Olli T., Perry, John R. B., Llop, Sabrina, Lopez-Espinosa, Maria-Jose, Bønnelykke, Klaus, Bisgaard, Hans, Sunyer, Jordi, Lehtimäki, Terho, Arseneault, Louise, Standl, Marie, Heinrich, Joachim, Boden, Joseph, Pearson, John, Horwood, L. John, Kennedy, Martin, Poulton, Richie, Eaves, Lindon J., Maes, Hermine H., Hewitt, John, Copeland, William E., Costello, Elizabeth J., Williams, Gail M., Wray, Naomi, Järvelin, Marjo-Riitta, McGue, Matt, Iacono, William, Caspi, Avshalom, Moffitt, Terrie E., Whitehouse, Andrew, Pennell, Craig E., Klump, Kelly L., Burt, S. Alexandra, Dick, Danielle M., Reichborn-Kjennerud, Ted, Martin, Nicholas G., Medland, Sarah E., Vrijkotte, Tanja, Kaprio, Jaakko, Tiemeier, Henning, Davey Smith, George, Hartman, Catharina A., Oldehinkel, Albertine J., Casas, Miquel, Ribasés, Marta, Lichtenstein, Paul, Lundström, Sebastian, Plomin, Robert, Bartels, Meike, Nivard, Michel G., Boomsma, Dorret I.
Publicado 2021