Toward Stability Enhancement of NTS(1)R-Targeted Radioligands: Structural Interventions on [(99m)Tc]Tc-DT1

por Kanellopoulos, Panagiotis, Nock, Berthold A., Krenning, Eric P., Maina, Theodosia
Publicado 2023

Optimizing the Profile of [(99m)Tc]Tc–NT(7–13) Tracers in Pancreatic Cancer Models by Means of Protease Inhibitors

por Kanellopoulos, Panagiotis, Nock, Berthold A., Krenning, Eric P., Maina, Theodosia
Publicado 2020

Peptide Radioligands in Cancer Theranostics: Agonists and Antagonists

por Nock, Berthold A., Kanellopoulos, Panagiotis, Joosten, Lieke, Mansi, Rosalba, Maina, Theodosia
Publicado 2023

Side-Chain Modified [(99m)Tc]Tc-DT1 Mimics: A Comparative Study in NTS(1)R-Positive Models

por Kanellopoulos, Panagiotis, Nock, Berthold A., Rouchota, Maritina, Loudos, George, Krenning, Eric P., Maina, Theodosia
Publicado 2023

[(68)Ga]Ga-DATA(5m)-LM4, a PET Radiotracer in the Diagnosis of SST(2)R-Positive Tumors: Preclinical and First Clinical Results

por Kanellopoulos, Panagiotis, Nock, Berthold A., Greifenstein, Lukas, Baum, Richard P., Roesch, Frank, Maina, Theodosia
Publicado 2022

Preclinical Characterization of a Stabilized Gastrin-Releasing Peptide Receptor Antagonist for Targeted Cancer Theranostics

por Abouzayed, Ayman, Kanellopoulos, Panagiotis, Gorislav, Alisa, Tolmachev, Vladimir, Maina, Theodosia, Nock, Berthold A., Orlova, Anna
Publicado 2023

Key-Protease Inhibition Regimens Promote Tumor Targeting of Neurotensin Radioligands

por Kanellopoulos, Panagiotis, Kaloudi, Aikaterini, de Jong, Marion, Krenning, Eric P., Nock, Berthold A., Maina, Theodosia
Publicado 2020

Impact of clinically tested NEP/ACE inhibitors on tumor uptake of [(111)In-DOTA]MG11—first estimates for clinical translation

por Kaloudi, Aikaterini, Nock, Berthold A., Lymperis, Emmanouil, Valkema, Roelf, Krenning, Eric P., de Jong, Marion, Maina, Theodosia
Publicado 2016

Comparing Gly(11)/dAla(11)-Replacement vs. the in-Situ Neprilysin-Inhibition Approach on the Tumor-targeting Efficacy of the (111)In-SB3/(111)In-SB4 Radiotracer Pair

por Lymperis, Emmanouil, Kaloudi, Aikaterini, Kanellopoulos, Panagiotis, de Jong, Marion, Krenning, Eric P., Nock, Berthold A., Maina, Theodosia
Publicado 2019

[(99m)Tc]Tc-DB1 Mimics with Different-Length PEG Spacers: Preclinical Comparison in GRPR-Positive Models

por Kanellopoulos, Panagiotis, Lymperis, Emmanouil, Kaloudi, Aikaterini, de Jong, Marion, Krenning, Eric P., Nock, Berthold A., Maina, Theodosia
Publicado 2020

Radiolabeled Bombesin Analogs

por Mansi, Rosalba, Nock, Berthold A., Dalm, Simone U., Busstra, Martijn B., van Weerden, Wytske M., Maina, Theodosia
Publicado 2021

One Step Closer to Clinical Translation: Enhanced Tumor Targeting of [(99m)Tc]Tc-DB4 and [(111)In]In-SG4 in Mice Treated with Entresto

por Kanellopoulos, Panagiotis, Kaloudi, Aikaterini, Rouchota, Maritina, Loudos, George, de Jong, Marion, Krenning, Eric P., Nock, Berthold A., Maina, Theodosia
Publicado 2020

[(99m)Tc]Tc-DB15 in GRPR-Targeted Tumor Imaging with SPECT: From Preclinical Evaluation to the First Clinical Outcomes

por Nock, Berthold A., Kaloudi, Aikaterini, Kanellopoulos, Panagiotis, Janota, Barbara, Bromińska, Barbara, Iżycki, Dariusz, Mikołajczak, Renata, Czepczynski, Rafał, Maina, Theodosia
Publicado 2021

Nonpeptidic Z360-Analogs Tagged with Trivalent Radiometals as Anti-CCK(2)R Cancer Theranostic Agents: A Preclinical Study

por Nock, Berthold A., Kanellopoulos, Panagiotis, Chepurny, Oleg G., Rouchota, Maritina, Loudos, George, Holz, George G., Krenning, Eric P., Maina, Theodosia
Publicado 2022

[(111)In-DOTA]Somatostatin-14 analogs as potential pansomatostatin-like radiotracers - first results of a preclinical study

por Tatsi, Aikaterini, Maina, Theodosia, Cescato, Renzo, Waser, Beatrice, Krenning, Eric P, de Jong, Marion, Cordopatis, Paul, Reubi, Jean Claude, Nock, Berthold A
Publicado 2012

NeoBOMB1, a GRPR-Antagonist for Breast Cancer Theragnostics: First Results of a Preclinical Study with [(67)Ga]NeoBOMB1 in T-47D Cells and Tumor-Bearing Mice

por Kaloudi, Aikaterini, Lymperis, Emmanouil, Giarika, Athina, Dalm, Simone, Orlandi, Francesca, Barbato, Donato, Tedesco, Mattia, Maina, Theodosia, de Jong, Marion, Nock, Berthold A.
Publicado 2017

Localization of (99m)Tc-GRP Analogs in GRPR-Expressing Tumors: Effects of Peptide Length and Neprilysin Inhibition on Biological Responses

por Kaloudi, Aikaterini, Lymperis, Emmanouil, Kanellopoulos, Panagiotis, Waser, Beatrice, de Jong, Marion, Krenning, Eric P., Reubi, Jean Claude, Nock, Berthold A., Maina, Theodosia
Publicado 2019

[(111)In]In/[(177)Lu]Lu-AAZTA(5)-LM4 SST(2)R-Antagonists in Cancer Theranostics: From Preclinical Testing to First Patient Results

por Nock, Berthold A., Kanellopoulos, Panagiotis, Moon, Euy Sung, Rouchota, Maritina, Loudos, George, Ballal, Sanjana, Yadav, Madhav P., Bal, Chandrasekhar, Mishra, Prashant, Sheokand, Parvind, Roesch, Frank, Maina, Theodosia
Publicado 2023

In Vivo Stabilized SB3, an Attractive GRPR Antagonist, for Pre- and Intra-Operative Imaging for Prostate Cancer

por Bakker, Ingrid L., van Tiel, Sandra T., Haeck, Joost, Doeswijk, Gabriela N., de Blois, Erik, Segbers, Marcel, Maina, Theodosia, Nock, Berthold A., de Jong, Marion, Dalm, Simone U.
Publicado 2018

Instant kit preparation of (68)Ga-radiopharmaceuticals via the hybrid chelator DATA: clinical translation of [(68)Ga]Ga-DATA-TOC

por Sinnes, Jean-Philippe, Nagel, Johannes, Waldron, Bradley P., Maina, Theodosia, Nock, Berthold A., Bergmann, Ralf K., Ullrich, Martin, Pietzsch, Jens, Bachmann, Michael, Baum, Richard P., Rösch, Frank
Publicado 2019