Effect of Elagolix Exposure on Clinical Efficacy End Points in Phase III Trials in Women With Endometriosis‐Associated Pain: An Application of Markov Model

por Winzenborg, Insa, Polepally, Akshanth R., Nader, Ahmed, Mostafa, Nael M., Noertersheuser, Peter, Ng, Juki
Publicado 2020

Population Pharmacokinetics of Elagolix in Combination with Low-Dose Estradiol/Norethindrone Acetate in Women with Uterine Fibroids

por Beck, Denise, Winzenborg, Insa, Liu, Mohan, Degner, Jacob, Mostafa, Nael M., Noertersheuser, Peter, Shebley, Mohamad
Publicado 2021

Population Pharmacokinetics of Upadacitinib Using the Immediate-Release and Extended-Release Formulations in Healthy Subjects and Subjects with Rheumatoid Arthritis: Analyses of Ph...

por Klünder, Ben, Mittapalli, Rajendar K., Mohamed, Mohamed-Eslam F., Friedel, Anna, Noertersheuser, Peter, Othman, Ahmed A.
Publicado 2019

Exposure–Response Analyses of Upadacitinib Efficacy and Safety in Phase II and III Studies to Support Benefit–Risk Assessment in Rheumatoid Arthritis

por Nader, Ahmed, Mohamed, Mohamed‐Eslam F., Winzenborg, Insa, Doelger, Eva, Noertersheuser, Peter, Pangan, Aileen L., Othman, Ahmed A.
Publicado 2019

Integrating real‐world data and modeling to project changes in femoral neck bone mineral density and fracture risk in premenopausal women

por Beck, Denise, Winzenborg, Insa, Gao, Wei, Mostafa, Nael M., Noertersheuser, Peter, Chiuve, Stephanie E., Owens, Charlotte, Shebley, Mohamad
Publicado 2021

Exposure‐Safety Analyses Identify Predictors of Change in Bone Mineral Density and Support Elagolix Labeling for Endometriosis‐Associated Pain

por Abbas Suleiman, Ahmed, Nader, Ahmed, Winzenborg, Insa, Beck, Denise, Polepally, Akshanth R., Ng, Juki, Noertersheuser, Peter, Mostafa, Nael M.
Publicado 2020

Validation of a quantitative systems pharmacology model of calcium homeostasis using elagolix Phase 3 clinical trial data in women with endometriosis

por Stodtmann, Sven, Nader, Ahmed, Polepally, Akshanth R., Suleiman, Ahmed A., Winzenborg, Insa, Noertersheuser, Peter, Ng, Juki, Mostafa, Nael M., Shebley, Mohamad
Publicado 2021

Clinical Pharmacology of Elagolix: An Oral Gonadotropin-Releasing Hormone Receptor Antagonist for Endometriosis

por Shebley, Mohamad, Polepally, Akshanth R., Nader, Ahmed, Ng, Juki W., Winzenborg, Insa, Klein, Cheri E., Noertersheuser, Peter, Gibbs, Megan A., Mostafa, Nael M.
Publicado 2019