Impact of intravenous infusion time on AAV8 vector pharmacokinetics, safety, and liver transduction in cynomolgus macaques

por Greig, Jenny A, Nordin, Jayme ML, Bote, Erin, Makaron, Leah, Garnett, Mason E, Kattenhorn, Lisa M, Bell, Peter, Goode, Tamara, Wilson, James M
Publicado 2016

Determining the Minimally Effective Dose of a Clinical Candidate AAV Vector in a Mouse Model of Crigler-Najjar Syndrome

por Greig, Jenny A., Nordin, Jayme M.L., Draper, Christine, McMenamin, Deirdre, Chroscinski, Edward A., Bell, Peter, Gray, John T., Richman, Laura K., Wilson, James M.
Publicado 2018

Determining the Minimally Effective Dose of a Clinical Candidate Adeno-Associated Virus Vector in a Mouse Model of Hemophilia A

por Greig, Jenny A., Smith, Melanie K., Nordin, Jayme M.L., Goode, Tamara, Chroscinski, Edward A., Buza, Elizabeth L., Schmidt, Nicole, Kattenhorn, Lisa M., Wadsworth, Samuel, Wilson, James M.
Publicado 2022

AAV8 Gene Therapy for Crigler-Najjar Syndrome in Macaques Elicited Transgene T Cell Responses That Are Resident to the Liver

por Greig, Jenny A., Calcedo, Roberto, Kuri-Cervantes, Leticia, Nordin, Jayme M.L., Albrecht, Jessica, Bote, Erin, Goode, Tamara, Chroscinski, Edward A., Bell, Peter, Richman, Laura K., Betts, Michael R., Wilson, James M.
Publicado 2018