Transfection reagents affect Extracellular Vesicle cargo transfer to recipient cells: The importance of appropriate controls in EV research

por Nordin, Joel Z.
Publicado 2022

Efficient Peptide-Mediated In Vitro Delivery of Cas9 RNP

por Gustafsson, Oskar, Rädler, Julia, Roudi, Samantha, Lehto, Tõnis, Hällbrink, Mattias, Lehto, Taavi, Gupta, Dhanu, Andaloussi, Samir EL, Nordin, Joel Z.
Publicado 2021

Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography

por Corso, Giulia, Mäger, Imre, Lee, Yi, Görgens, André, Bultema, Jarred, Giebel, Bernd, Wood, Matthew J. A., Nordin, Joel Z., Andaloussi, Samir EL
Publicado 2017

Extracellular vesicles are the primary source of blood‐borne tumour‐derived mutant KRAS DNA early in pancreatic cancer

por Hagey, Daniel W., Kordes, Maximilian, Görgens, André, Mowoe, Metoboroghene O., Nordin, Joel Z., Moro, Carlos Fernández, Löhr, J.‐Matthias, EL Andaloussi, Samir
Publicado 2021

Serum-free culture alters the quantity and protein composition of neuroblastoma-derived extracellular vesicles

por Li, Jinghuan, Lee, Yi, Johansson, Henrik J., Mäger, Imre, Vader, Pieter, Nordin, Joel Z., Wiklander, Oscar P. B., Lehtiö, Janne, Wood, Matthew J. A., Andaloussi, Samir EL
Publicado 2015

Lipidomic Analyses Reveal Specific Alterations of Phosphatidylcholine in Dystrophic Mdx Muscle

por Valentine, William J., Mostafa, Sherif A., Tokuoka, Suzumi M., Hamano, Fumie, Inagaki, Natsuko F., Nordin, Joel Z., Motohashi, Norio, Kita, Yoshihiro, Aoki, Yoshitsugu, Shimizu, Takao, Shindou, Hideo
Publicado 2022

Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice

por Cooper, J Mark, Wiklander, PB Oscar, Nordin, Joel Z, Al-Shawi, Raya, Wood, Matthew J, Vithlani, Mansi, Schapira, Anthony H V, Simons, J Paul, El-Andaloussi, Samir, Alvarez-Erviti, Lydia
Publicado 2014

Micro-minicircle Gene Therapy: Implications of Size on Fermentation, Complexation, Shearing Resistance, and Expression

por Stenler, Sofia, Wiklander, Oscar PB, Badal-Tejedor, Maria, Turunen, Janne, Nordin, Joel Z, Hallengärd, David, Wahren, Britta, Andaloussi, Samir EL, Rutland, Mark W, Smith, CI Edvard, Lundin, Karin E, Blomberg, Pontus
Publicado 2014

Profiling of Extracellular Small RNAs Highlights a Strong Bias towards Non-Vesicular Secretion

por Sork, Helena, Conceicao, Mariana, Corso, Giulia, Nordin, Joel, Lee, Yi Xin Fiona, Krjutskov, Kaarel, Orzechowski Westholm, Jakub, Vader, Pieter, Pauwels, Marie, Vandenbroucke, Roosmarijn E., Wood, Matthew JA, EL Andaloussi, Samir, Mäger, Imre
Publicado 2021

Systematic characterization of extracellular vesicle sorting domains and quantification at the single molecule – single vesicle level by fluorescence correlation spectroscopy and s...

por Corso, Giulia, Heusermann, Wolf, Trojer, Dominic, Görgens, André, Steib, Emmanuelle, Voshol, Johannes, Graff, Alexandra, Genoud, Christel, Lee, Yi, Hean, Justin, Nordin, Joel Z., Wiklander, Oscar P.B., El Andaloussi, Samir, Meisner-Kober, Nicole
Publicado 2019

Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome

por Sork, Helena, Corso, Giulia, Krjutskov, Kaarel, Johansson, Henrik J., Nordin, Joel Z., Wiklander, Oscar P. B., Lee, Yi Xin Fiona, Westholm, Jakub Orzechowski, Lehtiö, Janne, Wood, Matthew J. A., Mäger, Imre, EL Andaloussi, Samir
Publicado 2018

Identification of scaffold proteins for improved endogenous engineering of extracellular vesicles

por Zheng, Wenyi, Rädler, Julia, Sork, Helena, Niu, Zheyu, Roudi, Samantha, Bost, Jeremy P., Görgens, André, Zhao, Ying, Mamand, Doste R., Liang, Xiuming, Wiklander, Oscar P. B., Lehto, Taavi, Gupta, Dhanu, Nordin, Joel Z., EL Andaloussi, Samir
Publicado 2023

Correlating In Vitro Splice Switching Activity With Systemic In Vivo Delivery Using Novel ZEN-modified Oligonucleotides

por Hammond, Suzan M, McClorey, Graham, Nordin, Joel Z, Godfrey, Caroline, Stenler, Sofia, Lennox, Kim A, Smith, CI Edvard, Jacobi, Ashley M, Varela, Miguel A, Lee, Yi, Behlke, Mark A, Wood, Matthew J A, Andaloussi, Samir E L
Publicado 2014

Fine Tuning of Phosphorothioate Inclusion in 2′-O-Methyl Oligonucleotides Contributes to Specific Cell Targeting for Splice-Switching Modulation

por Aoki, Yoshitsugu, Rocha, Cristina S. J., Lehto, Taavi, Miyatake, Shouta, Johansson, Henrik, Hashimoto, Yasumasa, Nordin, Joel Z., Mager, Imre, Aoki, Misako, Graham, McClorey, Sathyaprakash, Chaitra, Roberts, Thomas C., Wood, Matthew J. A., Behlke, Mark A., Andaloussi, Samir El
Publicado 2021

Extracellular vesicles engineered to bind albumin demonstrate extended circulation time and lymph node accumulation in mouse models

por Liang, Xiuming, Niu, Zheyu, Galli, Valentina, Howe, Nathalie, Zhao, Ying, Wiklander, Oscar P. B., Zheng, Wenyi, Wiklander, Rim Jawad, Corso, Giulia, Davies, Christopher, Hean, Justin, Kyriakopoulou, Eleni, Mamand, Doste R., Amin, Risul, Nordin, Joel Z., Gupta, Dhanu, Andaloussi, Samir EL
Publicado 2022

Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency

por Sork, Helena, Nordin, Joel Z, Turunen, Janne J, Wiklander, Oscar PB, Bestas, Burcu, Zaghloul, Eman M, Margus, Helerin, Padari, Kärt, Duru, Adil D, Corso, Giulia, Bost, Jeremy, Vader, Pieter, Pooga, Margus, Smith, CI Edvard, Wood, Matthew JA, Schiffelers, Raymond M, Hällbrink, Mattias, Andaloussi, Samir EL
Publicado 2016

Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting

por Wiklander, Oscar P. B., Nordin, Joel Z., O’Loughlin, Aisling, Gustafsson, Ylva, Corso, Giulia, Mäger, Imre, Vader, Pieter, Lee, Yi, Sork, Helena, Seow, Yiqi, Heldring, Nina, Alvarez-Erviti, Lydia, Smith, CI Edvard, Le Blanc, Katarina, Macchiarini, Paolo, Jungebluth, Philipp, Wood, Matthew J. A., Andaloussi, Samir EL
Publicado 2015

Quantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imaging

por Gupta, Dhanu, Liang, Xiuming, Pavlova, Svetlana, Wiklander, Oscar P.B, Corso, Giulia, Zhao, Ying, Saher, Osama, Bost, Jeremy, Zickler, Antje M., Piffko, Andras, Maire, Cecile L., Ricklefs, Franz L., Gustafsson, Oskar, Llorente, Virginia Castilla, Gustafsson, Manuela O., Bostancioglu, R. Beklem, Mamand, Doste R, Hagey, Daniel W., Görgens, André, Nordin, Joel Z., EL Andaloussi, Samir
Publicado 2020

Systematic Methodological Evaluation of a Multiplex Bead-Based Flow Cytometry Assay for Detection of Extracellular Vesicle Surface Signatures

por Wiklander, Oscar P. B., Bostancioglu, R. Beklem, Welsh, Joshua A., Zickler, Antje M., Murke, Florian, Corso, Giulia, Felldin, Ulrika, Hagey, Daniel W., Evertsson, Björn, Liang, Xiu-Ming, Gustafsson, Manuela O., Mohammad, Dara K., Wiek, Constanze, Hanenberg, Helmut, Bremer, Michel, Gupta, Dhanu, Björnstedt, Mikael, Giebel, Bernd, Nordin, Joel Z., Jones, Jennifer C., EL Andaloussi, Samir, Görgens, André
Publicado 2018

In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome

por Simonson, Oscar E., Mougiakakos, Dimitrios, Heldring, Nina, Bassi, Giulio, Johansson, Henrik J., Dalén, Magnus, Jitschin, Regina, Rodin, Sergey, Corbascio, Matthias, El Andaloussi, Samir, Wiklander, Oscar P.B., Nordin, Joel Z., Skog, Johan, Romain, Charlotte, Koestler, Tina, Hellgren-Johansson, Laila, Schiller, Petter, Joachimsson, Per-Olof, Hägglund, Hans, Mattsson, Mattias, Lehtiö, Janne, Faridani, Omid R., Sandberg, Rickard, Korsgren, Olle, Krampera, Mauro, Weiss, Daniel J., Grinnemo, Karl-Henrik, Le Blanc, Katarina
Publicado 2016