Optimisation of Over-Expression in E. coli and Biophysical Characterisation of Human Membrane Protein Synaptogyrin 1

por Löw, Christian, Jegerschöld, Caroline, Kovermann, Michael, Moberg, Per, Nordlund, Pär
Publicado 2012

Functional Properties and Molecular Architecture of Leukotriene A4 Hydrolase, a Pivotal Catalyst of Chemotactic Leukotriene Formation

por Haeggström, Jesper Z., Nordlund, Pär, Thunnissen, Marjolein M.G.M.
Publicado 2002

VP22 core domain from Herpes simplex virus 1 reveals a surprising structural conservation in both the Alpha- and Gammaherpesvirinae subfamilies

por Hew, Kelly, Dahlroth, Sue-Li, Pan, Lucy Xin, Cornvik, Tobias, Nordlund, Pär
Publicado 2015

Structural and Biophysical Characterization of the Cytoplasmic Domains of Human BAP29 and BAP31

por Quistgaard, Esben M., Löw, Christian, Moberg, Per, Guettou, Fatma, Maddi, Karthik, Nordlund, Pär
Publicado 2013

Structural and Biochemical Characterization of Human PR70 in Isolation and in Complex with the Scaffolding Subunit of Protein Phosphatase 2A

por Dovega, Rebecca, Tsutakawa, Susan, Quistgaard, Esben M., Anandapadamanaban, Madhanagopal, Löw, Christian, Nordlund, Pär
Publicado 2014

Structure of the Varicella Zoster Virus Thymidylate Synthase Establishes Functional and Structural Similarities as the Human Enzyme and Potentiates Itself as a Target of Brivudine

por Hew, Kelly, Dahlroth, Sue-Li, Veerappan, Saranya, Pan, Lucy Xin, Cornvik, Tobias, Nordlund, Pär
Publicado 2015

Crystal Structures of Type-II Inositol Polyphosphate 5-Phosphatase INPP5B with Synthetic Inositol Polyphosphate Surrogates Reveal New Mechanistic Insights for the Inositol 5-Phosph...

por Mills, Stephen J., Silvander, Camilla, Cozier, Gyles, Trésaugues, Lionel, Nordlund, Pär, Potter, Barry V. L.
Publicado 2016

Pan-Pathway Based Interaction Profiling of FDA-Approved Nucleoside and Nucleobase Analogs with Enzymes of the Human Nucleotide Metabolism

por Egeblad, Louise, Welin, Martin, Flodin, Susanne, Gräslund, Susanne, Wang, Liya, Balzarini, Jan, Eriksson, Staffan, Nordlund, Pär
Publicado 2012

The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor

por Hew, Kelly, Dahlroth, Sue-Li, Venkatachalam, Rajakannan, Nasertorabi, Fariborz, Lim, Bee Ting, Cornvik, Tobias, Nordlund, Pär
Publicado 2013

Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate

por Trésaugues, Lionel, Lundbäck, Thomas, Welin, Martin, Flodin, Susanne, Nyman, Tomas, Silvander, Camilla, Gräslund, Susanne, Nordlund, Pär
Publicado 2015

Molecular insights into substrate recognition and catalytic mechanism of the chaperone and FKBP peptidyl-prolyl isomerase SlyD

por Quistgaard, Esben M., Weininger, Ulrich, Ural-Blimke, Yonca, Modig, Kristofer, Nordlund, Pär, Akke, Mikael, Löw, Christian
Publicado 2016

Quantitation of ERK1/2 inhibitor cellular target occupancies with a reversible slow off-rate probe

por Lebraud, Honorine, Surova, Olga, Courtin, Aurélie, O'Reilly, Marc, Valenzano, Chiara R., Nordlund, Pär, Heightman, Tom D.
Publicado 2018

The Crystal Structure of the Dachshund Domain of Human SnoN Reveals Flexibility in the Putative Protein Interaction Surface

por Nyman, Tomas, Trésaugues, Lionel, Welin, Martin, Lehtiö, Lari, Flodin, Susanne, Persson, Camilla, Johansson, Ida, Hammarström, Martin, Nordlund, Pär
Publicado 2010

HF-EPR, Raman, UV/VIS Light Spectroscopic, and DFT Studies of the Ribonucleotide Reductase R2 Tyrosyl Radical from Epstein-Barr Virus

por Tomter, Ane B., Zoppellaro, Giorgio, Schmitzberger, Florian, Andersen, Niels H., Barra, Anne-Laure, Engman, Henrik, Nordlund, Pär, Andersson, K. Kristoffer
Publicado 2011

Structural studies of tri-functional human GART

por Welin, Martin, Grossmann, Jörg Günter, Flodin, Susanne, Nyman, Tomas, Stenmark, Pål, Trésaugues, Lionel, Kotenyova, Tetyana, Johansson, Ida, Nordlund, Pär, Lehtiö, Lari
Publicado 2010

Arginine 104 Is a Key Catalytic Residue in Leukotriene C(4) Synthase

por Rinaldo-Matthis, Agnes, Wetterholm, Anders, Molina, Daniel Martinez, Holm, Johanna, Niegowski, Damian, Ohlson, Eva, Nordlund, Pär, Morgenstern, Ralf, Haeggström, Jesper Z.
Publicado 2010

Structure of the C‐terminal domain of nsp4 from feline coronavirus

por Manolaridis, Ioannis, Wojdyla, Justyna A., Panjikar, Santosh, Snijder, Eric J., Gorbalenya, Alexander E., Berglind, Hanna, Nordlund, Pär, Coutard, Bruno, Tucker, Paul A.
Publicado 2009

A Synthetic Polyphosphoinositide Headgroup Surrogate in Complex with SHIP2 Provides a Rationale for Drug Discovery

por Mills, Stephen J., Persson, Camilla, Cozier, Gyles, Thomas, Mark P., Trésaugues, Lionel, Erneux, Christophe, Riley, Andrew M., Nordlund, Pär, Potter, Barry V. L.
Publicado 2012

Nanobody Mediated Crystallization of an Archeal Mechanosensitive Channel

por Löw, Christian, Yau, Yin Hoe, Pardon, Els, Jegerschöld, Caroline, Wåhlin, Lisa, Quistgaard, Esben M., Moberg, Per, Geifman-Shochat, Susana, Steyaert, Jan, Nordlund, Pär
Publicado 2013

CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil

por Almqvist, Helena, Axelsson, Hanna, Jafari, Rozbeh, Dan, Chen, Mateus, André, Haraldsson, Martin, Larsson, Andreas, Molina, Daniel Martinez, Artursson, Per, Lundbäck, Thomas, Nordlund, Pär
Publicado 2016