Memory and Modularity in Cell-Fate Decision Making

por Norman, Thomas M., Lord, Nathan D., Paulsson, Johan, Losick, Richard
Publicado 2013

Environmental challenge rewires functional connections among human genes

por Herken, Benjamin W., Wong, Garrett T., Norman, Thomas M., Gilbert, Luke A.
Publicado 2023

Drivers of heterogeneity in synovial fibroblasts in rheumatoid arthritis

por Smith, Melanie H., Gao, Vianne R., Periyakoil, Preethi K., Kochen, Alejandro, DiCarlo, Edward F., Goodman, Susan M., Norman, Thomas M., Donlin, Laura T., Leslie, Christina S., Rudensky, Alexander Y.
Publicado 2023

Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs

por Jost, Marco, Santos, Daniel A., Saunders, Reuben A., Horlbeck, Max A., Hawkins, John S., Scaria, Sonia M., Norman, Thomas M., Hussmann, Jeffrey A., Liem, Christina R., Gross, Carol A., Weissman, Jonathan S.
Publicado 2020

Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq

por Replogle, Joseph M., Saunders, Reuben A., Pogson, Angela N., Hussmann, Jeffrey A., Lenail, Alexander, Guna, Alina, Mascibroda, Lauren, Wagner, Eric J., Adelman, Karen, Lithwick-Yanai, Gila, Iremadze, Nika, Oberstrass, Florian, Lipson, Doron, Bonnar, Jessica L., Jost, Marco, Norman, Thomas M., Weissman, Jonathan S.
Publicado 2022

Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing

por Replogle, Joseph M., Norman, Thomas M., Xu, Albert, Hussmann, Jeffrey A., Chen, Jin, Cogan, J. Zachary, Meer, Elliott J., Terry, Jessica M., Riordan, Daniel P., Srinivas, Niranjan, Fiddes, Ian T., Arthur, Joseph G., Alvarado, Luigi J., Pfeiffer, Katherine A., Mikkelsen, Tarjei S., Weissman, Jonathan S., Adamson, Britt
Publicado 2020

Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors

por Replogle, Joseph M, Bonnar, Jessica L, Pogson, Angela N, Liem, Christina R, Maier, Nolan K, Ding, Yufang, Russell, Baylee J, Wang, Xingren, Leng, Kun, Guna, Alina, Norman, Thomas M, Pak, Ryan A, Ramos, Daniel M, Ward, Michael E, Gilbert, Luke A, Kampmann, Martin, Weissman, Jonathan S, Jost, Marco
Publicado 2022