Discovery of a Selective, Substrate-Competitive Inhibitor of the Lysine Methyltransferase SETD8

por Ma, Anqi, Yu, Wenyu, Li, Fengling, Bleich, Rachel M., Herold, J. Martin, Butler, Kyle V., Norris, Jacqueline L., Korboukh, Victoria, Tripathy, Ashutosh, Janzen, William P., Arrowsmith, Cheryl H., Frye, Stephen V., Vedadi, Masoud, Brown, Peter J., Jin, Jian
Publicado 2014

Expression of Ror2 Mediates Invasive Phenotypes in Renal Cell Carcinoma

por Rasmussen, Neal R., Debebe, Zufan, Wright, Tricia M., Brooks, Samira A., Sendor, Adam B., Brannon, A . Rose, Hakimi, A . Ari, Hsieh, James J., Choueiri, Toni K., Tamboli, Pheroze, Maranchie, Jodi K., Hinds, Peter, Wallen, Eric M., Simpson, Catherine, Norris, Jacqueline L., Janzen, William P., Rathmell, W. Kimryn
Publicado 2014

Discovery of a chemical probe for the L3MBTL3 methyl-lysine reader domain

por James, Lindsey I., Barsyte-Lovejoy, Dalia, Zhong, Nan, Krichevsky, Liubov, Korboukh, Victoria K., Herold, Martin J., MacNevin, Christopher J., Norris, Jacqueline L., Sagum, Cari A., Tempel, Wolfram, Marcon, Edyta, Guo, Hongbo, Gao, Cen, Huang, Xi-Ping, Duan, Shili, Emili, Andrew, Greenblatt, Jack F., Kireev, Dmitri B., Jin, Jian, Janzen, William P., Brown, Peter J., Bedford, Mark T., Arrowsmith, Cheryl H., Frye, Stephen V.
Publicado 2013

A cellular chemical probe targeting the chromodomains of Polycomb Repressive Complex 1

por Stuckey, Jacob I, Dickson, Bradley M, Cheng, Nancy, Liu, Yanli, Norris, Jacqueline L, Cholensky, Stephanie H, Tempel, Wolfram, Qin, Su, Huber, Katherine G, Sagum, Cari, Black, Karynne, Li, Fengling, Huang, Xi-Ping, Roth, Bryan L, Baughman, Brandi M, Senisterra, Guillermo, Pattenden, Samantha G, Vedadi, Masoud, Brown, Peter J, Bedford, Mark T, Min, Jinrong, Arrowsmith, Cheryl H, James, Lindsey I, Frye, Stephen V
Publicado 2016

Reprogramming CBX8-PRC1 function with a positive allosteric modulator

por Suh, Junghyun L., Bsteh, Daniel, Hart, Bryce, Si, Yibo, Weaver, Tyler M., Pribitzer, Carina, Lau, Roy, Soni, Shivani, Ogana, Heather, Rectenwald, Justin M., Norris, Jacqueline L., Cholensky, Stephanie H., Sagum, Cari, Umana, Jessica D., Li, Dongxu, Hardy, Brian, Bedford, Mark T., Mumenthaler, Shannon M., Lenz, Heinz-Josef, Kim, Yong-Mi, Wang, Gang Greg, Pearce, Ken H., James, Lindsey I., Kireev, Dmitri B., Musselman, Catherine A., Frye, Stephen V., Bell, Oliver
Publicado 2022