MDB-28. DEEP LEARNING-BASED PERSONALIZED SURVIVAL PREDICTION FOR MEDULLOBLASTOMA

por Stefan, Sabina, Northcott, Paul, Hovestadt, Volker
Publicado 2023

Mouse models of medulloblastoma

por Wu, Xiaochong, Northcott, Paul A., Croul, Sidney, Taylor, Michael D.
Publicado 2011

Nexilin, a Cardiomyopathy-Associated F-Actin Binding Protein, Binds and Regulates IRS1 Signaling in Skeletal Muscle Cells

por Lee, Andrew, Hakuno, Fumihiko, Northcott, Paul, Pessin, Jeffrey E., Adcock, Maria Rozakis
Publicado 2013

Low-coverage whole-genome sequencing of cerebrospinal-fluid-derived cell-free DNA in brain tumor patients

por Liu, Anthony P.Y., Smith, Kyle S., Kumar, Rahul, Robinson, Giles W., Northcott, Paul A.
Publicado 2022

Depletion of kinesin motor KIF20A to target cell fate control suppresses medulloblastoma tumour growth

por Qiu, Runxiang, Wu, Jun, Gudenas, Brian, Northcott, Paul A., Wechsler-Reya, Robert J., Lu, Qiang
Publicado 2021

MEDB-82. Exploring cell-cell communication networks in medulloblastoma using single-cell genomics

por Gabler, Lisa, Gojo, Johannes, Smith, Kyle S, Bihannic, Laure, Filbin, Mariella G, Northcott, Paul A, Berger, Walter, Hovestadt, Volker
Publicado 2022

Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation

por Fernandez-L, Africa, Squatrito, Massimo, Northcott, Paul, Awan, Aashir, Holland, Eric C., Taylor, Michael D., Nahlé, Zaher, Kenney, Anna Marie
Publicado 2011

Lmx1a is a master regulator of the cortical hem

por Iskusnykh, Igor Y, Fattakhov, Nikolai, Li, Yiran, Bihannic, Laure, Kirchner, Matthew K, Steshina, Ekaterina Y, Northcott, Paul A, Chizhikov, Victor V
Publicado 2023

INSP-09. Using genetically engineered mouse models and patient-derived orthotopic xenografts to develop new therapies for pediatric brain tumors.

por Jonchere, Barbara, Pribnow, Allison, Morfouace, Marie, Shelat, Anang, Yu, Jiyang, Rankovic, Zoran, Gajjar, Amar, Northcott, Paul A, Robinson, Giles W, Roussel, Martine F
Publicado 2022

A genetic mouse model with postnatal Nf1 and p53 loss recapitulates the histology and transcriptome of human malignant peripheral nerve sheath tumor

por Inoue, Akira, Janke, Laura J, Gudenas, Brian L, Jin, Hongjian, Fan, Yiping, Paré, Joshua, Clay, Michael R, Northcott, Paul A, Hirbe, Angela C, Cao, Xinwei
Publicado 2021

MDB-29. MEDULLOBLASTOMA SUBGROUP-SPECIFIC CHROMATIN STATES REVEAL NOVEL THERAPEUTIC VULNERABILITIES

por Tao, Ran, Gao, Qingsong, Erkek, Serap, Matsui, Yurika, Djekidel, Nadhir, Darrow, Emily, Kumar, Rahul, Smith, Kyle, Wu, Gang, Korbel, Jan, Peng, Jamy, Pfister, Stefan, Northcott, Paul
Publicado 2023

The WIP1 Oncogene Promotes Progression and Invasion of Aggressive Medulloblastoma Variants

por Buss, Meghan C., Remke, Marc, Lee, Juhyun, Gandhi, Khanjan, Schniederjan, Matthew J., Kool, Marcel, Northcott, Paul A., Pfister, Stefan M., Taylor, Michael D., Castellino, Robert C.
Publicado 2014

Coverage Bias and Sensitivity of Variant Calling for Four Whole-genome Sequencing Technologies

por Rieber, Nora, Zapatka, Marc, Lasitschka, Bärbel, Jones, David, Northcott, Paul, Hutter, Barbara, Jäger, Natalie, Kool, Marcel, Taylor, Michael, Lichter, Peter, Pfister, Stefan, Wolf, Stephan, Brors, Benedikt, Eils, Roland
Publicado 2013

MBCL-15. IMPACT OF MOLECULAR SUBGROUPS ON OUTCOMES FOLLOWING RADIATION TREATMENT RANDOMIZATIONS FOR AVERAGE RISK MEDULLOBLASTOMA: A PLANNED ANALYSIS OF CHILDREN’S ONCOLOGY GROUP (C...

por Michalski, Jeff, Northcott, Paul, Li, Yimei, Billups, Catherine, Smith, Kyle, Burger, Peter, Merchant, Thomas, Gajjar, Amar, Fitzgerald, T J, Vezina, Gilbert, Fouladi, Maryam, Packer, Roger, Tarbell, Nancy, Janss, Anna
Publicado 2020

MBRS-24. FUNCTIONAL CHARACTERIZATION OF IKBKAP/ELP1 AS A NOVEL SHH MEDULLOBLASTOMA PREDISPOSITION GENE

por Lopez, Jesus Garcia, Kutscher, Lena, Kojic, Marija, Gudenas, Brian, Smith, Kyle, Hadley, Jennifer, Gajjar, Amar, Robinson, Giles W, Pfister, Stefan M, Wainwright, Brandon J, Kawauchi, Daisuke, Northcott, Paul A
Publicado 2020

Large 1p36 Deletions Affecting Arid1a Locus Facilitate Mycn-Driven Oncogenesis in Neuroblastoma

por García-López, Jesus, Wallace, Kirby, Otero, Joel H., Olsen, Rachelle, Wang, Yong-dong, Finkelstein, David, Gudenas, Brian L., Rehg, Jerold E., Northcott, Paul, Davidoff, Andrew M., Freeman, Kevin W.
Publicado 2020

BIOL-23. LOSS OF MICRORNAS COOPERATES WITH TUMOR SUPPRESSORS TO INITIATE MYC-DEPENDENT METASTATIC MEDULLOBLASTOMA

por Llaguno, Sheila Alcantara, Nazarenko, Inga, Chen, Yuntao, Sun, Daochun, Gudenas, Brian, Saulnier, Olivier, Rocca, Gaspare La, Pedraza, Alicia, Burns, Dennis, Bale, Tejus, Ventura, Andrea, Northcott, Paul, Taylor, Michael, Parada, Luis
Publicado 2023

Proteomic analysis of Medulloblastoma reveals functional biology with translational potential

por Rivero-Hinojosa, Samuel, Lau, Ling San, Stampar, Mojca, Staal, Jerome, Zhang, Huizhen, Gordish-Dressman, Heather, Northcott, Paul A., Pfister, Stefan M., Taylor, Michael D., Brown, Kristy J., Rood, Brian R.
Publicado 2018

MBCL-16. EFFICACY OF CARBOPLATIN GIVEN CONCOMITANTLY WITH RADIATION AND ISOTRETINOIN AS A PRO-APOPTOTIC AGENT IN MAINTENANCE THERAPY IN HIGH-RISK MEDULLOBLASTOMA: A REPORT FROM THE...

por Leary, Sarah, Packer, Roger, Jaju, Alok, Heier, Linda, Burger, Peter, Smith, Kyle, Michalski, Jeff, Li, Yimei, Billups, Catherine, Hwang, Eugene, Gajjar, Amar, Pollack, Ian, Fouladi, Maryam, Northcott, Paul, Olson, James
Publicado 2020

TMOD-06. LOSS OF DICER COOPERATES WITH TUMOR SUPPRESSORS TO INITIATE METASTATIC MEDULLOBLASTOMA

por Alcantara Llaguno, Sheila, Nazarenko, Inga, Chen, Yuntao, Sun, Daochun, Rocca, Gaspare La, Pedraza, Alicia, Gudenas, Brian, Saulnier, Olivier, Burns, Dennis, Bale, Tejus, Northcott, Paul, Taylor, Michael, Ventura, Andrea, Parada, Luis
Publicado 2021