Shear stress control of vascular leaks and atheromas through Tie2 activation by VE‐PTP sequestration

por Shirakura, Keisuke, Baluk, Peter, Nottebaum, Astrid F, Ipe, Ute, Peters, Kevin G, McDonald, Donald M, Vestweber, Dietmar
Publicado 2023

VE-PTP controls blood vessel development by balancing Tie-2 activity

por Winderlich, Mark, Keller, Linda, Cagna, Giuseppe, Broermann, Andre, Kamenyeva, Olena, Kiefer, Friedemann, Deutsch, Urban, Nottebaum, Astrid F., Vestweber, Dietmar
Publicado 2009

Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo

por Broermann, Andre, Winderlich, Mark, Block, Helena, Frye, Maike, Rossaint, Jan, Zarbock, Alexander, Cagna, Giuseppe, Linnepe, Ruth, Schulte, Dörte, Nottebaum, Astrid Fee, Vestweber, Dietmar
Publicado 2011

Extracellular Vesicle Transfer from Endothelial Cells Drives VE-Cadherin Expression in Breast Cancer Cells, Thereby Causing Heterotypic Cell Contacts

por Rezaei, Maryam, Martins Cavaco, Ana C., Stehling, Martin, Nottebaum, Astrid, Brockhaus, Katrin, Caliandro, Michele F., Schelhaas, Sonja, Schmalbein, Felix, Vestweber, Dietmar, Eble, Johannes A.
Publicado 2020

Interfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin

por Frye, Maike, Dierkes, Martina, Küppers, Verena, Vockel, Matthias, Tomm, Janina, Zeuschner, Dagmar, Rossaint, Jan, Zarbock, Alexander, Koh, Gou Young, Peters, Kevin, Nottebaum, Astrid Fee, Vestweber, Dietmar
Publicado 2015

VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF

por Nottebaum, Astrid F., Cagna, Giuseppe, Winderlich, Mark, Gamp, Alexander C., Linnepe, Ruth, Polaschegg, Christian, Filippova, Kristina, Lyck, Ruth, Engelhardt, Britta, Kamenyeva, Olena, Bixel, Maria Gabriele, Butz, Stefan, Vestweber, Dietmar
Publicado 2008

Local microvascular leakage promotes trafficking of activated neutrophils to remote organs

por Owen-Woods, Charlotte, Joulia, Régis, Barkaway, Anna, Rolas, Loïc, Ma, Bin, Nottebaum, Astrid Fee, Arkill, Kenton P., Stein, Monja, Girbl, Tamara, Golding, Matthew, Bates, David O., Vestweber, Dietmar, Voisin, Mathieu-Benoit, Nourshargh, Sussan
Publicado 2020

A Small Molecule Inhibitor of VE-PTP Activates Tie2 in Schlemm's Canal Increasing Outflow Facility and Reducing Intraocular Pressure

por Li, Guorong, Nottebaum, Astrid F., Brigell, Mitchell, Navarro, Iris D., Ipe, Ute, Mishra, Sarthak, Gomez-Caraballo, Maria, Schmitt, Heather, Soldo, Brandi, Pakola, Steve, Withers, Barbara, Peters, Kevin G., Vestweber, Dietmar, Stamer, W. Daniel
Publicado 2020

Force-induced changes of α-catenin conformation stabilize vascular junctions independently of vinculin

por Duong, Cao Nguyen, Brückner, Randy, Schmitt, Martina, Nottebaum, Astrid F., Braun, Laura J., Meyer zu Brickwedde, Marika, Ipe, Ute, vom Bruch, Hermann, Schöler, Hans R., Trapani, Giuseppe, Trappmann, Britta, Ebrahimkutty, Mirsana P., Huveneers, Stephan, de Rooij, Johan, Ishiyama, Noboru, Ikura, Mitsuhiko, Vestweber, Dietmar
Publicado 2021