Shear stress control of vascular leaks and atheromas through Tie2 activation by VE‐PTP sequestration

por Shirakura, Keisuke, Baluk, Peter, Nottebaum, Astrid F, Ipe, Ute, Peters, Kevin G, McDonald, Donald M, Vestweber, Dietmar
Publicado 2023

VE-PTP controls blood vessel development by balancing Tie-2 activity

por Winderlich, Mark, Keller, Linda, Cagna, Giuseppe, Broermann, Andre, Kamenyeva, Olena, Kiefer, Friedemann, Deutsch, Urban, Nottebaum, Astrid F., Vestweber, Dietmar
Publicado 2009

VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF

por Nottebaum, Astrid F., Cagna, Giuseppe, Winderlich, Mark, Gamp, Alexander C., Linnepe, Ruth, Polaschegg, Christian, Filippova, Kristina, Lyck, Ruth, Engelhardt, Britta, Kamenyeva, Olena, Bixel, Maria Gabriele, Butz, Stefan, Vestweber, Dietmar
Publicado 2008

A Small Molecule Inhibitor of VE-PTP Activates Tie2 in Schlemm's Canal Increasing Outflow Facility and Reducing Intraocular Pressure

por Li, Guorong, Nottebaum, Astrid F., Brigell, Mitchell, Navarro, Iris D., Ipe, Ute, Mishra, Sarthak, Gomez-Caraballo, Maria, Schmitt, Heather, Soldo, Brandi, Pakola, Steve, Withers, Barbara, Peters, Kevin G., Vestweber, Dietmar, Stamer, W. Daniel
Publicado 2020

Force-induced changes of α-catenin conformation stabilize vascular junctions independently of vinculin

por Duong, Cao Nguyen, Brückner, Randy, Schmitt, Martina, Nottebaum, Astrid F., Braun, Laura J., Meyer zu Brickwedde, Marika, Ipe, Ute, vom Bruch, Hermann, Schöler, Hans R., Trapani, Giuseppe, Trappmann, Britta, Ebrahimkutty, Mirsana P., Huveneers, Stephan, de Rooij, Johan, Ishiyama, Noboru, Ikura, Mitsuhiko, Vestweber, Dietmar
Publicado 2021