Reverse Translation in Tuberculosis: Neutrophils Provide Clues for Understanding Development of Active Disease

por Dorhoi, Anca, Iannaccone, Marco, Maertzdorf, Jeroen, Nouailles, Geraldine, Weiner, January, Kaufmann, Stefan H. E.
Publicado 2014

Soluble mucus component CLCA1 modulates expression of leukotactic cytokines and BPIFA1 in murine alveolar macrophages but not in bone marrow-derived macrophages

por Erickson, Nancy A., Dietert, Kristina, Enders, Jana, Glauben, Rainer, Nouailles, Geraldine, Gruber, Achim D., Mundhenk, Lars
Publicado 2018

A biomathematical model of atherosclerosis in mice

por Schirm, Sibylle, Haghikia, Arash, Brack, Markus, Ahnert, Peter, Nouailles, Geraldine, Suttorp, Norbert, Loeffler, Markus, Witzenrath, Martin, Scholz, Markus
Publicado 2022

Protocol to dissociate healthy and infected murine- and hamster-derived lung tissue for single-cell transcriptome analysis

por Pennitz, Peter, Goekeri, Cengiz, Trimpert, Jakob, Wyler, Emanuel, Ebenig, Aileen, Weissfuss, Chantal, Mühlebach, Michael D., Witzenrath, Martin, Nouailles, Geraldine
Publicado 2022

On Top of the Alveolar Epithelium: Surfactant and the Glycocalyx

por Ochs, Matthias, Hegermann, Jan, Lopez-Rodriguez, Elena, Timm, Sara, Nouailles, Geraldine, Matuszak, Jasmin, Simmons, Szandor, Witzenrath, Martin, Kuebler, Wolfgang M.
Publicado 2020

A biomathematical model of immune response and barrier function in mice with pneumococcal lung infection

por Schirm, Sibylle, Ahnert, Peter, Berger, Sarah, Nouailles, Geraldine, Wienhold, Sandra-Maria, Müller-Redetzky, Holger, Suttorp, Norbert, Loeffler, Markus, Witzenrath, Martin, Scholz, Markus
Publicado 2020

De Novo-Whole Genome Assembly of the Roborovski Dwarf Hamster (Phodopus roborovskii) Genome: An Animal Model for Severe/Critical COVID-19

por Andreotti, Sandro, Altmüller, Janine, Quedenau, Claudia, Borodina, Tatiana, Nouailles, Geraldine, Teixeira Alves, Luiz Gustavo, Landthaler, Markus, Bieniara, Maximilian, Trimpert, Jakob, Wyler, Emanuel
Publicado 2022

Adjunctive therapy with the Tie2 agonist Vasculotide reduces pulmonary permeability in Streptococcus pneumoniae infected and mechanically ventilated mice

por Lask, Aina, Gutbier, Birgitt, Kershaw, Olivia, Nouailles, Geraldine, Gruber, Achim D., Müller-Redetzky, Holger C., Chackowicz, Steven, Hamilton, Douglas A., Van Slyke, Paul, Witzenrath, Martin
Publicado 2022

Delay in antibiotic therapy results in fatal disease outcome in murine pneumococcal pneumonia

por Berger, Sarah, Goekeri, Cengiz, Gupta, Shishir K., Vera, Julio, Dietert, Kristina, Behrendt, Ulrike, Lienau, Jasmin, Wienhold, Sandra-Maria, Gruber, Achim D., Suttorp, Norbert, Witzenrath, Martin, Nouailles, Geraldine
Publicado 2018

Humanized Mouse Model Mimicking Pathology of Human Tuberculosis for in vivo Evaluation of Drug Regimens

por Arrey, Frida, Löwe, Delia, Kuhlmann, Stefanie, Kaiser, Peggy, Moura-Alves, Pedro, Krishnamoorthy, Gopinath, Lozza, Laura, Maertzdorf, Jeroen, Skrahina, Tatsiana, Skrahina, Alena, Gengenbacher, Martin, Nouailles, Geraldine, Kaufmann, Stefan H. E.
Publicado 2019

The unremarkable alveolar epithelial glycocalyx: a thorium dioxide-based electron microscopic comparison after heparinase or pneumolysin treatment

por Timm, Sara, Lettau, Marie, Hegermann, Jan, Rocha, Maria Linda, Weidenfeld, Sarah, Fatykhova, Diana, Gutbier, Birgitt, Nouailles, Geraldine, Lopez-Rodriguez, Elena, Hocke, Andreas, Hippenstiel, Stefan, Witzenrath, Martin, Kuebler, Wolfgang M., Ochs, Matthias
Publicado 2023

Type I IFN signaling triggers immunopathology in tuberculosis-susceptible mice by modulating lung phagocyte dynamics

por Dorhoi, Anca, Yeremeev, Vladimir, Nouailles, Geraldine, Weiner, January, Jörg, Sabine, Heinemann, Ellen, Oberbeck-Müller, Dagmar, Knaul, Julia K, Vogelzang, Alexis, Reece, Stephen T, Hahnke, Karin, Mollenkopf, Hans-Joachim, Brinkmann, Volker, Kaufmann, Stefan H E
Publicado 2014

Ventilator-induced lung injury is aggravated by antibiotic mediated microbiota depletion in mice

por Wienhold, Sandra-Maria, Macrì, Mario, Nouailles, Geraldine, Dietert, Kristina, Gurtner, Corinne, Gruber, Achim D, Heimesaat, Markus M, Lienau, Jasmin, Schumacher, Fabian, Kleuser, Burkhard, Opitz, Bastian, Suttorp, Norbert, Witzenrath, Martin, Müller-Redetzky, Holger C
Publicado 2018

Repetitive Exposure to Bacteriophage Cocktails against Pseudomonas aeruginosa or Escherichia coli Provokes Marginal Humoral Immunity in Naïve Mice

por Weissfuss, Chantal, Wienhold, Sandra-Maria, Bürkle, Magdalena, Gaborieau, Baptiste, Bushe, Judith, Behrendt, Ulrike, Bischoff, Romina, Korf, Imke H. E., Wienecke, Sarah, Dannheim, Antonia, Ziehr, Holger, Rohde, Christine, Gruber, Achim D., Ricard, Jean-Damien, Debarbieux, Laurent, Witzenrath, Martin, Nouailles, Geraldine
Publicado 2023

MicroRNA-223 Dampens Pulmonary Inflammation during Pneumococcal Pneumonia

por Goekeri, Cengiz, Pennitz, Peter, Groenewald, Wibke, Behrendt, Ulrike, Kirsten, Holger, Zobel, Christian M., Berger, Sarah, Heinz, Gitta A., Mashreghi, Mir-Farzin, Wienhold, Sandra-Maria, Dietert, Kristina, Dorhoi, Anca, Gruber, Achim D., Scholz, Markus, Rohde, Gernot, Suttorp, Norbert, Witzenrath, Martin, Nouailles, Geraldine
Publicado 2023

A pulmonologist's guide to perform and analyse cross-species single lung cell transcriptomics

por Pennitz, Peter, Kirsten, Holger, Friedrich, Vincent D., Wyler, Emanuel, Goekeri, Cengiz, Obermayer, Benedikt, Heinz, Gitta A., Mashreghi, Mir-Farzin, Büttner, Maren, Trimpert, Jakob, Landthaler, Markus, Suttorp, Norbert, Hocke, Andreas C., Hippenstiel, Stefan, Tönnies, Mario, Scholz, Markus, Kuebler, Wolfgang M., Witzenrath, Martin, Hoenzke, Katja, Nouailles, Geraldine
Publicado 2022

Preclinical Assessment of Bacteriophage Therapy against Experimental Acinetobacter baumannii Lung Infection

por Wienhold, Sandra-Maria, Brack, Markus C., Nouailles, Geraldine, Krishnamoorthy, Gopinath, Korf, Imke H. E., Seitz, Claudius, Wienecke, Sarah, Dietert, Kristina, Gurtner, Corinne, Kershaw, Olivia, Gruber, Achim D., Ross, Anton, Ziehr, Holger, Rohde, Manfred, Neudecker, Jens, Lienau, Jasmin, Suttorp, Norbert, Hippenstiel, Stefan, Hocke, Andreas C., Rohde, Christine, Witzenrath, Martin
Publicado 2021

Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19

por Nouailles, Geraldine, Wyler, Emanuel, Pennitz, Peter, Postmus, Dylan, Vladimirova, Daria, Kazmierski, Julia, Pott, Fabian, Dietert, Kristina, Muelleder, Michael, Farztdinov, Vadim, Obermayer, Benedikt, Wienhold, Sandra-Maria, Andreotti, Sandro, Hoefler, Thomas, Sawitzki, Birgit, Drosten, Christian, Sander, Leif E., Suttorp, Norbert, Ralser, Markus, Beule, Dieter, Gruber, Achim D., Goffinet, Christine, Landthaler, Markus, Trimpert, Jakob, Witzenrath, Martin
Publicado 2021

Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single-cell transcriptomics

por Wyler, Emanuel, Adler, Julia M., Eschke, Kathrin, Teixeira Alves, G., Peidli, Stefan, Pott, Fabian, Kazmierski, Julia, Michalick, Laura, Kershaw, Olivia, Bushe, Judith, Andreotti, Sandro, Pennitz, Peter, Abdelgawad, Azza, Postmus, Dylan, Goffinet, Christine, Kreye, Jakob, Reincke, S Momsen, Prüss, Harald, Blüthgen, Nils, Gruber, Achim D., Kuebler, Wolfgang M., Witzenrath, Martin, Landthaler, Markus, Nouailles, Geraldine, Trimpert, Jakob
Publicado 2022

Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after T(H)2-biased immunization

por Ebenig, Aileen, Muraleedharan, Samada, Kazmierski, Julia, Todt, Daniel, Auste, Arne, Anzaghe, Martina, Gömer, André, Postmus, Dylan, Gogesch, Patricia, Niles, Marc, Plesker, Roland, Miskey, Csaba, Gellhorn Serra, Michelle, Breithaupt, Angele, Hörner, Cindy, Kruip, Carina, Ehmann, Rosina, Ivics, Zoltan, Waibler, Zoe, Pfaender, Stephanie, Wyler, Emanuel, Landthaler, Markus, Kupke, Alexandra, Nouailles, Geraldine, Goffinet, Christine, Brown, Richard J.P., Mühlebach, Michael D.
Publicado 2022