Ten Years of Tau-Targeted Immunotherapy: The Path Walked and the Roads Ahead

por Novak, Petr, Kontsekova, Eva, Zilka, Norbert, Novak, Michal
Publicado 2018

First-in-man tau vaccine targeting structural determinants essential for pathological tau–tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheim...

por Kontsekova, Eva, Zilka, Norbert, Kovacech, Branislav, Novak, Petr, Novak, Michal
Publicado 2014

Identification of structural determinants on tau protein essential for its pathological function: novel therapeutic target for tau immunotherapy in Alzheimer’s disease

por Kontsekova, Eva, Zilka, Norbert, Kovacech, Branislav, Skrabana, Rostislav, Novak, Michal
Publicado 2014

Risk factors for canine cognitive dysfunction syndrome in Slovakia

por Katina, Stanislav, Farbakova, Jana, Madari, Aladar, Novak, Michal, Zilka, Norbert
Publicado 2016

Genetic background modifies neurodegeneration and neuroinflammation driven by misfolded human tau protein in rat model of tauopathy: implication for immunomodulatory approach to Al...

por Stozicka, Zuzana, Zilka, Norbert, Novak, Petr, Kovacech, Branislav, Bugos, Ondrej, Novak, Michal
Publicado 2010

Truncated tau deregulates synaptic markers in rat model for human tauopathy

por Jadhav, Santosh, Katina, Stanislav, Kovac, Andrej, Kazmerova, Zuzana, Novak, Michal, Zilka, Norbert
Publicado 2015

Novel mutations in TLR genes cause hyporesponsiveness to Mycobacterium avium subsp. paratuberculosis infection

por Bhide, Mangesh R, Mucha, Rastislav, Mikula, Ivan, Kisova, Lucia, Skrabana, Rostislav, Novak, Michal, Mikula, Ivan
Publicado 2009

The Distance between N and C Termini of Tau and of FTDP-17 Mutants Is Modulated by Microtubule Interactions in Living Cells

por Di Primio, Cristina, Quercioli, Valentina, Siano, Giacomo, Rovere, Matteo, Kovacech, Branislav, Novak, Michal, Cattaneo, Antonino
Publicado 2017

OspA-CD40 dyad: ligand-receptor interaction in the translocation of neuroinvasive Borrelia across the blood-brain barrier

por Pulzova, Lucia, Kovac, Andrej, Mucha, Rastislav, Mlynarcik, Patrik, Bencurova, Elena, Madar, Marian, Novak, Michal, Bhide, Mangesh
Publicado 2011

Who fans the flames of Alzheimer's disease brains? Misfolded tau on the crossroad of neurodegenerative and inflammatory pathways

por Zilka, Norbert, Kazmerova, Zuzana, Jadhav, Santosh, Neradil, Peter, Madari, Aladar, Obetkova, Dominika, Bugos, Ondrej, Novak, Michal
Publicado 2012

Microglia display modest phagocytic capacity for extracellular tau oligomers

por Majerova, Petra, Zilkova, Monika, Kazmerova, Zuzana, Kovac, Andrej, Paholikova, Kristina, Kovacech, Branislav, Zilka, Norbert, Novak, Michal
Publicado 2014

Tauopathy in transgenic (SHR72) rats impairs function of central noradrenergic system and promotes neuroinflammation

por Mravec, Boris, Lejavova, Katarina, Vargovic, Peter, Ondicova, Katarina, Horvathova, Lubica, Novak, Petr, Manz, Georg, Filipcik, Peter, Novak, Michal, Kvetnansky, Richard
Publicado 2016

Therapeutic antibody targeting microtubule-binding domain prevents neuronal internalization of extracellular tau via masking neuron surface proteoglycans

por Weisová, Petronela, Cehlár, Ondrej, Škrabana, Rostislav, Žilková, Monika, Filipčík, Peter, Kováčech, Branislav, Prčina, Michal, Wojčiaková, Ľubica, Fialová, Ľubica, Smolek, Tomáš, Kontseková, Eva, Žilka, Norbert, Novák, Michal
Publicado 2019

Humanized tau antibodies promote tau uptake by human microglia without any increase of inflammation

por Zilkova, Monika, Nolle, Anna, Kovacech, Branislav, Kontsekova, Eva, Weisova, Petronela, Filipcik, Peter, Skrabana, Rostislav, Prcina, Michal, Hromadka, Tomas, Cehlar, Ondrej, Rolkova, Gabriela Paulikova, Maderova, Denisa, Novak, Michal, Zilka, Norbert, Hoozemans, Jeroen J. M.
Publicado 2020

Evaluation of a novel immunoassay to detect p-tau Thr217 in the CSF to distinguish Alzheimer disease from other dementias

por Hanes, Jozef, Kovac, Andrej, Kvartsberg, Hlin, Kontsekova, Eva, Fialova, Lubica, Katina, Stanislav, Kovacech, Branislav, Stevens, Eva, Hort, Jakub, Vyhnalek, Martin, Boonkamp, Lynn, Novak, Michal, Zetterberg, Henrik, Hansson, Oskar, Scheltens, Philip, Blennow, Kaj, Teunissen, Charlotte E., Zilka, Norbert
Publicado 2020

FUNDAMANT: an interventional 72-week phase 1 follow-up study of AADvac1, an active immunotherapy against tau protein pathology in Alzheimer’s disease

por Novak, Petr, Schmidt, Reinhold, Kontsekova, Eva, Kovacech, Branislav, Smolek, Tomas, Katina, Stanislav, Fialova, Lubica, Prcina, Michal, Parrak, Vojtech, Dal-Bianco, Peter, Brunner, Martin, Staffen, Wolfgang, Rainer, Michael, Ondrus, Matej, Ropele, Stefan, Smisek, Miroslav, Sivak, Roman, Zilka, Norbert, Winblad, Bengt, Novak, Michal
Publicado 2018

Monoclonal antibodies targeting two immunodominant epitopes on the Spike protein neutralize emerging SARS-CoV-2 variants of concern

por Kovacech, Branislav, Fialova, Lubica, Filipcik, Peter, Skrabana, Rostislav, Zilkova, Monika, Paulenka-Ivanovova, Natalia, Kovac, Andrej, Palova, Denisa, Rolkova, Gabriela Paulikova, Tomkova, Katarina, Csokova, Natalia Turic, Markova, Karina, Skrabanova, Michaela, Sinska, Kristina, Basheer, Neha, Majerova, Petra, Hanes, Jozef, Parrak, Vojtech, Prcina, Michal, Cehlar, Ondrej, Cente, Martin, Piestansky, Juraj, Fresser, Michal, Novak, Michal, Slavikova, Monika, Borsova, Kristina, Cabanova, Viktoria, Brejova, Bronislava, Vinař, Tomas, Nosek, Jozef, Klempa, Boris, Eyer, Ludek, Hönig, Vaclav, Palus, Martin, Ruzek, Daniel, Vyhlidalova, Tereza, Strakova, Petra, Mrazkova, Blanka, Zudova, Dagmar, Koubkova, Gizela, Novosadova, Vendula, Prochazka, Jan, Sedlacek, Radislav, Zilka, Norbert, Kontsekova, Eva
Publicado 2022

Abstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers

por Małecki, Andrzej, Skipor-Lahuta, Janina, Toborek, Michal, Abbott, N. Joan, Antonetti, David A., Su, Enming Joe, Lawrence, Daniel A., Atış, Müge, Akcan, Uğur, Yılmaz, Canan Uğur, Orhan, Nurcan, Düzgün, Poyraz, Ceylan, Umut Deniz, Arıcan, Nadir, Karahüseyinoğlu, Serçin, Şahin, Gizem Nur, Ahıshalı, Bülent, Kaya, Mehmet, Aydin, Sidar, Klopstein, Armelle, Engelhardt, Britta, Baumann, Julia, Tsao, Chih-Chieh, Huang, Sheng-Fu, Ogunshola, Omolara, Boytsova, Elizaveta B., Morgun, Andrey V., Khilazheva, Elena D., Pozhilenkova, Elena A., Gorina, Yana V., Martynova, Galina P., Salmina, Alla B., Bueno, David, Garcia-Fernàndez, Jordi, Castro, Victor, Skowronska, Marta, Toborek, Michal, Chupel, Matheus Uba, Minuzzi, Luciele Guerra, Filaire, Edith, Teixeira, Ana Maria, Corsi, Mariangela, Versele, Romain, Fuso, Andrea, Sevin, Emmanuel, Di Lorenzo, Cherubino, Businaro, Rita, Fenart, Laurence, Gosselet, Fabien, Candela, Pietra, Deli, Mária A., Delaney, Conor, O’Keefe, Eoin, Farrell, Michael, Doyle, Sarah, Campbell, Matthew, Drewes, Lester R., Appelt-Menzel, A., Cubukova, A., Metzger, M., Fischer, R., Francisco, David M. F., Bruggmann, Rémy, Fries, Alexa, Blecharz, Kinga G., Wagner, Josephin, Winkler, Lars, Schneider, Ulf, Vajkoczy, Peter, Furuse, Mikio, Gabbert, Lydia, Dilling, Christina, Sisario, Dmitri, Soukhoroukov, Vladimir, Burek, Malgorzata, Guérit, S., Fidan, E., Devraj, K., Czupalla, C. J., Macas, J., Thom, S., Plate, K. H., Gerhardt, H., Liebner, S., Harazin, András, Bocsik, Alexandra, Váradi, Judit, Fenyvesi, Ferenc, Tubak, Vilmos, Vecsernyés, Miklós, Helms, Hans Christian, Waagepetersen, Helle Sønderby, Nielsen, Carsten Uhd, Brodin, Birger, Hoyk, Zsófia, Tóth, Melinda E., Lénárt, Nikolett, Dukay, Brigitta, Kittel, Ágnes, Vígh, Judit, Veszelka, Szilvia, Walter, Fruzsina, Zvara, Ágnes, Puskás, László, Sántha, Miklós, Engelhardt, Sabrina, Ogunshola, Omolara O., Huber, Anna, Reitner, Alexander, Osmen, Samar, Hahn, Kathrin, Bounzina, Neli, Gerhartl, Anna, Schönegger, Anna, Steinkellner, Hannes, Laccone, Franco, Neuhaus, Winfried, Hudson, Natalie, Celkova, Lucia, Iltzsche, Anne, Drndarski, Svetlana, Begley, David J, Janiurek, Mette Mathiesen, Kucharz, Krzysztof, Christoffersen, Christina, Nielsen, Lars Bo, Lauritzen, Martin, Johnson, Rebecca H, Kho, Dan T, O’Carroll, Simon J, Angel, Catherine E, Graham, E. Scott, Pereira, Jennifer, Karali, Christina Simoglou, Cheng, Vinton, Zarghami, Niloufar, Soto, Manuel Sarmiento, Couch, Yvonne, Anthony, Daniel C., Sibson, Nicola R., Kealy, John, Keep, Richard F., Routhe, Lisa J., Xiang, Jianming, Ye, Hong, Hua, Ya, Moos, Torben, Xi, Guohua, Kristensen, M., Bach, A., Strømgaard, K., Kutuzov, Nikolay, Lopes-Pinheiro, Melissa A., Lim, Jamie, Kamermans, Alwin, van Horssen, Jack, Unger, Wendy W.J., Fontijn, Ruud, de Vries, Helga E., Majerova, Petra, Garruto, Ralph M., Marchetti, Luca, Francisco, David, Gruber, Isabelle, Lyck, Ruth, Mészáros, Mária, Porkoláb, Gergő, Kiss, Lóránd, Pilbat, Ana-Maria, Török, Zsolt, Bozsó, Zsolt, Fülöp, Lívia, Michalicova, Alena, Galba, Jaroslav, Mihaljevic, Sandra, Novak, Michal, Kovac, Andrej, Morofuji, Yoichi, Fujimoto, Takashi, Watanabe, Daisuke, Nakagawa, Shinsuke, Ujifuku, Kenta, Horie, Nobutaka, Izumo, Tsuyoshi, Anda, Takeo, Matsuo, Takayuki, Niu, Fang, Buch, Shilpa, Nyúl-Tóth, Ádám, Kozma, Mihály, Nagyőszi, Péter, Nagy, Krisztina, Fazakas, Csilla, Haskó, János, Molnár, Kinga, Farkas, Attila E., Galajda, Péter, Wilhelm, Imola, Krizbai, István A., Kelly, Eoin, Wallace, Eugene, Greene, Chris, Hughes, Stephanie, Kealy, John, Doyle, Niamh, Humphries, Marian M., Grant, Gerald A., Friedman, Alon, Veksler, Ronel, Molloy, Michael G., Meaney, James F., Pender, Niall, Doherty, Colin P., Park, Minseon, Liskiewicz, Arkadiusz, Przybyla, Marta, Kasprowska-Liśkiewicz, Daniela, Nowacka-Chmielewska, Marta, Malecki, Andrzej, Pombero, Ana, Garcia-Lopez, Raquel, Martinez-Morga, Marta, Martinez, Salvador, Prager, Ofer, Solomon-Kamintsky, Lyna, Schoknecht, Karl, Bar-Klein, Guy, Milikovsky, Dan, Vazana, Udi, Rosenbach, Dror, Kovács, Richard, Friedman, Alon, Radak, Zsolt, Rodríguez-Lorenzo, Sabela, Bruggmann, Remy, Kooij, Gijs, de Vries, Helga E, Oxana, Semyachkina-Glushkovskaya, Denis, Bragin, Elena, Vodovozova, Anna, Alekseeva, Alla, Salmina, Vladimir, Salmin, Andrey, Morgun, Nataliya, Malinovskaya, Elena, Khilazheva, Elizaveta, Boytsova, Alexander, Shirokov, Nikita, Navolokin, Alla, Bucharskaya, Yirong, Yang, Arkady, Abdurashitov, Artem, Gekalyuk, Mariya, Ulanova, Anastasia, Shushunova, Madina, Bodrova, Artem, Sagatova, Alexander, Khorovodov, Esmat, Shareef Ali, Valery, Pavlov, Artem, Tuchin, Jürgen, Kurths, de Abreu, Marcelle Silva, Calpena, Ana C., Espina, Marta, García, Maria Luisa, Romero, Ignacio A., Male, David, Storck, Steffen, Hartz, Anika, Pahnke, Jens, Surma, Claus U., Surma, M., Giżejewski, Z., Zieliński, H., Szczepkowska, Aleksandra, Kowalewska, Marta, Krawczynska, Agata, Herman, Andrzej P., Skipor, Janina, Kachappilly, Nicole, Veenstra, Mike, Rivera, Rosiris Leon, Williams, Dionna W., Morgello, Susan, Berman, Joan W., Wyneken, Ursula, Batiz, Luis Federico, Temizyürek, Arzu, Khodadust, Rouhollah, Küçük, Mutlu, Gürses, Candan, Emik, Serkan, Zielińska, Magdalena, Obara-Michlewska, Marta, Milewski, Krzysztof, Skonieczna, Edyta, Fręśko, Inez, Neuwelt, Edward A., Maria, Ana Raquel Santa, Bras, Ana Rita, Lipka, Dóra, Valkai, Sándor, Kincses, András, Dér, András, Deli, Maria A.
Publicado 2017