PIK3CA mutation and colorectal cancer precision medicine

por Hamada, Tsuyoshi, Nowak, Jonathan A., Ogino, Shuji
Publicado 2017

Immortalization of mouse myogenic cells can occur without loss of p16(INK4a), p19(ARF), or p53 and is accelerated by inactivation of Bax

por Nowak, Jonathan A, Malowitz, Jonathan, Girgenrath, Mahasweta, Kostek, Christine A, Kravetz, Amanda J, Dominov, Janice A, Miller, Jeffrey Boone
Publicado 2004

Integration of pharmacology, molecular pathology, and population data science to support precision gastrointestinal oncology

por Ogino, Shuji, Jhun, Iny, Mata, Douglas A., Soong, Thing Rinda, Hamada, Tsuyoshi, Liu, Li, Nishihara, Reiko, Giannakis, Marios, Cao, Yin, Manson, JoAnn E., Nowak, Jonathan A., Chan, Andrew T.
Publicado 2017

Biomarker correlation network in colorectal carcinoma by tumor anatomic location

por Nishihara, Reiko, Glass, Kimberly, Mima, Kosuke, Hamada, Tsuyoshi, Nowak, Jonathan A., Qian, Zhi Rong, Kraft, Peter, Giovannucci, Edward L., Fuchs, Charles S., Chan, Andrew T., Quackenbush, John, Ogino, Shuji, Onnela, Jukka-Pekka
Publicado 2017

Spatially resolved multimarker evaluation of CD274 (PD-L1)/PDCD1 (PD-1) immune checkpoint expression and macrophage polarisation in colorectal cancer

por Elomaa, Hanna, Ahtiainen, Maarit, Väyrynen, Sara A., Ogino, Shuji, Nowak, Jonathan A., Lau, Mai Chan, Helminen, Olli, Wirta, Erkki-Ville, Seppälä, Toni T., Böhm, Jan, Mecklin, Jukka-Pekka, Kuopio, Teijo, Väyrynen, Juha P.
Publicado 2023

Prognostic significance of spatial and density analysis of T lymphocytes in colorectal cancer

por Elomaa, Hanna, Ahtiainen, Maarit, Väyrynen, Sara A., Ogino, Shuji, Nowak, Jonathan A., Friman, Marjukka, Helminen, Olli, Wirta, Erkki-Ville, Seppälä, Toni T., Böhm, Jan, Mäkinen, Markus J., Mecklin, Jukka-Pekka, Kuopio, Teijo, Väyrynen, Juha P.
Publicado 2022

Machine learning links T cell function and spatial localization to neoadjuvant immunotherapy and clinical outcome in pancreatic cancer

por Blise, Katie E., Sivagnanam, Shamilene, Betts, Courtney B., Betre, Konjit, Kirchberger, Nell, Tate, Benjamin, Furth, Emma E., Dias Costa, Andressa, Nowak, Jonathan A., Wolpin, Brian M., Vonderheide, Robert H., Goecks, Jeremy, Coussens, Lisa M., Byrne, Katelyn T.
Publicado 2023

Pancreatic cancer is associated with medication changes prior to clinical diagnosis

por Zhang, Yin, Wang, Qiao-Li, Yuan, Chen, Lee, Alice A., Babic, Ana, Ng, Kimmie, Perez, Kimberly, Nowak, Jonathan A., Lagergren, Jesper, Stampfer, Meir J., Giovannucci, Edward L., Sander, Chris, Rosenthal, Michael H., Kraft, Peter, Wolpin, Brian M.
Publicado 2023

Dairy intake during adolescence and risk of colorectal adenoma later in life

por Nimptsch, Katharina, Lee, Dong Hoon, Zhang, Xuehong, Song, Mingyang, Farvid, Maryam S., Rezende, Leandro F. M., Cao, Yin, Chan, Andrew T., Fuchs, Charles, Meyerhardt, Jeffrey, Nowak, Jonathan A., Willett, Walter C., Ogino, Shuji, Giovannucci, Edward, Pischon, Tobias, Wu, Kana
Publicado 2021

Continuity of transcriptomes among colorectal cancer subtypes based on meta-analysis

por Ma, Siyuan, Ogino, Shuji, Parsana, Princy, Nishihara, Reiko, Qian, Zhirong, Shen, Jeanne, Mima, Kosuke, Masugi, Yohei, Cao, Yin, Nowak, Jonathan A., Shima, Kaori, Hoshida, Yujin, Giovannucci, Edward L., Gala, Manish K., Chan, Andrew T., Fuchs, Charles S., Parmigiani, Giovanni, Huttenhower, Curtis, Waldron, Levi
Publicado 2018

Family history of cancer, Ashkenazi Jewish ancestry, and pancreatic cancer risk

por Hamada, Tsuyoshi, Yuan, Chen, Yurgelun, Matthew B., Perez, Kimberly, Khalaf, Natalia, Morales-Oyarvide, Vicente, Babic, Ana, Nowak, Jonathan A., Rubinson, Douglas A., Giannakis, Marios, Ng, Kimmie, Kraft, Peter, Stampfer, Meir J., Giovannucci, Edward L., Fuchs, Charles S., Ogino, Shuji, Wolpin, Brian M.
Publicado 2019

Clinical Pan-Cancer Assessment of Mismatch Repair Deficiency Using Tumor-Only, Targeted Next-Generation Sequencing

por Albayrak, Adem, Garrido-Castro, Ana C., Giannakis, Marios, Umeton, Renato, Manam, Monica Devi, Stover, Elizabeth H., Porter, Rebecca L., Johnson, Bruce E., Liaw, Kai-Li, Amonkar, Mayur, Church, Alanna J., Janeway, Katherine A., Nowak, Jonathan A., Sholl, Lynette, Lin, Nancy U., Johnson, Jason M.
Publicado 2020

Tumor LINE-1 methylation level and colorectal cancer location in relation to patient survival

por Mima, Kosuke, Nowak, Jonathan A., Qian, Zhi Rong, Cao, Yin, Song, Mingyang, Masugi, Yohei, Shi, Yan, da Silva, Annacarolina, Gu, Mancang, Li, Wanwan, Hamada, Tsuyoshi, Zhang, Xuehong, Wu, Kana, Meyerhardt, Jeffrey A., Baba, Hideo, Giovannucci, Edward L., Chan, Andrew T., Fuchs, Charles S., Ogino, Shuji, Nishihara, Reiko
Publicado 2016

Discovery and Features of an Alkylating Signature in Colorectal Cancer

por Gurjao, Carino, Zhong, Rong, Haruki, Koichiro, Li, Yvonne Y., Spurr, Liam F., Lee-Six, Henry, Reardon, Brendan, Ugai, Tomotaka, Zhang, Xuehong, Cherniack, Andrew D., Song, Mingyang, Van Allen, Eliezer M., Meyerhardt, Jeffrey A., Nowak, Jonathan A., Giovannucci, Edward L., Fuchs, Charles S., Wu, Kana, Ogino, Shuji, Giannakis, Marios
Publicado 2021

Desmoplastic Reaction, Immune Cell Response, and Prognosis in Colorectal Cancer

por Akimoto, Naohiko, Väyrynen, Juha P., Zhao, Melissa, Ugai, Tomotaka, Fujiyoshi, Kenji, Borowsky, Jennifer, Zhong, Rong, Haruki, Koichiro, Arima, Kota, Lau, Mai Chan, Kishikawa, Junko, Twombly, Tyler S., Takashima, Yasutoshi, Song, Mingyang, Zhang, Xuehong, Wu, Kana, Chan, Andrew T., Meyerhardt, Jeffrey A., Giannakis, Marios, Nowak, Jonathan A., Ogino, Shuji
Publicado 2022

Tumor Long Interspersed Nucleotide Element-1 (LINE-1) Hypomethylation in Relation to Age of Colorectal Cancer Diagnosis and Prognosis

por Akimoto, Naohiko, Zhao, Melissa, Ugai, Tomotaka, Zhong, Rong, Lau, Mai Chan, Fujiyoshi, Kenji, Kishikawa, Junko, Haruki, Koichiro, Arima, Kota, Twombly, Tyler S., Zhang, Xuehong, Giovannucci, Edward L., Wu, Kana, Song, Mingyang, Chan, Andrew T., Cao, Yin, Meyerhardt, Jeffrey A., Ng, Kimmie, Giannakis, Marios, Väyrynen, Juha P., Nowak, Jonathan A., Ogino, Shuji
Publicado 2021

Healthy and unhealthy plant‐based diets in relation to the incidence of colorectal cancer overall and by molecular subtypes

por Wang, Fenglei, Ugai, Tomotaka, Haruki, Koichiro, Wan, Yi, Akimoto, Naohiko, Arima, Kota, Zhong, Rong, Twombly, Tyler S., Wu, Kana, Yin, Kanhua, Chan, Andrew T., Giannakis, Marios, Nowak, Jonathan A., Meyerhardt, Jeffrey A., Liang, Liming, Song, Mingyang, Smith‐Warner, Stephanie A., Zhang, Xuehong, Giovannucci, Edward L., Willett, Walter C., Ogino, Shuji
Publicado 2022

Inverse relationship between Fusobacterium nucleatum amount and tumor CD274 (PD‐L1) expression in colorectal carcinoma

por Ugai, Tomotaka, Shimizu, Takashi, Kawamura, Hidetaka, Ugai, Satoko, Takashima, Yasutoshi, Usui, Genki, Väyrynen, Juha P, Okadome, Kazuo, Haruki, Koichiro, Akimoto, Naohiko, Masugi, Yohei, da Silva, Annacarolina, Mima, Kosuke, Zhang, Xuehong, Chan, Andrew T, Wang, Molin, Garrett, Wendy S, Freeman, Gordon J, Meyerhardt, Jeffrey A, Nowak, Jonathan A, Song, Mingyang, Giannakis, Marios, Ogino, Shuji
Publicado 2023

Coffee Intake and Colorectal Cancer Incidence According to T-Cell Response

por Ugai, Tomotaka, Haruki, Koichiro, Väyrynen, Juha P, Zhong, Rong, Borowsky, Jennifer, Fujiyoshi, Kenji, Lau, Mai Chan, Zhao, Melissa, Akimoto, Naohiko, Chang, Tzuu-Wang, Kishikawa, Junko, Arima, Kota, Shi, Shan-Shan, Gu, Simeng, Fuchs, Charles S, Giovannucci, Edward L, Giannakis, Marios, Zhang, Xuehong, Song, Mingyang, Meyerhardt, Jeffrey A, Wang, Molin, Nowak, Jonathan A, Ogino, Shuji
Publicado 2020

Association of PIK3CA mutation and PTEN loss with expression of CD274 (PD-L1) in colorectal carcinoma

por Ugai, Tomotaka, Zhao, Melissa, Shimizu, Takashi, Akimoto, Naohiko, Shi, Shanshan, Takashima, Yasutoshi, Zhong, Rong, Lau, Mai Chan, Haruki, Koichiro, Arima, Kota, Fujiyoshi, Kenji, Langworthy, Benjamin, Masugi, Yohei, da Silva, Annacarolina, Nosho, Katsuhiko, Baba, Yoshifumi, Song, Mingyang, Chan, Andrew T., Wang, Molin, Meyerhardt, Jeffrey A., Giannakis, Marios, Väyrynen, Juha P., Nowak, Jonathan A., Ogino, Shuji
Publicado 2021