Rapid Synthesis and Screening of Chemically Activated Transcription Factors with GFP-based Reporters

por McIsaac, R. Scott, Oakes, Benjamin L., Botstein, David, Noyes, Marcus B.
Publicado 2013

Deep sequencing of large library selections allows computational discovery of diverse sets of zinc fingers that bind common targets

por Persikov, Anton V., Rowland, Elizabeth F., Oakes, Benjamin L., Singh, Mona, Noyes, Marcus B.
Publicado 2014

A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system

por Noyes, Marcus B., Meng, Xiangdong, Wakabayashi, Atsuya, Sinha, Saurabh, Brodsky, Michael H., Wolfe, Scot A.
Publicado 2008

Synthetic gene expression perturbation systems with rapid, tunable, single-gene specificity in yeast

por McIsaac, R. Scott, Oakes, Benjamin L., Wang, Xin, Dummit, Krysta A., Botstein, David, Noyes, Marcus B.
Publicado 2013

Recognition models to predict DNA-binding specificities of homeodomain proteins

por Christensen, Ryan G., Enuameh, Metewo Selase, Noyes, Marcus B., Brodsky, Michael H., Wolfe, Scot A., Stormo, Gary D.
Publicado 2012

A systematic survey of the Cys(2)His(2) zinc finger DNA-binding landscape

por Persikov, Anton V., Wetzel, Joshua L., Rowland, Elizabeth F., Oakes, Benjamin L., Xu, Denise J., Singh, Mona, Noyes, Marcus B.
Publicado 2015

Exploring the DNA-recognition potential of homeodomains

por Chu, Stephanie W., Noyes, Marcus B., Christensen, Ryan G., Pierce, Brian G., Zhu, Lihua J., Weng, Zhiping, Stormo, Gary D., Wolfe, Scot A.
Publicado 2012

Engineered dual selection for directed evolution of SpCas9 PAM specificity

por Goldberg, Gregory W., Spencer, Jeffrey M., Giganti, David O., Camellato, Brendan R., Agmon, Neta, Ichikawa, David M., Boeke, Jef D., Noyes, Marcus B.
Publicado 2021

The geometric influence on the Cys(2)His(2) zinc finger domain and functional plasticity

por Mueller, April L, Corbi-Verge, Carles, Giganti, David O, Ichikawa, David M, Spencer, Jeffrey M, MacRae, Mark, Garton, Michael, Kim, Philip M, Noyes, Marcus B
Publicado 2020

Engineered transcription-associated Cas9 targeting in eukaryotic cells

por Goldberg, Gregory W., Kogenaru, Manjunatha, Keegan, Sarah, Haase, Max A. B., Kagermazova, Larisa, Arias, Mauricio A., Onyebeke, Kenenna, Adams, Samantha, Fenyö, David, Noyes, Marcus B., Boeke, Jef D.
Publicado 2023

Multi-reporter selection for the design of active and more specific zinc-finger nucleases for genome editing

por Oakes, Benjamin L., Xia, Danny F., Rowland, Elizabeth F., Xu, Denise J., Ankoudinova, Irina, Borchardt, Jennifer S., Zhang, Lei, Li, Patrick, Miller, Jeffrey C., Rebar, Edward J., Noyes, Marcus B.
Publicado 2016

A universal deep-learning model for zinc finger design enables transcription factor reprogramming

por Ichikawa, David M., Abdin, Osama, Alerasool, Nader, Kogenaru, Manjunatha, Mueller, April L., Wen, Han, Giganti, David O., Goldberg, Gregory W., Adams, Samantha, Spencer, Jeffrey M., Razavi, Rozita, Nim, Satra, Zheng, Hong, Gionco, Courtney, Clark, Finnegan T., Strokach, Alexey, Hughes, Timothy R., Lionnet, Timothee, Taipale, Mikko, Kim, Philip M., Noyes, Marcus B.
Publicado 2023