Pharmacokinetics and Pharmacodynamics of Ertugliflozin in Healthy Japanese and Western Subjects

por Li, Yinhua, Nucci, Gianluca, Yamamoto, Yuichi, Fediuk, Daryl J., Sahasrabudhe, Vaishali
Publicado 2021

Achieving end-to-end success in the clinic: Pfizer’s learnings on R&D productivity

por Fernando, Kathy, Menon, Sandeep, Jansen, Kathrin, Naik, Prakash, Nucci, Gianluca, Roberts, John, Wu, Shuang Sarah, Dolsten, Mikael
Publicado 2022

End‐to‐end application of model‐informed drug development for ertugliflozin, a novel sodium‐glucose cotransporter 2 inhibitor

por Fediuk, Daryl J., Nucci, Gianluca, Dawra, Vikas K., Callegari, Ernesto, Zhou, Susan, Musante, Cynthia J., Liang, Yali, Sweeney, Kevin, Sahasrabudhe, Vaishali
Publicado 2021

Overview of the Clinical Pharmacology of Ertugliflozin, a Novel Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor

por Fediuk, Daryl J., Nucci, Gianluca, Dawra, Vikas Kumar, Cutler, David L., Amin, Neeta B., Terra, Steven G., Boyd, Rebecca A., Krishna, Rajesh, Sahasrabudhe, Vaishali
Publicado 2020

Innovative Randomized Phase I Study and Dosing Regimen Selection to Accelerate and Inform Pivotal COVID‐19 Trial of Nirmatrelvir

por Singh, Ravi Shankar P., Toussi, Sima S., Hackman, Frances, Chan, Phylinda L., Rao, Rohit, Allen, Richard, Van Eyck, Lien, Pawlak, Sylvester, Kadar, Eugene P., Clark, Frances, Shi, Haihong, Anderson, Annaliesa S., Binks, Michael, Menon, Sandeep, Nucci, Gianluca, Bergman, Arthur
Publicado 2022

Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Intravenous Infusions of PF-07304814 (Lufotrelvir) in Participants Hospitalized With COVID-19

por Robinson, Philip, Toussi, Sima S, Aggarwal, Sudeepta, Bergman, Arthur, Zhu, Tong, Hackman, Frances, Sathish, Jean G, Updyke, Lawrence, Loudon, Peter, Krishna, Ganesh, Clevenbergh, Philippe, Hernandez-Mora, Miguel Gorgolas, Cisneros Herreros, Jose Miguel, Albertson, Timothy E, Dougan, Michael, Thacker, Amber, Baniecki, Mary Lynn, Soares, Holly, Whitlock, Mark, Nucci, Gianluca, Menon, Sandeep, Anderson, Annaliesa S, Binks, Michael
Publicado 2023