Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity

por Nuñez, James K., Lee, Amy S.Y., Engelman, Alan, Doudna, Jennifer A.
Publicado 2015

Foreign DNA capture during CRISPR–Cas adaptive immunity

por Nuñez, James K., Harrington, Lucas B., Kranzusch, Philip J., Engelman, Alan N., Doudna, Jennifer A.
Publicado 2015

Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity

por Nuñez, James K., Kranzusch, Philip J., Noeske, Jonas, Wright, Addison V., Davies, Christopher W., Doudna, Jennifer A.
Publicado 2014

Inducible and multiplex gene regulation using CRISPR-Cpf1-based transcription factors

por Tak, Y. Esther, Kleinstiver, Benjamin P., Nuñez, James K., Hsu, Jonathan Y., Horng, Joy E., Gong, Jingyi, Weissman, Jonathan S., Joung, J. Keith
Publicado 2017

Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1

por Musselman, Catherine A., Avvakumov, Nikita, Watanabe, Reiko, Abraham, Christopher G., Lalonde, Marie-Eve, Hong, Zehui, Allen, Christopher, Roy, Siddhartha, Nuñez, James K., Nickoloff, Jac, Kulesza, Caroline A., Yasui, Akira, Côté, Jacques, Kutateladze, Tatiana G.
Publicado 2012

Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq

por Sunshine, Sara, Puschnik, Andreas S., Replogle, Joseph M., Laurie, Matthew T., Liu, Jamin, Zha, Beth Shoshana, Nuñez, James K., Byrum, Janie R., McMorrow, Aidan H., Frieman, Matthew B., Winkler, Juliane, Qiu, Xiaojie, Rosenberg, Oren S., Leonetti, Manuel D., Ye, Chun Jimmie, Weissman, Jonathan S., DeRisi, Joseph L., Hein, Marco Y.
Publicado 2023

BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2

por Samelson, Avi J., Tran, Quang Dinh, Robinot, Rémy, Carrau, Lucia, Rezelj, Veronica V., Mac Kain, Alice, Chen, Merissa, Ramadoss, Gokul N., Guo, Xiaoyan, Lim, Shion A., Lui, Irene, Nunez, James, Rockwood, Sarah J., Wang, Jianhui, Liu, Na, Carlson-Stevermer, Jared, Oki, Jennifer, Maures, Travis, Holden, Kevin, Weissman, Jonathan S., Wells, James A., Conklin, Bruce R., TenOever, Benjamin R., Chakrabarti, Lisa A., Vignuzzi, Marco, Tian, Ruilin, Kampmann, Martin
Publicado 2021

BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2

por Samelson, Avi J., Tran, Quang Dinh, Robinot, Rémy, Carrau, Lucia, Rezelj, Veronica V., Kain, Alice Mac, Chen, Merissa, Ramadoss, Gokul N., Guo, Xiaoyan, Lim, Shion A., Lui, Irene, Nuñez, James K., Rockwood, Sarah J., Wang, Jianhui, Liu, Na, Carlson-Stevermer, Jared, Oki, Jennifer, Maures, Travis, Holden, Kevin, Weissman, Jonathan S., Wells, James A., Conklin, Bruce R., TenOever, Benjamin R., Chakrabarti, Lisa A., Vignuzzi, Marco, Tian, Ruilin, Kampmann, Martin
Publicado 2022