Caenorhabditis elegans as a model system for studying non-cell-autonomous mechanisms in protein-misfolding diseases

por Nussbaum-Krammer, Carmen I., Morimoto, Richard I.
Publicado 2014

Molecular Chaperones: A Double-Edged Sword in Neurodegenerative Diseases

por Tittelmeier, Jessica, Nachman, Eliana, Nussbaum-Krammer, Carmen
Publicado 2020

α-Synuclein Strains: Does Amyloid Conformation Explain the Heterogeneity of Synucleinopathies?

por Hoppe, Simon Oliver, Uzunoğlu, Gamze, Nussbaum-Krammer, Carmen
Publicado 2021

C. elegans Models to Study the Propagation of Prions and Prion-Like Proteins

por Sandhof, Carl Alexander, Hoppe, Simon Oliver, Tittelmeier, Jessica, Nussbaum-Krammer, Carmen
Publicado 2020

Dissecting aggregation and seeding dynamics of α-Syn polymorphs using the phasor approach to FLIM

por Tittelmeier, Jessica, Druffel-Augustin, Silke, Alik, Ania, Melki, Ronald, Nussbaum-Krammer, Carmen
Publicado 2022

Spreading of a Prion Domain from Cell-to-Cell by Vesicular Transport in Caenorhabditis elegans

por Nussbaum-Krammer, Carmen I., Park, Kyung-Won, Li, Liming, Melki, Ronald, Morimoto, Richard I.
Publicado 2013

Reducing INS-IGF1 signaling protects against non-cell autonomous vesicle rupture caused by SNCA spreading

por Sandhof, Carl Alexander, Hoppe, Simon Oliver, Druffel-Augustin, Silke, Gallrein, Christian, Kirstein, Janine, Voisine, Cindy, Nussbaum-Krammer, Carmen
Publicado 2019

Protein Quality Control Pathways at the Crossroad of Synucleinopathies

por De Mattos, Eduardo P., Wentink, Anne, Nussbaum-Krammer, Carmen, Hansen, Christian, Bergink, Steven, Melki, Ronald, Kampinga, Harm H.
Publicado 2020

The HSP110/HSP70 disaggregation system generates spreading‐competent toxic α‐synuclein species

por Tittelmeier, Jessica, Sandhof, Carl Alexander, Ries, Heidrun Maja, Druffel‐Augustin, Silke, Mogk, Axel, Bukau, Bernd, Nussbaum‐Krammer, Carmen
Publicado 2020

The cytoprotective sequestration activity of small heat shock proteins is evolutionarily conserved

por Shrivastava, Aseem, Sandhof, Carl Alexander, Reinle, Kevin, Jawed, Areeb, Ruger-Herreros, Carmen, Schwarz, Dominic, Creamer, Declan, Nussbaum-Krammer, Carmen, Mogk, Axel, Bukau, Bernd
Publicado 2022

Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species

por Nachman, Eliana, Wentink, Anne S., Madiona, Karine, Bousset, Luc, Katsinelos, Taxiarchis, Allinson, Kieren, Kampinga, Harm, McEwan, William A., Jahn, Thomas R., Melki, Ronald, Mogk, Axel, Bukau, Bernd, Nussbaum-Krammer, Carmen
Publicado 2020

NSs amyloid formation is associated with the virulence of Rift Valley fever virus in mice

por Léger, Psylvia, Nachman, Eliana, Richter, Karsten, Tamietti, Carole, Koch, Jana, Burk, Robin, Kummer, Susann, Xin, Qilin, Stanifer, Megan, Bouloy, Michèle, Boulant, Steeve, Kräusslich, Hans-Georg, Montagutelli, Xavier, Flamand, Marie, Nussbaum-Krammer, Carmen, Lozach, Pierre-Yves
Publicado 2020