The remote allosteric control of Orai channel gating

por Zhou, Yandong, Nwokonko, Robert M., Baraniak, James H., Trebak, Mohamed, Lee, Kenneth P. K., Gill, Donald L.
Publicado 2019

STIM1 dimers undergo unimolecular coupling to activate Orai1 channels

por Zhou, Yandong, Wang, Xizhuo, Wang, Xianming, Loktionova, Natalia A., Cai, Xiangyu, Nwokonko, Robert M., Vrana, Erin, Wang, Youjun, Rothberg, Brad S., Gill, Donald L.
Publicado 2015

The STIM1-binding site nexus remotely controls Orai1 channel gating

por Zhou, Yandong, Cai, Xiangyu, Loktionova, Natalia A., Wang, Xianming, Nwokonko, Robert M., Wang, Xizhuo, Wang, Youjun, Rothberg, Brad S., Trebak, Mohamed, Gill, Donald L.
Publicado 2016

Orai channel C-terminal peptides are key modulators of STlM-Orai coupling and calcium signal generation

por Baraniak, James H., Zhou, Yandong, Nwokonko, Robert M., Jennette, Michelle R., Kazzaz, Sarah A., Stenson, Jazmin M., Whitsell, Abigale L., Wang, Youjun, Trebak, Mohamed, Gill, Donald L.
Publicado 2021

An apical Phe-His pair defines the Orai1-coupling site and its occlusion within STIM1

por Zhou, Yandong, Jennette, Michelle R., Ma, Guolin, Kazzaz, Sarah A., Baraniak, James H., Nwokonko, Robert M., Groff, Mallary L., Velasquez-Reynel, Marcela, Huang, Yun, Wang, Youjun, Gill, Donald L.
Publicado 2023

Identification of molecular determinants that govern distinct STIM2 activation dynamics

por Zheng, Sisi, Ma, Guolin, He, Lian, Zhang, Tian, Li, Jia, Yuan, Xiaoman, Nguyen, Nhung T., Huang, Yun, Zhang, Xiaoyan, Gao, Ping, Nwokonko, Robert, Gill, Donald L., Dong, Hao, Zhou, Yubin, Wang, Youjun
Publicado 2018

A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction

por Zhang, Xuexin, Pathak, Trayambak, Yoast, Ryan, Emrich, Scott, Xin, Ping, Nwokonko, Robert M., Johnson, Martin, Wu, Shilan, Delierneux, Céline, Gueguinou, Maxime, Hempel, Nadine, Putney, James W., Gill, Donald L., Trebak, Mohamed
Publicado 2019

Calcium store refilling and STIM activation in STIM- and Orai-deficient cell lines

por Zheng, Sisi, Zhou, Lijuan, Ma, Guolin, Zhang, Tian, Liu, Jindou, Li, Jia, Nguyen, Nhung T., Zhang, Xiaoyan, Li, Wanjie, Nwokonko, Robert, Zhou, Yandong, Zhao, Fukuan, Liu, Jingguo, Huang, Yun, Gill, Donald L., Wang, Youjun
Publicado 2018