Major antigenic site B of human influenza H3N2 viruses has an evolving local fitness landscape

por Wu, Nicholas C., Otwinowski, Jakub, Thompson, Andrew J., Nycholat, Corwin M., Nourmohammad, Armita, Wilson, Ian A.
Publicado 2020

Antigen Delivery to Macrophages Using Liposomal Nanoparticles Targeting Sialoadhesin/CD169

por Chen, Weihsu C., Kawasaki, Norihito, Nycholat, Corwin M., Han, Shoufa, Pilotte, Julie, Crocker, Paul R., Paulson, James C.
Publicado 2012

The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery

por Sommer, Roman, Wagner, Stefanie, Varrot, Annabelle, Nycholat, Corwin M., Khaledi, Ariane, Häussler, Susanne, Paulson, James C., Imberty, Anne, Titz, Alexander
Publicado 2016

A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site

por Wu, Nicholas C., Thompson, Andrew J., Xie, Jia, Lin, Chih-Wei, Nycholat, Corwin M., Zhu, Xueyong, Lerner, Richard A., Paulson, James C., Wilson, Ian A.
Publicado 2018

A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine

por Wu, Nicholas C., Zost, Seth J., Thompson, Andrew J., Oyen, David, Nycholat, Corwin M., McBride, Ryan, Paulson, James C., Hensley, Scott E., Wilson, Ian A.
Publicado 2017

Highly Pathogenic Influenza A(H5Nx) Viruses with Altered H5 Receptor-Binding Specificity

por Guo, Hongbo, de Vries, Erik, McBride, Ryan, Dekkers, Jojanneke, Peng, Wenjie, Bouwman, Kim M., Nycholat, Corwin, Verheije, M. Helene, Paulson, James C., van Kuppeveld, Frank J.M., de Haan, Cornelis A.M.
Publicado 2017

Preventing an Antigenically Disruptive Mutation in Egg-Based H3N2 Seasonal Influenza Vaccines by Mutational Incompatibility

por Wu, Nicholas C., Lv, Huibin, Thompson, Andrew J., Wu, Douglas C., Ng, Wilson W.S., Kadam, Rameshwar U., Lin, Chih-Wei, Nycholat, Corwin M., McBride, Ryan, Liang, Weiwen, Paulson, James C., Mok, Chris K.P., Wilson, Ian A.
Publicado 2019

Revealing the Specificity of Human H1 Influenza A Viruses to Complex N-Glycans

por Canales, Angeles, Sastre, Javier, Orduña, Jose M., Spruit, Cindy M., Pérez-Castells, Javier, Domínguez, Gema, Bouwman, Kim M., van der Woude, Roosmarijn, Cañada, Francisco Javier, Nycholat, Corwin M., Paulson, James C., Boons, Geert-Jan, Jiménez-Barbero, Jesús, de Vries, Robert P.
Publicado 2023

Structures of the Inhibitory Receptor Siglec-8 in Complex with a High-Affinity Sialoside Analogue and a Therapeutic Antibody

por Lenza, Maria Pia, Atxabal, Unai, Nycholat, Corwin, Oyenarte, Iker, Franconetti, Antonio, Quintana, Jon Imanol, Delgado, Sandra, Núñez-Franco, Reyes, Garnica Marroquín, Carmen Teresa, Coelho, Helena, Unione, Luca, Jiménez-Oses, Gonzalo, Marcelo, Filipa, Schubert, Mario, Paulson, James C., Jiménez-Barbero, Jesús, Ereño-Orbea, June
Publicado 2022