Investigating discovery strategies and pharmacological properties of stereodefined phosphorodithioate LNA gapmers

por Duschmalé, Jörg, Schäublin, Adrian, Funder, Erik, Schmidt, Steffen, Kiełpiński, Łukasz J., Nymark, Helle, Jensen, Klaus, Koch, Troels, Duschmalé, Martina, Koller, Erich, Møller, Marianne Ravn, Schadt, Simone, Husser, Christophe, Brink, Andreas, Sewing, Sabine, Minz, Tanja, Wengel, Jesper, Bleicher, Konrad, Li, Meiling
Publicado 2022

TMEM106B reduction does not rescue GRN deficiency in iPSC-derived human microglia and mouse models

por Dominguez, Sara L., Laufer, Benjamin I., Ghosh, Arundhati Sengupta, Li, Qingling, Ruggeri, Gaia, Emani, Maheswara Reddy, Phu, Lilian, Friedman, Brad A., Sandoval, Wendy, Rose, Christopher M., Ngu, Hai, Foreman, Oded, Reichelt, Mike, Juste, Yves, Lalehzadeh, Guita, Hansen, Dennis, Nymark, Helle, Mellal, Denia, Gylling, Helene, Kiełpiński, Łukasz J., Chih, Ben, Bingol, Baris, Hoogenraad, Casper C., Meilandt, William J., Easton, Amy
Publicado 2023